Matches in SemOpenAlex for { <https://semopenalex.org/work/W2811327801> ?p ?o ?g. }
- W2811327801 abstract "1. Abstract Dopaminergic neurons in the brain of the Drosophila larva play a key role in mediating reward information to the mushroom bodies during appetitive olfactory learning and memory. Using optogenetic activation of Kenyon cells we provide evidence that a functional recurrent signaling loop exists between Kenyon cells and dopaminergic neurons of the primary protocerebral anterior (pPAM) cluster. An optogenetic activation of Kenyon cells paired with an odor is sufficient to induce appetitive memory, while a simultaneous impairment of the dopaminergic pPAM neurons abolishes memory expression. Thus, dopaminergic pPAM neurons mediate reward information to the Kenyon cells, but in turn receive feedback from Kenyon cells. We further show that the activation of recurrent signaling routes within mushroom body circuitry increases the persistence of an odor-sugar memory. Our results suggest that sustained activity in a neuronal circuitry is a conserved mechanism in insects and vertebrates to consolidate memories." @default.
- W2811327801 created "2018-07-10" @default.
- W2811327801 creator A5017380876 @default.
- W2811327801 creator A5019692352 @default.
- W2811327801 creator A5020499012 @default.
- W2811327801 creator A5064096739 @default.
- W2811327801 creator A5066837611 @default.
- W2811327801 creator A5085392695 @default.
- W2811327801 creator A5086090685 @default.
- W2811327801 creator A5087244246 @default.
- W2811327801 date "2018-06-27" @default.
- W2811327801 modified "2023-09-23" @default.
- W2811327801 title "Reward signaling in a recurrent circuit of dopaminergic neurons and Kenyon cells" @default.
- W2811327801 cites W1787449105 @default.
- W2811327801 cites W1930392015 @default.
- W2811327801 cites W1966877506 @default.
- W2811327801 cites W1966899959 @default.
- W2811327801 cites W1978480214 @default.
- W2811327801 cites W1980949515 @default.
- W2811327801 cites W1984841747 @default.
- W2811327801 cites W1985878549 @default.
- W2811327801 cites W1992686921 @default.
- W2811327801 cites W1996761102 @default.
- W2811327801 cites W1999857900 @default.
- W2811327801 cites W2000329266 @default.
- W2811327801 cites W2003512266 @default.
- W2811327801 cites W2014603039 @default.
- W2811327801 cites W2028791709 @default.
- W2811327801 cites W2034840220 @default.
- W2811327801 cites W2040631236 @default.
- W2811327801 cites W2043547481 @default.
- W2811327801 cites W2048054368 @default.
- W2811327801 cites W2049729241 @default.
- W2811327801 cites W2050045428 @default.
- W2811327801 cites W2058082904 @default.
- W2811327801 cites W2059222243 @default.
- W2811327801 cites W2076848010 @default.
- W2811327801 cites W2077521370 @default.
- W2811327801 cites W2083646860 @default.
- W2811327801 cites W2084615226 @default.
- W2811327801 cites W2085646726 @default.
- W2811327801 cites W2090527896 @default.
- W2811327801 cites W2090551154 @default.
- W2811327801 cites W2091835225 @default.
- W2811327801 cites W2095057163 @default.
- W2811327801 cites W2105810025 @default.
- W2811327801 cites W2112474181 @default.
- W2811327801 cites W2117672081 @default.
- W2811327801 cites W2117794907 @default.
- W2811327801 cites W2123433096 @default.
- W2811327801 cites W2124303089 @default.
- W2811327801 cites W2129664537 @default.
- W2811327801 cites W2132663430 @default.
- W2811327801 cites W2135843883 @default.
- W2811327801 cites W2159106287 @default.
- W2811327801 cites W2167279371 @default.
- W2811327801 cites W2168414233 @default.
- W2811327801 cites W2168456060 @default.
- W2811327801 cites W2179301060 @default.
- W2811327801 cites W2219709225 @default.
- W2811327801 cites W2253563636 @default.
- W2811327801 cites W2265582734 @default.
- W2811327801 cites W2498934683 @default.
- W2811327801 cites W2536680601 @default.
- W2811327801 cites W2608119090 @default.
- W2811327801 cites W2613567252 @default.
- W2811327801 cites W2619970632 @default.
- W2811327801 cites W2737808707 @default.
- W2811327801 cites W2746844509 @default.
- W2811327801 cites W2774719659 @default.
- W2811327801 cites W2783309950 @default.
- W2811327801 cites W2793333536 @default.
- W2811327801 cites W2803949620 @default.
- W2811327801 doi "https://doi.org/10.1101/357145" @default.
- W2811327801 hasPublicationYear "2018" @default.
- W2811327801 type Work @default.
- W2811327801 sameAs 2811327801 @default.
- W2811327801 citedByCount "0" @default.
- W2811327801 crossrefType "posted-content" @default.
- W2811327801 hasAuthorship W2811327801A5017380876 @default.
- W2811327801 hasAuthorship W2811327801A5019692352 @default.
- W2811327801 hasAuthorship W2811327801A5020499012 @default.
- W2811327801 hasAuthorship W2811327801A5064096739 @default.
- W2811327801 hasAuthorship W2811327801A5066837611 @default.
- W2811327801 hasAuthorship W2811327801A5085392695 @default.
- W2811327801 hasAuthorship W2811327801A5086090685 @default.
- W2811327801 hasAuthorship W2811327801A5087244246 @default.
- W2811327801 hasBestOaLocation W28113278011 @default.
- W2811327801 hasConcept C104317684 @default.
- W2811327801 hasConcept C130959647 @default.
- W2811327801 hasConcept C137183658 @default.
- W2811327801 hasConcept C169760540 @default.
- W2811327801 hasConcept C2776038537 @default.
- W2811327801 hasConcept C2776286997 @default.
- W2811327801 hasConcept C2776985911 @default.
- W2811327801 hasConcept C2778609137 @default.
- W2811327801 hasConcept C2779746338 @default.
- W2811327801 hasConcept C2780104201 @default.
- W2811327801 hasConcept C2780496858 @default.
- W2811327801 hasConcept C50738837 @default.