FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W282167316> ?p ?o ?g. }

• W282167316 abstract "There are limited data concerning the assessment of renal function in beta-thalassaemia major, with no study of such involvement in Omani patients. The objective of this study was to establish the pattern of renal glomerular and tubular function using traditional and specific laboratory tests in patients with beta-thalassaemia major.This cross-sectional study, from January-July 2008, included 30 patients of the Thalassaemia Clinic at the Royal Hospital, Oman, with transfusion-dependent homozygous beta-thalassaemia major. They included 15 males and 15 females, aged 16-32 years with mean ± standard deviation of 21.23 ± 3.42 years. The medical records were reviewed and renal function states assessed as follows: serum creatinine, estimated glomerular filtration rate (eGFR); urea; phosphate, fractional excretion of filtered sodium (FENa); urine albumin: creatinine index; urine ß2-microglobulin:creatinine index; tubular reabsorption of phosphate (TRP), and tubular maximum phosphate reabsorption (TmP)/GFR.All patients had eGFR >90 ml/min/1.73m(2); serum creatinine <90 μmol/L; serum urea <6.0 mmol/L, and urine albumin:creatinine <2.5 mg/mmol. Only 2 (6.7%) patients had FENa >1% and 3 (10.0%) patients had urine ß2-microglobulin: creatinine >22 μg/mmol. All patients had TRP >0.85, of whom seven (23.3%) patients had values within the range of 0.85-0.95 and 23 (76.7%) had values >0.95. Also, all patients had TmP/GFR >1.0 mmol/L, of whom only one (3.3%) patient had TmP/GFR of 1.0-1.5, and 29 (96.7%) patients had TmP/GFR >1.5 mmol/L. Finally, 24 (80%) patients had serum phosphate >1.4 mmol/L. Linear regression revealed a highly significant correlation between serum phosphate and TmP/GFR (r = 0.904, P < 0.001).Renal function, glomerular and tubular, appears to be well preserved in beta-thalassaemia major. Almost all renal function indicators were within the recommended ranges. Raised TmP/GFR and TRP were noted in the majority of patients, reflecting an up-trend in serum phosphate and therefore increasing renal phosphate reabsorption." @default.
• W282167316 created "2016-06-24" @default.
• W282167316 creator A5052388740 @default.
• W282167316 creator A5056041220 @default.
• W282167316 creator A5089019636 @default.
• W282167316 date "2011-02-01" @default.
• W282167316 modified "2023-09-23" @default.
• W282167316 title "Indicators of Renal Glomerular and Tubular Functions in Patients with Beta-Thalassaemia Major: A cross sectional study at the Royal Hospital, Oman." @default.
• W282167316 cites W1256414386 @default.
• W282167316 cites W1494987057 @default.
• W282167316 cites W1506960804 @default.
• W282167316 cites W1533580110 @default.
• W282167316 cites W1970529990 @default.
• W282167316 cites W2013088777 @default.
• W282167316 cites W2013316106 @default.
• W282167316 cites W2018173221 @default.
• W282167316 cites W2032840992 @default.
• W282167316 cites W2057721700 @default.
• W282167316 cites W2072050034 @default.
• W282167316 cites W2075973272 @default.
• W282167316 cites W2078752932 @default.
• W282167316 cites W2079360448 @default.
• W282167316 cites W2116274364 @default.
• W282167316 cites W2121809836 @default.
• W282167316 cites W2123831918 @default.
• W282167316 cites W2125289626 @default.
• W282167316 cites W2125610771 @default.
• W282167316 cites W2130635040 @default.
• W282167316 cites W2138727312 @default.
• W282167316 cites W2139473795 @default.
• W282167316 cites W2317072972 @default.
• W282167316 cites W2324042292 @default.
• W282167316 cites W2408287905 @default.
• W282167316 cites W2411383273 @default.
• W282167316 cites W2412675120 @default.
• W282167316 cites W2418263601 @default.
• W282167316 cites W85496010 @default.
• W282167316 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3074678" @default.
• W282167316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21509211" @default.
• W282167316 hasPublicationYear "2011" @default.
• W282167316 type Work @default.
• W282167316 sameAs 282167316 @default.
• W282167316 citedByCount "5" @default.
• W282167316 countsByYear W2821673162012 @default.
• W282167316 countsByYear W2821673162013 @default.
• W282167316 countsByYear W2821673162018 @default.
• W282167316 countsByYear W2821673162020 @default.
• W282167316 crossrefType "journal-article" @default.
• W282167316 hasAuthorship W282167316A5052388740 @default.
• W282167316 hasAuthorship W282167316A5056041220 @default.
• W282167316 hasAuthorship W282167316A5089019636 @default.
• W282167316 hasConcept C126322002 @default.
• W282167316 hasConcept C142052008 @default.
• W282167316 hasConcept C142724271 @default.
• W282167316 hasConcept C159641895 @default.
• W282167316 hasConcept C187212893 @default.
• W282167316 hasConcept C2777799968 @default.
• W282167316 hasConcept C2909410647 @default.
• W282167316 hasConcept C71924100 @default.
• W282167316 hasConceptScore W282167316C126322002 @default.
• W282167316 hasConceptScore W282167316C142052008 @default.
• W282167316 hasConceptScore W282167316C142724271 @default.
• W282167316 hasConceptScore W282167316C159641895 @default.
• W282167316 hasConceptScore W282167316C187212893 @default.
• W282167316 hasConceptScore W282167316C2777799968 @default.
• W282167316 hasConceptScore W282167316C2909410647 @default.
• W282167316 hasConceptScore W282167316C71924100 @default.
• W282167316 hasLocation W2821673161 @default.
• W282167316 hasOpenAccess W282167316 @default.
• W282167316 hasPrimaryLocation W2821673161 @default.
• W282167316 hasRelatedWork W2057721700 @default.
• W282167316 hasRelatedWork W2071696806 @default.
• W282167316 isParatext "false" @default.
• W282167316 isRetracted "false" @default.
• W282167316 magId "282167316" @default.
• W282167316 workType "article" @default.