FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2810890325> ?p ?o ?g. }

• W2810890325 endingPage "149" @default.
• W2810890325 startingPage "143" @default.
• W2810890325 abstract "To quantify reports made to the Food and Drug Administration Adverse Event Reporting System (FAERS), create a demographic of patient reports, and examine the cluster of symptoms to correlate consistency of postfinasteride syndrome (PFS) complaints. PFS is a provisional diagnosis encompassing a cluster of sexual, physical, and psychological and/or neurologic symptoms associated with 5-alpha reductase inhibitor use that emerge or continue after discontinuation of medication.FAERS dataset of 5-alpha reductase inhibitors from April 2011 to October 2014 was obtained. Each FAERS report had 16 categories for completion, but not every report was fully completed. Statistical analysis compared variables of interest between the 2 doses of finasteride (1 mg vs 5 mg).From FAERS, 2048 monotherapy cases were identified: 1581 of finasteride 1 mg, 240 of finasteride 5 mg, and 226 of unreported doses. Possibly related to labeling changes, from 2011 to 2014, there was a significant increase in adverse events (AEs) reported involving 1 mg dosing. Finasteride use was reported with many sexual AEs including diminished libido, erectile dysfunction, and ejaculatory complaints. Other common AEs included dermatologic, metabolic, and psychological and/or neurologic complaints. There were more AE reports with the 1 mg dose than the 5 mg dose. One case of dutasteride reported back pain, not generally attributed to PFS.FAERS data suggests that finasteride exposure is reported with a diverse collection of symptoms, particularly in younger men on 1 mg dosage compared to older men on 5 mg. Many of these complaints fall well out of the realm of previously established AEs from long-term controlled studies." @default.
• W2810890325 created "2018-07-10" @default.
• W2810890325 creator A5011893909 @default.
• W2810890325 creator A5013809279 @default.
• W2810890325 creator A5047934585 @default.
• W2810890325 creator A5054919199 @default.
• W2810890325 creator A5064680914 @default.
• W2810890325 creator A5067886311 @default.
• W2810890325 creator A5070841583 @default.
• W2810890325 creator A5079539755 @default.
• W2810890325 creator A5081006357 @default.
• W2810890325 creator A5082716887 @default.
• W2810890325 date "2018-10-01" @default.
• W2810890325 modified "2023-10-03" @default.
• W2810890325 title "A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome" @default.
• W2810890325 cites W1892757024 @default.
• W2810890325 cites W1954064623 @default.
• W2810890325 cites W1970493289 @default.
• W2810890325 cites W1980755816 @default.
• W2810890325 cites W2005687876 @default.
• W2810890325 cites W2019630276 @default.
• W2810890325 cites W2024986044 @default.
• W2810890325 cites W2033562626 @default.
• W2810890325 cites W2063836318 @default.
• W2810890325 cites W2073815848 @default.
• W2810890325 cites W2074536439 @default.
• W2810890325 cites W2088026293 @default.
• W2810890325 cites W2107337149 @default.
• W2810890325 cites W2126751704 @default.
• W2810890325 cites W2136383818 @default.
• W2810890325 cites W2138375163 @default.
• W2810890325 cites W2168356961 @default.
• W2810890325 cites W2521933461 @default.
• W2810890325 cites W2991190608 @default.
• W2810890325 doi "https://doi.org/10.1016/j.urology.2018.06.022" @default.
• W2810890325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29960004" @default.
• W2810890325 hasPublicationYear "2018" @default.
• W2810890325 type Work @default.
• W2810890325 sameAs 2810890325 @default.
• W2810890325 citedByCount "30" @default.
• W2810890325 countsByYear W28108903252018 @default.
• W2810890325 countsByYear W28108903252019 @default.
• W2810890325 countsByYear W28108903252020 @default.
• W2810890325 countsByYear W28108903252021 @default.
• W2810890325 countsByYear W28108903252022 @default.
• W2810890325 countsByYear W28108903252023 @default.
• W2810890325 crossrefType "journal-article" @default.
• W2810890325 hasAuthorship W2810890325A5011893909 @default.
• W2810890325 hasAuthorship W2810890325A5013809279 @default.
• W2810890325 hasAuthorship W2810890325A5047934585 @default.
• W2810890325 hasAuthorship W2810890325A5054919199 @default.
• W2810890325 hasAuthorship W2810890325A5064680914 @default.
• W2810890325 hasAuthorship W2810890325A5067886311 @default.
• W2810890325 hasAuthorship W2810890325A5070841583 @default.
• W2810890325 hasAuthorship W2810890325A5079539755 @default.
• W2810890325 hasAuthorship W2810890325A5081006357 @default.
• W2810890325 hasAuthorship W2810890325A5082716887 @default.
• W2810890325 hasConcept C121608353 @default.
• W2810890325 hasConcept C126322002 @default.
• W2810890325 hasConcept C197934379 @default.
• W2810890325 hasConcept C2775874879 @default.
• W2810890325 hasConcept C2776235491 @default.
• W2810890325 hasConcept C2777105317 @default.
• W2810890325 hasConcept C2777288759 @default.
• W2810890325 hasConcept C2778093883 @default.
• W2810890325 hasConcept C2778715236 @default.
• W2810890325 hasConcept C2778878792 @default.
• W2810890325 hasConcept C2779929075 @default.
• W2810890325 hasConcept C2780192828 @default.
• W2810890325 hasConcept C71924100 @default.
• W2810890325 hasConceptScore W2810890325C121608353 @default.
• W2810890325 hasConceptScore W2810890325C126322002 @default.
• W2810890325 hasConceptScore W2810890325C197934379 @default.
• W2810890325 hasConceptScore W2810890325C2775874879 @default.
• W2810890325 hasConceptScore W2810890325C2776235491 @default.
• W2810890325 hasConceptScore W2810890325C2777105317 @default.
• W2810890325 hasConceptScore W2810890325C2777288759 @default.
• W2810890325 hasConceptScore W2810890325C2778093883 @default.
• W2810890325 hasConceptScore W2810890325C2778715236 @default.
• W2810890325 hasConceptScore W2810890325C2778878792 @default.
• W2810890325 hasConceptScore W2810890325C2779929075 @default.
• W2810890325 hasConceptScore W2810890325C2780192828 @default.
• W2810890325 hasConceptScore W2810890325C71924100 @default.
• W2810890325 hasLocation W28108903251 @default.
• W2810890325 hasLocation W28108903252 @default.
• W2810890325 hasOpenAccess W2810890325 @default.
• W2810890325 hasPrimaryLocation W28108903251 @default.
• W2810890325 hasRelatedWork W2107337149 @default.
• W2810890325 hasRelatedWork W2157723266 @default.
• W2810890325 hasRelatedWork W2416358393 @default.
• W2810890325 hasRelatedWork W2593339698 @default.
• W2810890325 hasRelatedWork W2611241383 @default.
• W2810890325 hasRelatedWork W2774054421 @default.
• W2810890325 hasRelatedWork W2791184497 @default.
• W2810890325 hasRelatedWork W2801892863 @default.
• W2810890325 hasRelatedWork W2810890325 @default.
• W2810890325 hasRelatedWork W4231314097 @default.
• W2810890325 hasVolume "120" @default.

• next