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- W2810971504 abstract "Drug delivery into the eye and enhanced administration of active cosmeceutical ingredients are currently under intense investigation in both academia and industry, while this chapter reviews the increasing investigations of the use of microneedles (MNs) for therapeutic drug monitoring purposes. The ever-increasing amount of fundamental knowledge appears to be feeding industrial development. This chapter shows that suitably formulated dissolving MN platforms can deliver therapeutic doses of a low potency, high dose drug substance. As an MN dosage form will penetrate the stratum corneum into the epidermis, rather than simply adhere to its surface, sterility being a regulatory requirement, although a low bioburden, may be acceptable in cases where the system has inherent and demonstrable antimicrobial activity. Moving towards commercialisation, it is likely that patients will need a level of assurance that the MN device has actually been inserted properly into their skin." @default.
- W2810971504 created "2018-07-10" @default.
- W2810971504 creator A5035668087 @default.
- W2810971504 date "2018-06-22" @default.
- W2810971504 modified "2023-10-16" @default.
- W2810971504 title "Clinical Translation and Industrial Development of Microneedle-based Products" @default.
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- W2810971504 doi "https://doi.org/10.1002/9781119305101.ch11" @default.
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