FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2811422498> ?p ?o ?g. }

• W2811422498 abstract "Hepatitis C virus (HCV) treatment regimens (DAAs) are well tolerated, efficacious but costly. Their high cost and restricted availability, raises concerns about the outcome of treatment in uninsured patients. This study investigated sustained virologic response (SVR) outcomes in a predominately uninsured patient population and completion of four steps along the HCV treatment cascade. A retrospective chart review was conducted to characterize the patient population and analyze covariates to determine association with insurance status, attainment of SVR and progression through the HCV treatment cascade. Out of a total of 216 patients, 154 (71%) were uninsured. Approximately 50% of patients (109 of 216 patients) were male and 57% were Hispanic (123 of 216 patients). Sex, race, ethnicity, treatment compliance, and rates of complications were not associated with insurance status. Insured patients were older (median 60 years vs 57 years, p-value < 0.001) and had higher rates of cirrhosis: 32 out of 62 patients (52%) vs 48 out of 154 patients (31%) (p-value = 0.005). Insured patients were tested for SVR at similar rates as uninsured patients: 84% (52 of 62 patients) vs 81% (125 of 154 patients), respectively. Of those tested for SVR, the cure rate for insured patients was 98% (51 out of 52 patients) compared to 97% (121 out of 125 patients) in the uninsured. Out of those who completed treatment, 177 of 189 (94%) were tested for attainment of SVR. Compliance rates were significantly different between tested and untested patients: 88% (156 of 177 patients) vs 0% (0 of 12 patients), respectively (p-value < 0.001). However, insurance status, race ethnicity, cirrhosis, and complications were not associated with being tested for SVR. These results demonstrate that insured and uninsured patients with chronic HCV infection, with access to patient assistance programs, can be treated and have comparable clinical outcomes. In addition, testing for SVR remains an important obstacle in completion of the HCV treatment cascade. Nevertheless, patient assistance programs remove a significant barrier for treatment access in real-world HCV infected populations." @default.
• W2811422498 created "2018-07-10" @default.
• W2811422498 creator A5003472286 @default.
• W2811422498 creator A5022711470 @default.
• W2811422498 creator A5024337226 @default.
• W2811422498 creator A5032326783 @default.
• W2811422498 creator A5035281714 @default.
• W2811422498 creator A5037593731 @default.
• W2811422498 creator A5042806301 @default.
• W2811422498 creator A5043581009 @default.
• W2811422498 date "2018-06-28" @default.
• W2811422498 modified "2023-09-25" @default.
• W2811422498 title "Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population" @default.
• W2811422498 cites W1758723825 @default.
• W2811422498 cites W1784564451 @default.
• W2811422498 cites W1965636055 @default.
• W2811422498 cites W1967228793 @default.
• W2811422498 cites W1990725691 @default.
• W2811422498 cites W2013824807 @default.
• W2811422498 cites W2037763899 @default.
• W2811422498 cites W2053997784 @default.
• W2811422498 cites W2088457568 @default.
• W2811422498 cites W2122697393 @default.
• W2811422498 cites W2123251487 @default.
• W2811422498 cites W2130047949 @default.
• W2811422498 cites W2140149341 @default.
• W2811422498 cites W2164833599 @default.
• W2811422498 cites W2184924102 @default.
• W2811422498 cites W2311331156 @default.
• W2811422498 cites W2340954406 @default.
• W2811422498 cites W2474774499 @default.
• W2811422498 cites W2530848529 @default.
• W2811422498 cites W2602169852 @default.
• W2811422498 cites W2604002167 @default.
• W2811422498 cites W2611584903 @default.
• W2811422498 cites W2621758394 @default.
• W2811422498 cites W2726614251 @default.
• W2811422498 cites W2735669709 @default.
• W2811422498 cites W2743977148 @default.
• W2811422498 cites W2753756934 @default.
• W2811422498 cites W2768216593 @default.
• W2811422498 cites W971519378 @default.
• W2811422498 doi "https://doi.org/10.1186/s12967-018-1555-y" @default.
• W2811422498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6027772" @default.
• W2811422498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29954391" @default.
• W2811422498 hasPublicationYear "2018" @default.
• W2811422498 type Work @default.
• W2811422498 sameAs 2811422498 @default.
• W2811422498 citedByCount "12" @default.
• W2811422498 countsByYear W28114224982018 @default.
• W2811422498 countsByYear W28114224982019 @default.
• W2811422498 countsByYear W28114224982020 @default.
• W2811422498 countsByYear W28114224982021 @default.
• W2811422498 countsByYear W28114224982022 @default.
• W2811422498 countsByYear W28114224982023 @default.
• W2811422498 crossrefType "journal-article" @default.
• W2811422498 hasAuthorship W2811422498A5003472286 @default.
• W2811422498 hasAuthorship W2811422498A5022711470 @default.
• W2811422498 hasAuthorship W2811422498A5024337226 @default.
• W2811422498 hasAuthorship W2811422498A5032326783 @default.
• W2811422498 hasAuthorship W2811422498A5035281714 @default.
• W2811422498 hasAuthorship W2811422498A5037593731 @default.
• W2811422498 hasAuthorship W2811422498A5042806301 @default.
• W2811422498 hasAuthorship W2811422498A5043581009 @default.
• W2811422498 hasBestOaLocation W28114224981 @default.
• W2811422498 hasConcept C126322002 @default.
• W2811422498 hasConcept C167135981 @default.
• W2811422498 hasConcept C2776455275 @default.
• W2811422498 hasConcept C2777214474 @default.
• W2811422498 hasConcept C2908647359 @default.
• W2811422498 hasConcept C71924100 @default.
• W2811422498 hasConcept C99454951 @default.
• W2811422498 hasConceptScore W2811422498C126322002 @default.
• W2811422498 hasConceptScore W2811422498C167135981 @default.
• W2811422498 hasConceptScore W2811422498C2776455275 @default.
• W2811422498 hasConceptScore W2811422498C2777214474 @default.
• W2811422498 hasConceptScore W2811422498C2908647359 @default.
• W2811422498 hasConceptScore W2811422498C71924100 @default.
• W2811422498 hasConceptScore W2811422498C99454951 @default.
• W2811422498 hasIssue "1" @default.
• W2811422498 hasLocation W28114224981 @default.
• W2811422498 hasLocation W28114224982 @default.
• W2811422498 hasLocation W28114224983 @default.
• W2811422498 hasLocation W28114224984 @default.
• W2811422498 hasLocation W28114224985 @default.
• W2811422498 hasOpenAccess W2811422498 @default.
• W2811422498 hasPrimaryLocation W28114224981 @default.
• W2811422498 hasRelatedWork W2105151527 @default.
• W2811422498 hasRelatedWork W2364009260 @default.
• W2811422498 hasRelatedWork W2380057670 @default.
• W2811422498 hasRelatedWork W2381699712 @default.
• W2811422498 hasRelatedWork W2391842199 @default.
• W2811422498 hasRelatedWork W2896627865 @default.
• W2811422498 hasRelatedWork W3013145321 @default.
• W2811422498 hasRelatedWork W3208090289 @default.
• W2811422498 hasRelatedWork W3210359220 @default.
• W2811422498 hasRelatedWork W4255376461 @default.
• W2811422498 hasVolume "16" @default.
• W2811422498 isParatext "false" @default.
• W2811422498 isRetracted "false" @default.

• next