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• W2820736783 abstract "A series of novel 6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives were obtained in good yields from ethyl 4,4,4-trifluoro-3-oxobutanoate, urea, and aryl aldehyde via Biginelli multicomponent reaction. All the corresponding products 4a–4p were examined against four human cancer cell lines (A549, HepG2, COLO205 and DU145) and compounds 4e, 4i, and 4 m which showed promising anticancer activity have been identified." @default.
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• W2820736783 date "2018-07-11" @default.
• W2820736783 modified "2023-09-27" @default.
• W2820736783 title "Multicomponent synthesis and anticancer activity studies of novel 6-(Trifluoromethyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives" @default.
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• W2820736783 doi "https://doi.org/10.1080/00397911.2018.1490769" @default.
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