Matches in SemOpenAlex for { <https://semopenalex.org/work/W2825332316> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2825332316 endingPage "1293" @default.
- W2825332316 startingPage "1289" @default.
- W2825332316 abstract "Following the tremendous development of hydrogels for cell therapy, there is now a growing need for surgical techniques to validate in vivo scaffold benefits for islet transplantation. Therefore, we propose a newly designed surgical procedure involving the injection of hydrogel-embedded pancreatic islets in the omentum, which is considered a favorable environment for cell survival and function. Our technique, called h-Omental Matrix Islet filliNG (hOMING) was designed to test the benefits of hydrogel on islet survival and function in vivo. Islets were implanted in the omentum of diabetic rats using the hOMING technique and alginate as an islet carrier. Blood glucose and C-peptide levels were recorded to assess graft function. After 2 months, grafts were explanted and studied using insulin and vessel staining. All rats that underwent hOMING exhibited graft function characterized by a glycemia decrease and a C-peptidemia increase ( P < 0.001 compared with preoperative levels). Furthermore, hOMING appeared to preserve islet morphology and insulin content and allowed the proper revascularization of grafted islets. The results suggest that hOMING is a viable and promising approach to test in vivo the benefits of hydrogel administration for islet transplantation into the omental tissue." @default.
- W2825332316 created "2018-07-19" @default.
- W2825332316 creator A5003623886 @default.
- W2825332316 creator A5025586948 @default.
- W2825332316 creator A5043506363 @default.
- W2825332316 creator A5050564750 @default.
- W2825332316 creator A5051988881 @default.
- W2825332316 creator A5061243273 @default.
- W2825332316 creator A5072856154 @default.
- W2825332316 creator A5081367683 @default.
- W2825332316 creator A5083557772 @default.
- W2825332316 date "2018-07-11" @default.
- W2825332316 modified "2023-10-16" @default.
- W2825332316 title "Extra-Hepatic Islet Transplantation" @default.
- W2825332316 cites W1123812508 @default.
- W2825332316 cites W1985914247 @default.
- W2825332316 cites W1993976433 @default.
- W2825332316 cites W2039118241 @default.
- W2825332316 cites W2103774499 @default.
- W2825332316 cites W2124025841 @default.
- W2825332316 cites W2126956733 @default.
- W2825332316 cites W2132366902 @default.
- W2825332316 cites W2468880389 @default.
- W2825332316 cites W2573535579 @default.
- W2825332316 cites W2594860963 @default.
- W2825332316 cites W2726804313 @default.
- W2825332316 doi "https://doi.org/10.1177/0963689718784873" @default.
- W2825332316 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6434471" @default.
- W2825332316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29996661" @default.
- W2825332316 hasPublicationYear "2018" @default.
- W2825332316 type Work @default.
- W2825332316 sameAs 2825332316 @default.
- W2825332316 citedByCount "6" @default.
- W2825332316 countsByYear W28253323162020 @default.
- W2825332316 countsByYear W28253323162022 @default.
- W2825332316 countsByYear W28253323162023 @default.
- W2825332316 crossrefType "journal-article" @default.
- W2825332316 hasAuthorship W2825332316A5003623886 @default.
- W2825332316 hasAuthorship W2825332316A5025586948 @default.
- W2825332316 hasAuthorship W2825332316A5043506363 @default.
- W2825332316 hasAuthorship W2825332316A5050564750 @default.
- W2825332316 hasAuthorship W2825332316A5051988881 @default.
- W2825332316 hasAuthorship W2825332316A5061243273 @default.
- W2825332316 hasAuthorship W2825332316A5072856154 @default.
- W2825332316 hasAuthorship W2825332316A5081367683 @default.
- W2825332316 hasAuthorship W2825332316A5083557772 @default.
- W2825332316 hasBestOaLocation W28253323161 @default.
- W2825332316 hasConcept C126322002 @default.
- W2825332316 hasConcept C150903083 @default.
- W2825332316 hasConcept C151872237 @default.
- W2825332316 hasConcept C165220095 @default.
- W2825332316 hasConcept C18903297 @default.
- W2825332316 hasConcept C207001950 @default.
- W2825332316 hasConcept C2779306644 @default.
- W2825332316 hasConcept C2779855799 @default.
- W2825332316 hasConcept C2911091166 @default.
- W2825332316 hasConcept C71924100 @default.
- W2825332316 hasConcept C86803240 @default.
- W2825332316 hasConceptScore W2825332316C126322002 @default.
- W2825332316 hasConceptScore W2825332316C150903083 @default.
- W2825332316 hasConceptScore W2825332316C151872237 @default.
- W2825332316 hasConceptScore W2825332316C165220095 @default.
- W2825332316 hasConceptScore W2825332316C18903297 @default.
- W2825332316 hasConceptScore W2825332316C207001950 @default.
- W2825332316 hasConceptScore W2825332316C2779306644 @default.
- W2825332316 hasConceptScore W2825332316C2779855799 @default.
- W2825332316 hasConceptScore W2825332316C2911091166 @default.
- W2825332316 hasConceptScore W2825332316C71924100 @default.
- W2825332316 hasConceptScore W2825332316C86803240 @default.
- W2825332316 hasIssue "8" @default.
- W2825332316 hasLocation W28253323161 @default.
- W2825332316 hasLocation W28253323162 @default.
- W2825332316 hasLocation W28253323163 @default.
- W2825332316 hasLocation W28253323164 @default.
- W2825332316 hasOpenAccess W2825332316 @default.
- W2825332316 hasPrimaryLocation W28253323161 @default.
- W2825332316 hasRelatedWork W1973049774 @default.
- W2825332316 hasRelatedWork W1985077083 @default.
- W2825332316 hasRelatedWork W1985965417 @default.
- W2825332316 hasRelatedWork W1986775667 @default.
- W2825332316 hasRelatedWork W2012430287 @default.
- W2825332316 hasRelatedWork W2025398748 @default.
- W2825332316 hasRelatedWork W2030768859 @default.
- W2825332316 hasRelatedWork W2064538767 @default.
- W2825332316 hasRelatedWork W2091226888 @default.
- W2825332316 hasRelatedWork W2825332316 @default.
- W2825332316 hasVolume "27" @default.
- W2825332316 isParatext "false" @default.
- W2825332316 isRetracted "false" @default.
- W2825332316 magId "2825332316" @default.
- W2825332316 workType "article" @default.