Matches in SemOpenAlex for { <https://semopenalex.org/work/W2816357797> ?p ?o ?g. }
- W2816357797 abstract "Chronic kidney disease (CKD) poses a substantial health burden in sub-Saharan Africa, with risk factors ranging from communicable to non-communicable diseases. Hyperuricemia has been recently identified as a factor of progression of CKD. Identifying factors associated with hyperuricemia in CKD patients would help determine interventions to reduce CKD mortality, particularly in resources limited countries. We sought to determine the prevalence and factors associated with hyperuricemia in non-dialysed CKD adult patients in Cameroon. This was a cross-sectional study of non-dialysed CKD patients, conducted in 3 referral nephrology units in Cameroon. Relevant clinical and laboratory data were collected using interviewer-administered questionnaires. Serum uric acid, spot urine protein and spot urine creatinine were assessed. Associations between variables were assessed using multivariate analysis. Level of statistical significance was set at α < 0.05. A sample of 103 participants was included. Mean age of study participants was 55.78 ± 12.58 years, and 59.3% were men. Sixty-nine (67%) had hyperuricemia. Patient’s age (OR: 1.08, 95% CI: 1.03–1.13), estimated glomerular filtration rate (OR: 0.94, 95% CI: 0.90–0.98), spot urine protein-creatinine ratio (OR: 1.83, 95% CI: 1.07–3.12), no hypertension (OR: 0.09, 95% CI: 0.02–0.46), urate lowering therapy (OR: 4.99, 95% CI: 1.54–16.16), loop diuretics (OR: 3.39, 95% CI: 1.01–11.42), obesity (OR: 6.12, 95% CI: 1.15–32.55) and no anaemia (OR: 0.04, 95% CI: 0.00–0.29) were independently significantly associated with hyperuricemia. In this sample of non-dialysed CKD patients in Cameroon, about 7 out of 10 had hyperuricemia. Hyperuricemia was independently associated with patient’s age, estimated glomerular filtration rate, spot urine protein-creatinine ratio, hypertension, urate lowering therapy, loop diuretics, obesity and anaemia. More studies are required to establish causal relationships between these associations." @default.
- W2816357797 created "2018-07-19" @default.
- W2816357797 creator A5000055109 @default.
- W2816357797 creator A5018958103 @default.
- W2816357797 creator A5021120505 @default.
- W2816357797 creator A5035513653 @default.
- W2816357797 creator A5081260832 @default.
- W2816357797 date "2018-07-09" @default.
- W2816357797 modified "2023-10-06" @default.
- W2816357797 title "Determinants of hyperuricemia in non-dialysed chronic kidney disease patients in three hospitals in Cameroon" @default.
- W2816357797 cites W1974759427 @default.
- W2816357797 cites W1983490415 @default.
- W2816357797 cites W1985352243 @default.
- W2816357797 cites W1991700740 @default.
- W2816357797 cites W1993336979 @default.
- W2816357797 cites W1998310232 @default.
- W2816357797 cites W2000166484 @default.
- W2816357797 cites W2000821346 @default.
- W2816357797 cites W2008159757 @default.
- W2816357797 cites W2026833252 @default.
- W2816357797 cites W2028058714 @default.
- W2816357797 cites W2053336246 @default.
- W2816357797 cites W2056189241 @default.
- W2816357797 cites W2061170857 @default.
- W2816357797 cites W2089357919 @default.
- W2816357797 cites W2090450375 @default.
- W2816357797 cites W2093768727 @default.
- W2816357797 cites W2104681259 @default.
- W2816357797 cites W2105044392 @default.
- W2816357797 cites W2107804514 @default.
- W2816357797 cites W2111277253 @default.
- W2816357797 cites W2113760558 @default.
- W2816357797 cites W2115546532 @default.
- W2816357797 cites W2117632163 @default.
- W2816357797 cites W2122730408 @default.
- W2816357797 cites W2122753501 @default.
- W2816357797 cites W2122983268 @default.
- W2816357797 cites W2133169646 @default.
- W2816357797 cites W2150856828 @default.
- W2816357797 cites W2151834039 @default.
- W2816357797 cites W2152489539 @default.
- W2816357797 cites W2155965977 @default.
- W2816357797 cites W2156997248 @default.
- W2816357797 cites W2158088707 @default.
- W2816357797 cites W2159843374 @default.
- W2816357797 cites W2161388781 @default.
- W2816357797 cites W2168192831 @default.
- W2816357797 cites W2286212946 @default.
- W2816357797 cites W2319846471 @default.
- W2816357797 cites W2346277594 @default.
- W2816357797 cites W2417131484 @default.
- W2816357797 cites W2547785340 @default.
- W2816357797 cites W2575402762 @default.
- W2816357797 cites W2581021585 @default.
- W2816357797 cites W2592043306 @default.
- W2816357797 cites W2607031541 @default.
- W2816357797 cites W2991008137 @default.
- W2816357797 cites W346031989 @default.
- W2816357797 cites W4230870013 @default.
- W2816357797 cites W4251743604 @default.
- W2816357797 cites W4302766818 @default.
- W2816357797 cites W2112610608 @default.
- W2816357797 doi "https://doi.org/10.1186/s12882-018-0959-5" @default.
- W2816357797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6038336" @default.
- W2816357797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29986666" @default.
- W2816357797 hasPublicationYear "2018" @default.
- W2816357797 type Work @default.
- W2816357797 sameAs 2816357797 @default.
- W2816357797 citedByCount "9" @default.
- W2816357797 countsByYear W28163577972019 @default.
- W2816357797 countsByYear W28163577972020 @default.
- W2816357797 countsByYear W28163577972021 @default.
- W2816357797 countsByYear W28163577972022 @default.
- W2816357797 countsByYear W28163577972023 @default.
- W2816357797 crossrefType "journal-article" @default.
- W2816357797 hasAuthorship W2816357797A5000055109 @default.
- W2816357797 hasAuthorship W2816357797A5018958103 @default.
- W2816357797 hasAuthorship W2816357797A5021120505 @default.
- W2816357797 hasAuthorship W2816357797A5035513653 @default.
- W2816357797 hasAuthorship W2816357797A5081260832 @default.
- W2816357797 hasBestOaLocation W28163577971 @default.
- W2816357797 hasConcept C126322002 @default.
- W2816357797 hasConcept C159641895 @default.
- W2816357797 hasConcept C2778653478 @default.
- W2816357797 hasConcept C2779721657 @default.
- W2816357797 hasConcept C2779881121 @default.
- W2816357797 hasConcept C2780306776 @default.
- W2816357797 hasConcept C2780402116 @default.
- W2816357797 hasConcept C54847362 @default.
- W2816357797 hasConcept C71924100 @default.
- W2816357797 hasConceptScore W2816357797C126322002 @default.
- W2816357797 hasConceptScore W2816357797C159641895 @default.
- W2816357797 hasConceptScore W2816357797C2778653478 @default.
- W2816357797 hasConceptScore W2816357797C2779721657 @default.
- W2816357797 hasConceptScore W2816357797C2779881121 @default.
- W2816357797 hasConceptScore W2816357797C2780306776 @default.
- W2816357797 hasConceptScore W2816357797C2780402116 @default.
- W2816357797 hasConceptScore W2816357797C54847362 @default.
- W2816357797 hasConceptScore W2816357797C71924100 @default.
- W2816357797 hasIssue "1" @default.