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• W2810604384 abstract "<b><i>Objective:</i></b> Caffeine has been considered a trigger for atrial fibrillation (AF). We conducted a meta-analysis including a dose-response analysis to assess the relationship between caffeine consumed and incidence of AF. <b><i>Methods:</i></b> Data from selected studies represented 176,675 subjects (AF in 9,987 [5.7%]). Caffeine content varied widely, ranging from 40 to 180 mg per cup of coffee. For purposes of the calculations in this study, we assumed 140 mg of caffeine in a standard 12-oz cup of coffee. <b><i>Results:</i></b> No significant difference was found in AF incidence when the subjects consuming less than 2 cups of coffee per day were compared to subjects with higher consumption, 1.068 (0.937–1.216). The risk of AF was higher among subjects consuming less than 2 cups of coffee daily when compared to higher daily consumption subjects. A lower incidence of AF was found among people consuming more than 436 mg daily. <b><i>Conclusion:</i></b> The incidence of AF is not increased by coffee consumption. In fact, we found a lower incidence of AF when caffeine consumption exceeded 436 mg/day. Therefore, based on available evidence there is no association between caffeine intake and AF risk." @default.
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• W2810604384 date "2018-01-01" @default.
• W2810604384 modified "2023-10-02" @default.
• W2810604384 title "Does Caffeine Consumption Increase the Risk of New-Onset Atrial Fibrillation?" @default.
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• W2810604384 doi "https://doi.org/10.1159/000489843" @default.
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