FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2810911863> ?p ?o ?g. }

• W2810911863 abstract "Abstract A previously reported gene cluster encoding four nisin-like peptides, three with the same sequence (NsoA1-3) and the unique NsoA4, produced antimicrobial activity in the presence of trypsin after heterologous expression in Lactococcus lactis . Protein extracts were separated by SDS gel electrophoresis or immunoprecipitation using an antibody to the NsoA2 leader. Tryptic peptides observed by LC-MS/MS covered the complete sequence of preNsoA1-3 and part of the leader sequence of preNsoA4 and confirmed the expression and the predicted sequences of the preNsoA peptides. Further, the data revealed that the preNsoA1-3 peptides were partly modified with dehydrations and formation of lanthionine rings. A certain amount of fully modified preNsoA1-3 was observed. Details of modifications of the core peptide and the C-terminal tryptic peptide TATCGCHITGK covering rings D and E indicated that 22% of these preNsoA1-3 peptides were completely modified. A lower amount of ring formation is estimated for rings A-C. Intact masses of immunoprecipitation-derived peptides determined by LC-MS accurately matched the expected preNsoA precursor peptides. The most abundant peptides detected were preNsoA2-3-8H 2 O followed by preNsoA1-8H 2 O and other states of dehydration. The results confirm incomplete processing of preNsoA peptides in the heterologous system, with the formation of a certain amount of fully modified peptides." @default.
• W2810911863 created "2018-07-10" @default.
• W2810911863 creator A5023372559 @default.
• W2810911863 creator A5033500678 @default.
• W2810911863 creator A5044358245 @default.
• W2810911863 creator A5045255822 @default.
• W2810911863 creator A5075052988 @default.
• W2810911863 date "2018-07-04" @default.
• W2810911863 modified "2023-10-13" @default.
• W2810911863 title "Processing and Structure of the Lantibiotic Peptide Nso From the Human Gut Bacterium Blautia obeum A2-162 analysed by Mass Spectrometry" @default.
• W2810911863 cites W1506607175 @default.
• W2810911863 cites W1544835748 @default.
• W2810911863 cites W1963494339 @default.
• W2810911863 cites W1967100339 @default.
• W2810911863 cites W1967273004 @default.
• W2810911863 cites W1968051013 @default.
• W2810911863 cites W1971203269 @default.
• W2810911863 cites W1975156465 @default.
• W2810911863 cites W1976117972 @default.
• W2810911863 cites W1982476333 @default.
• W2810911863 cites W1985067765 @default.
• W2810911863 cites W1987063095 @default.
• W2810911863 cites W1991366673 @default.
• W2810911863 cites W1997298634 @default.
• W2810911863 cites W2015869850 @default.
• W2810911863 cites W2042333161 @default.
• W2810911863 cites W2050428291 @default.
• W2810911863 cites W2051531983 @default.
• W2810911863 cites W2080752012 @default.
• W2810911863 cites W2084377454 @default.
• W2810911863 cites W2085805117 @default.
• W2810911863 cites W2090270199 @default.
• W2810911863 cites W2098657755 @default.
• W2810911863 cites W2102302394 @default.
• W2810911863 cites W2112793784 @default.
• W2810911863 cites W2115356798 @default.
• W2810911863 cites W2118573563 @default.
• W2810911863 cites W2118991174 @default.
• W2810911863 cites W2136946582 @default.
• W2810911863 cites W2140967955 @default.
• W2810911863 cites W2142325202 @default.
• W2810911863 cites W2142696585 @default.
• W2810911863 cites W2145267282 @default.
• W2810911863 cites W2151461843 @default.
• W2810911863 cites W2155398486 @default.
• W2810911863 cites W2156392588 @default.
• W2810911863 cites W2160251091 @default.
• W2810911863 cites W2162854463 @default.
• W2810911863 cites W2164760007 @default.
• W2810911863 cites W2165105606 @default.
• W2810911863 cites W2166280629 @default.
• W2810911863 cites W2172046377 @default.
• W2810911863 cites W2233236537 @default.
• W2810911863 cites W2236539978 @default.
• W2810911863 cites W2429194438 @default.
• W2810911863 cites W2514283024 @default.
• W2810911863 cites W2557882133 @default.
• W2810911863 cites W2752625644 @default.
• W2810911863 cites W4234586755 @default.
• W2810911863 cites W4253778685 @default.
• W2810911863 doi "https://doi.org/10.1038/s41598-018-28248-6" @default.
• W2810911863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6031655" @default.
• W2810911863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29973605" @default.
• W2810911863 hasPublicationYear "2018" @default.
• W2810911863 type Work @default.
• W2810911863 sameAs 2810911863 @default.
• W2810911863 citedByCount "6" @default.
• W2810911863 countsByYear W28109118632019 @default.
• W2810911863 countsByYear W28109118632020 @default.
• W2810911863 countsByYear W28109118632022 @default.
• W2810911863 countsByYear W28109118632023 @default.
• W2810911863 crossrefType "journal-article" @default.
• W2810911863 hasAuthorship W2810911863A5023372559 @default.
• W2810911863 hasAuthorship W2810911863A5033500678 @default.
• W2810911863 hasAuthorship W2810911863A5044358245 @default.
• W2810911863 hasAuthorship W2810911863A5045255822 @default.
• W2810911863 hasAuthorship W2810911863A5075052988 @default.
• W2810911863 hasBestOaLocation W28109118631 @default.
• W2810911863 hasConcept C104317684 @default.
• W2810911863 hasConcept C108305142 @default.
• W2810911863 hasConcept C116084860 @default.
• W2810911863 hasConcept C132141352 @default.
• W2810911863 hasConcept C153911025 @default.
• W2810911863 hasConcept C162356407 @default.
• W2810911863 hasConcept C167625842 @default.
• W2810911863 hasConcept C178790620 @default.
• W2810911863 hasConcept C181199279 @default.
• W2810911863 hasConcept C185592680 @default.
• W2810911863 hasConcept C2775920511 @default.
• W2810911863 hasConcept C2778457984 @default.
• W2810911863 hasConcept C2779281246 @default.
• W2810911863 hasConcept C2780011460 @default.
• W2810911863 hasConcept C2780115692 @default.
• W2810911863 hasConcept C2780340462 @default.
• W2810911863 hasConcept C2781192991 @default.
• W2810911863 hasConcept C31827203 @default.
• W2810911863 hasConcept C40767141 @default.
• W2810911863 hasConcept C43617362 @default.
• W2810911863 hasConcept C4937899 @default.
• W2810911863 hasConcept C523546767 @default.

• next