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- W2810797005 abstract "Micronesians are a rapidly growing population in Hawaii and the continental U.S. Hepatitis B is prevalent in Micronesia, but the consequences in those migrating to the U.S. are unclear. This study characterizes hepatocellular carcinoma in Micronesians with comparisons to other Pacific Islanders.A retrospective evaluation was undertaken of 40 Micronesian and 142 Non-Micronesian Pacific hepatocellular carcinoma patients diagnosed in a large clinical practice in Hawaii from 1993-2017.All Micronesians were born outside of the U.S. Micronesians were younger at diagnosis (52.0 vs 60.2 years, had higher rates of hepatitis B (80% vs 31.2%), a family history of hepatocellular carcinoma (17.5% vs 4.4%) and more tumors <5 cm (64.1% vs 45.2%). Non Micronesian Pacific Islanders had higher rates of Hepatitis C (48.6% vs 22.5%) and hypertension (61.7% vs 32.4%). There was no difference in the proportions of screen-detected tumors, those meeting Milan criteria, tumor stage, or liver function. Micronesians had better 5-year survival rates (48% vs 16.7%).Hepatocellular carcinoma in Micronesians is primarily Hepatitis B-related. Micronesians were equally likely to have hepatocellular carcinoma found with screening, undergo transplant and had better survival. Our study emphasizes the need for hepatitis B screening and hepatocellular carcinoma surveillance in Micronesians." @default.
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- W2810797005 date "2018-01-01" @default.
- W2810797005 modified "2023-10-03" @default.
- W2810797005 title "Hepatocellular Carcinoma in Micronesians, a Growing Pacific Islander Population in the U.S." @default.
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- W2810797005 doi "https://doi.org/10.4236/ojgas.2018.86025" @default.
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