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- W2811890962 abstract "Cedecea neteri , a member of the Enterobacteriaceae family, has only been identified as a human pathogen in a few previous clinical cases, thus complicating assessment of this organism’s pathogenicity and medical relevance. Documented infections attributed to C. neteri primarily involved bacteremia in severely immunocompromised patients. We report a rare case of urinary catheter colonization by a multidrug-resistant C. neteri strain in a patient of advanced age with benign prostatic hyperplasia and other chronic comorbidities. This C. neteri isolate was resistant or intermediate to second-generation cephalosporins, penicillins, and certain β -lactamase inhibitor/ β -lactam combinations. Analysis of whole genome sequence information for a representative C. neteri strain indicated the presence of multiple open reading frames with sequence similarity to β -lactamases, including a chromosome-encoded AmpC β -lactamase and metallo- β -lactamases, consistent with the resistance phenotype of this bacterium. The presence of an AmpR homolog suggests that the C. neteri ampC may be inducible in response to β -lactam exposure. Molecular insights into antibiotic resistance traits of this emerging opportunistic pathogen will be important for administering adequate antibiotic treatment to ensure favorable patient outcomes." @default.
- W2811890962 created "2018-07-19" @default.
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- W2811890962 date "2018-07-11" @default.
- W2811890962 modified "2023-09-26" @default.
- W2811890962 title "Urinary Catheter Colonization by Multidrug-ResistantCedecea neteriin Patient with Benign Prostatic Hyperplasia" @default.
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- W2811890962 doi "https://doi.org/10.1155/2018/7520527" @default.
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