Matches in SemOpenAlex for { <https://semopenalex.org/work/W2811156665> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2811156665 abstract "Introduction HNSCCs are characterised by distinct phenotypic, aetiological, biological and clinical heterogeneity. It is a heterogeneous disease that can be roughly divided into human papillomavirus (HPV) positive and negative. HPV is a recently identified causative agent for a subset of head and neck cancers, primarily in the oropharynx but very little is known about the prevalence of specific HPV types in Pakistan. Material and methods This cross sectional study was carried out in the Department of Immunology, University of Health Sciences, Lahore, Pakistan after approval from the Ethical Review Committee and Advanced Studies and Research Board, UHS Lahore. After an informed consent, tissue sections from a total of 72 patients with HNSCC were collected. The diagnosis of HNSCC was confirmed again on H and E staining and DNA was extracted from formalin fixed paraffin embedded tissue sections using DNA extraction kit. For the detection of HPV DNA, two universal primer sets GP5/GP6 and MY9/MY11 were used in the polymerase chain reaction. The samples, found to be positive for HPV on PCR, were sequenced for the phylogenetic analysis of HPV. Results and discussions Among 72 cases of HNSCC, only 5 (14.4%) cases were found to be positive for HPV by using universal primers sets. The prevalence of HPV in HNSCC in many international studies from Europe and USA have documented a prevalence of 5%–50% in HNSCC cases. After confirming the presence of HPV in HNSCC cases, positive DNA samples have been transported to a well-known international laboratory for gene sequencing and molecular diagnosis. As soon as possible, we will receive the sequencing data, we will sketch a phylogenetic tree and further subtyping of HPV and the further results will be presented. Conclusion The findings of current study will be helpful in launching public health awareness and future vaccination programs against specific HPV types in Pakistan to lessen the burden of HPV related HNSCC." @default.
- W2811156665 created "2018-07-10" @default.
- W2811156665 creator A5013824448 @default.
- W2811156665 creator A5037121187 @default.
- W2811156665 creator A5040572072 @default.
- W2811156665 creator A5064895950 @default.
- W2811156665 creator A5076687888 @default.
- W2811156665 date "2018-06-01" @default.
- W2811156665 modified "2023-10-17" @default.
- W2811156665 title "PO-080 Prevalence of human papilloma virus and its phylogenetic analysis in patients with head and neck squamous cell carcinoma in pakistan" @default.
- W2811156665 doi "https://doi.org/10.1136/esmoopen-2018-eacr25.608" @default.
- W2811156665 hasPublicationYear "2018" @default.
- W2811156665 type Work @default.
- W2811156665 sameAs 2811156665 @default.
- W2811156665 citedByCount "1" @default.
- W2811156665 countsByYear W28111566652022 @default.
- W2811156665 crossrefType "journal-article" @default.
- W2811156665 hasAuthorship W2811156665A5013824448 @default.
- W2811156665 hasAuthorship W2811156665A5037121187 @default.
- W2811156665 hasAuthorship W2811156665A5040572072 @default.
- W2811156665 hasAuthorship W2811156665A5064895950 @default.
- W2811156665 hasAuthorship W2811156665A5076687888 @default.
- W2811156665 hasBestOaLocation W28111566651 @default.
- W2811156665 hasConcept C104317684 @default.
- W2811156665 hasConcept C121608353 @default.
- W2811156665 hasConcept C126322002 @default.
- W2811156665 hasConcept C137627325 @default.
- W2811156665 hasConcept C142724271 @default.
- W2811156665 hasConcept C143998085 @default.
- W2811156665 hasConcept C159047783 @default.
- W2811156665 hasConcept C178790620 @default.
- W2811156665 hasConcept C185592680 @default.
- W2811156665 hasConcept C193252679 @default.
- W2811156665 hasConcept C2776530083 @default.
- W2811156665 hasConcept C2776833033 @default.
- W2811156665 hasConcept C2777563447 @default.
- W2811156665 hasConcept C49105822 @default.
- W2811156665 hasConcept C54355233 @default.
- W2811156665 hasConcept C71924100 @default.
- W2811156665 hasConcept C78063203 @default.
- W2811156665 hasConcept C86803240 @default.
- W2811156665 hasConceptScore W2811156665C104317684 @default.
- W2811156665 hasConceptScore W2811156665C121608353 @default.
- W2811156665 hasConceptScore W2811156665C126322002 @default.
- W2811156665 hasConceptScore W2811156665C137627325 @default.
- W2811156665 hasConceptScore W2811156665C142724271 @default.
- W2811156665 hasConceptScore W2811156665C143998085 @default.
- W2811156665 hasConceptScore W2811156665C159047783 @default.
- W2811156665 hasConceptScore W2811156665C178790620 @default.
- W2811156665 hasConceptScore W2811156665C185592680 @default.
- W2811156665 hasConceptScore W2811156665C193252679 @default.
- W2811156665 hasConceptScore W2811156665C2776530083 @default.
- W2811156665 hasConceptScore W2811156665C2776833033 @default.
- W2811156665 hasConceptScore W2811156665C2777563447 @default.
- W2811156665 hasConceptScore W2811156665C49105822 @default.
- W2811156665 hasConceptScore W2811156665C54355233 @default.
- W2811156665 hasConceptScore W2811156665C71924100 @default.
- W2811156665 hasConceptScore W2811156665C78063203 @default.
- W2811156665 hasConceptScore W2811156665C86803240 @default.
- W2811156665 hasLocation W28111566651 @default.
- W2811156665 hasOpenAccess W2811156665 @default.
- W2811156665 hasPrimaryLocation W28111566651 @default.
- W2811156665 hasRelatedWork W2017100360 @default.
- W2811156665 hasRelatedWork W2181339103 @default.
- W2811156665 hasRelatedWork W2204147786 @default.
- W2811156665 hasRelatedWork W2253577193 @default.
- W2811156665 hasRelatedWork W2272928823 @default.
- W2811156665 hasRelatedWork W2321783853 @default.
- W2811156665 hasRelatedWork W2325244064 @default.
- W2811156665 hasRelatedWork W2523551656 @default.
- W2811156665 hasRelatedWork W2588335170 @default.
- W2811156665 hasRelatedWork W2599574402 @default.
- W2811156665 hasRelatedWork W2752490298 @default.
- W2811156665 hasRelatedWork W2767724205 @default.
- W2811156665 hasRelatedWork W2768769773 @default.
- W2811156665 hasRelatedWork W2901849855 @default.
- W2811156665 hasRelatedWork W2929979823 @default.
- W2811156665 hasRelatedWork W2975220332 @default.
- W2811156665 hasRelatedWork W3111855480 @default.
- W2811156665 hasRelatedWork W3149685958 @default.
- W2811156665 hasRelatedWork W3158860003 @default.
- W2811156665 hasRelatedWork W3213643000 @default.
- W2811156665 isParatext "false" @default.
- W2811156665 isRetracted "false" @default.
- W2811156665 magId "2811156665" @default.
- W2811156665 workType "article" @default.