FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2811266668> ?p ?o ?g. }

• W2811266668 endingPage "10" @default.
• W2811266668 startingPage "1" @default.
• W2811266668 abstract "For over 40 years, mitochondrial reactive oxygen species (ROS) production and balance has been studied in the context of oxidative distress and tissue damage. However, research over the past decade has demonstrated that the mitochondria have a more complicated relationship with ROS. Superoxide (O 2 •− ) and hydrogen peroxide (H 2 O 2 ) are the proximal ROS formed by the mitochondria, and the latter molecule is used as a secondary messenger to coordinate oxidative metabolism with changes in cell physiology. Like any other secondary messenger, H 2 O 2 levels need to be regulated through its production and degradation and the mitochondria are enriched with the antioxidant defenses required to degrade ROS formed by nutrient oxidation and respiration. Recent work has also demonstrated that these antioxidant systems also carry the capacity to clear H 2 O 2 formed outside of mitochondria. These observations led to the development of the postulate that the mitochondria serve as “ROS stabilizing devices” that buffer cellular H 2 O 2 levels. Here, I provide an updated view on mitochondrial ROS homeostasis and discuss the “ROS stabilizing” function of the mitochondria in mammalian cells. This will be followed by a hypothetical discussion on the potential function of the mitochondria and proton motive force in degrading cellular H 2 O 2 signals emanating from cytosolic enzymes." @default.
• W2811266668 created "2018-07-10" @default.
• W2811266668 creator A5061668188 @default.
• W2811266668 date "2018-07-02" @default.
• W2811266668 modified "2023-10-17" @default.
• W2811266668 title "Mitochondrial Antioxidants and the Maintenance of Cellular Hydrogen Peroxide Levels" @default.
• W2811266668 cites W1594094412 @default.
• W2811266668 cites W1938241710 @default.
• W2811266668 cites W1965923738 @default.
• W2811266668 cites W1966160892 @default.
• W2811266668 cites W1975084717 @default.
• W2811266668 cites W1978048781 @default.
• W2811266668 cites W1987400910 @default.
• W2811266668 cites W1990811092 @default.
• W2811266668 cites W1991634110 @default.
• W2811266668 cites W2001830362 @default.
• W2811266668 cites W2003578107 @default.
• W2811266668 cites W2003996880 @default.
• W2811266668 cites W2008315282 @default.
• W2811266668 cites W2008878041 @default.
• W2811266668 cites W2011124873 @default.
• W2811266668 cites W2011344898 @default.
• W2811266668 cites W2011593105 @default.
• W2811266668 cites W2014538367 @default.
• W2811266668 cites W2016031481 @default.
• W2811266668 cites W2019560775 @default.
• W2811266668 cites W2029144840 @default.
• W2811266668 cites W2030282154 @default.
• W2811266668 cites W2033007699 @default.
• W2811266668 cites W2040947317 @default.
• W2811266668 cites W2043346183 @default.
• W2811266668 cites W2048919781 @default.
• W2811266668 cites W2057208800 @default.
• W2811266668 cites W2057308780 @default.
• W2811266668 cites W2067138633 @default.
• W2811266668 cites W2068866029 @default.
• W2811266668 cites W2069670534 @default.
• W2811266668 cites W2072569792 @default.
• W2811266668 cites W2079310705 @default.
• W2811266668 cites W2084264696 @default.
• W2811266668 cites W2084827362 @default.
• W2811266668 cites W2087350238 @default.
• W2811266668 cites W2112268703 @default.
• W2811266668 cites W2122341467 @default.
• W2811266668 cites W2142251961 @default.
• W2811266668 cites W2143505819 @default.
• W2811266668 cites W2147849026 @default.
• W2811266668 cites W2158496331 @default.
• W2811266668 cites W2158788819 @default.
• W2811266668 cites W2167321414 @default.
• W2811266668 cites W2253625602 @default.
• W2811266668 cites W2316348002 @default.
• W2811266668 cites W2336416528 @default.
• W2811266668 cites W2342194767 @default.
• W2811266668 cites W2415373443 @default.
• W2811266668 cites W2469730409 @default.
• W2811266668 cites W2481948442 @default.
• W2811266668 cites W2514717725 @default.
• W2811266668 cites W2568510753 @default.
• W2811266668 cites W2601394082 @default.
• W2811266668 cites W2613209849 @default.
• W2811266668 cites W2614016715 @default.
• W2811266668 cites W2725933390 @default.
• W2811266668 cites W2747213856 @default.
• W2811266668 cites W2775061962 @default.
• W2811266668 cites W2776746901 @default.
• W2811266668 cites W2792703627 @default.
• W2811266668 doi "https://doi.org/10.1155/2018/7857251" @default.
• W2811266668 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6051038" @default.
• W2811266668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30057684" @default.
• W2811266668 hasPublicationYear "2018" @default.
• W2811266668 type Work @default.
• W2811266668 sameAs 2811266668 @default.
• W2811266668 citedByCount "131" @default.
• W2811266668 countsByYear W28112666682019 @default.
• W2811266668 countsByYear W28112666682020 @default.
• W2811266668 countsByYear W28112666682021 @default.
• W2811266668 countsByYear W28112666682022 @default.
• W2811266668 countsByYear W28112666682023 @default.
• W2811266668 crossrefType "journal-article" @default.
• W2811266668 hasAuthorship W2811266668A5061668188 @default.
• W2811266668 hasBestOaLocation W28112666681 @default.
• W2811266668 hasConcept C151730666 @default.
• W2811266668 hasConcept C181199279 @default.
• W2811266668 hasConcept C185592680 @default.
• W2811266668 hasConcept C2776151105 @default.
• W2811266668 hasConcept C2778004101 @default.
• W2811266668 hasConcept C2778175917 @default.
• W2811266668 hasConcept C2779343474 @default.
• W2811266668 hasConcept C2780795997 @default.
• W2811266668 hasConcept C28859421 @default.
• W2811266668 hasConcept C48349386 @default.
• W2811266668 hasConcept C533411734 @default.
• W2811266668 hasConcept C55493867 @default.
• W2811266668 hasConcept C57600042 @default.
• W2811266668 hasConcept C86803240 @default.
• W2811266668 hasConcept C95444343 @default.
• W2811266668 hasConcept C98539663 @default.

• next