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- W2811364400 abstract "Abstract The majority of patients with acute decompensated heart failure have volume overload. Hypervolemia often results in renal dysfunction because of increased renal venous pressure, impaired renal autoregulation, and decreased renal blood flow, factors that are associated with increased morbidity and mortality. Sodium retention continues to be the primary contributor to volume overload states. Loop diuretics are inconsistent in their ability to remove total body sodium, resulting in the production of hypotonic urine and worsening neurohormonal activation. In contrast, ultrafiltration (UF) can remove isotonic fluid and therefore more sodium without increasing renin secretion. Conflicting results on the effects of UF in heart failure patients emphasize the challenges of patient selection and establishment of fluid removal targets. Early initiation of UF before failure of loop diuretics and development of the cardiorenal syndrome may provide best outcomes. Blood volume estimation, bioimpedance vector analysis, and biomarkers may aid further in the assessment of congestive status and degree of fluid removal required. This chapter reviews and summarizes treatment options for the management of decompensated heart failure patients and the clinical trials regarding decongestive strategies." @default.
- W2811364400 created "2018-07-10" @default.
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- W2811364400 date "2019-01-01" @default.
- W2811364400 modified "2023-10-14" @default.
- W2811364400 title "Management of Overhydration in Heart Failure Patients" @default.
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- W2811364400 doi "https://doi.org/10.1016/b978-0-323-44942-7.00119-9" @default.
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