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- W2823593913 abstract "Segmented flow microfluidics has attracted considerable attention owing to the excellent controllability of reaction environment. However, the accurate and stepwise addition of other reactants into the formed droplets/slugs in segmented flow is extraordinarily challenging to achieve, especially for performing particle growth and crystallization processes. Herein, we employed a segmented flow microchannel with passive picoinjection to realize the accurate addition of reactants and continuous particle manufacturing. A Venturi junction was integrated into the microchannel to control the injection volume without external power. Rapid mixing for the preparation of BaSO 4 nanoparticles with an average size of 30–40 nm, multiple injection for the growth of Au nanoparticles from 32 to 91 nm, and continuous crystallization of vaterite CaCO 3 with a high crystal purity were all successfully performed in this microchannel. The feasibility of long‐term operation and large‐scale production of particles by combining with droplet splitting was also experimentally verified. © 2018 American Institute of Chemical Engineers AIChE J , 64: 3817–3825, 2018" @default.
- W2823593913 created "2018-07-19" @default.
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- W2823593913 date "2018-07-24" @default.
- W2823593913 modified "2023-10-18" @default.
- W2823593913 title "Controllability and flexibility in particle manufacturing of a segmented microfluidic device with passive picoinjection" @default.
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- W2823593913 doi "https://doi.org/10.1002/aic.16356" @default.
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