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- W2811409212 abstract "Limited data exists on healthcare costs associated with chronic migraine (CM) and episodic migraine (EM) using administrative claims data. To compare the 12-month healthcare costs between patients diagnosed with CM and EM using claims data. This was a retrospective study using 2013-2016 data from a large US health insurer. The sampling frame included patients aged ≥18 years with ≥2 migraine diagnoses (346.xx) at least 30 days apart with the date of the earliest migraine claim between 7/1/14 and 6/30/15 assigned as the index date. Patients were required to be continuously enrolled for 12 months pre/post-index date. Patients with ≥2 CM diagnoses (346.7x) at least 30 days apart were assigned to the diagnosed CM group. The diagnosed EM group consisted of patients with ≥2 non-CM migraine diagnoses (346.xx without 346.7x) and absence of any evidence of CM (i.e. no claim for 346.7x or onabotulinumtoxinA) during the entire study period. The 12-month post-index total direct all-cause costs (total, medical, and pharmacy costs) were compared between the diagnosed CM and EM groups. Generalized linear models controlling for patient age, gender, region, plan type, Elixhauser and other migraine-related comorbidities (mood disorders, pain, allergic rhinitis, irritable bowel syndrome, sleep disorder and epilepsy) were used to estimate adjusted costs. The study included 5,555 diagnosed CM and 34,690 EM patients. After adjusting for the potential confounders, diagnosed CM patients ($22,103) demonstrated significantly higher total direct costs than EM patients ($17,225, p<0.05). Mean adjusted medical costs (CM=$17,265 vs. EM=$14,210) and adjusted pharmacy costs (CM= $4,925 vs. EM= $3,011) were also higher in the diagnosed CM than EM (p<0.05). Diagnosed CM was associated with significantly higher total, medical and prescription costs than the diagnosed EM. Appropriate measures are needed to ensure that CM patients are diagnosed and better managed to reduce overall healthcare costs." @default.
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- W2811409212 date "2018-05-01" @default.
- W2811409212 modified "2023-10-18" @default.
- W2811409212 title "Economic Burden of Diagnosed Chronic Migraine and Diagnosed Episodic Migraine Patients in a Large US Health Insurer’s Population" @default.
- W2811409212 doi "https://doi.org/10.1016/j.jval.2018.04.1417" @default.
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