Matches in SemOpenAlex for { <https://semopenalex.org/work/W28257925> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W28257925 startingPage "1" @default.
- W28257925 abstract "Biosimilars have tremendous potential to reduce the costs of biologic therapies. Emerging markets may represent a significant fraction of future biosimilar production, development, and consumption. Yet safety concerns, price sensitivity, and lower quality standards represent challenges to public health in emerging markets. Well-crafted public-private partnerships between public health agencies, local biosimilar manufacturers, and global pharmaceutical firms that leverage advantages of each can result in biosimilar production targeted to local public health needs using a safety-focused infrastructure. The key clinical risk for biosimilars— immunogenicity—can be addressed by leveraging patient safety tools and incentivizing local producers to work with global drug firms and local public health departments, while technical expertise in large scale current Good Manufacturing Practices (“cGMP”) can be provided by global drug firms. Once this infrastructure is in place, public health departments in partnership with their local and global producers can provide incentives, such as limited market exclusivity, to produce drugs in these emerging markets at higher than required levels (i.e., at or above cGMP). They can also target specific immunotherapies relevant for that particular community’s needs. By doing so, global firms, local producers, and local public health departments can provide direction and improved quality and safety so benefits can inure directly to these populations. Moreover, as global populations begin to rely on these emerging market-produced drugs, greater access, sustainability and affordability may also be promoted. * Department of Anesthesiology, University of California, San Diego School of Medicine, San Diego, CA; San Diego Center for Patient Safety, University of California, San Diego School of Medicine, San Diego, CA; Program in Health Policy, University of California, San Diego, San Diego, CA. This project was internally funded. This manuscript has been seen by all authors, who have approved its content. The authors declare no potential conflicts of interest or competing interests associated with this manuscript. With respect to author contributions, Tim Mackey (TM) and Bryan A. Liang (BAL) jointly conceived the study, TM and BAL jointly wrote the manuscript, TM, and BAL jointly edited the manuscript, and BAL supervised its legal and policy analysis. 2014 PUBLIC-PRIVATE PARTNERSHIPS AND BIOSIMILARS 2 IN EMERGING MARKETS" @default.
- W28257925 created "2016-06-24" @default.
- W28257925 creator A5011830859 @default.
- W28257925 creator A5035342147 @default.
- W28257925 date "2014-05-01" @default.
- W28257925 modified "2023-09-27" @default.
- W28257925 title "Public-Private Partnerships to Promote Biosimilar Access, Affordability, and Patient Safety in Emerging Markets" @default.
- W28257925 hasPublicationYear "2014" @default.
- W28257925 type Work @default.
- W28257925 sameAs 28257925 @default.
- W28257925 citedByCount "1" @default.
- W28257925 countsByYear W282579252020 @default.
- W28257925 crossrefType "journal-article" @default.
- W28257925 hasAuthorship W28257925A5011830859 @default.
- W28257925 hasAuthorship W28257925A5035342147 @default.
- W28257925 hasConcept C10138342 @default.
- W28257925 hasConcept C121087249 @default.
- W28257925 hasConcept C126322002 @default.
- W28257925 hasConcept C138816342 @default.
- W28257925 hasConcept C144133560 @default.
- W28257925 hasConcept C159110408 @default.
- W28257925 hasConcept C160735492 @default.
- W28257925 hasConcept C162324750 @default.
- W28257925 hasConcept C175444787 @default.
- W28257925 hasConcept C2779328685 @default.
- W28257925 hasConcept C29122968 @default.
- W28257925 hasConcept C50522688 @default.
- W28257925 hasConcept C59491497 @default.
- W28257925 hasConcept C71750763 @default.
- W28257925 hasConcept C71924100 @default.
- W28257925 hasConceptScore W28257925C10138342 @default.
- W28257925 hasConceptScore W28257925C121087249 @default.
- W28257925 hasConceptScore W28257925C126322002 @default.
- W28257925 hasConceptScore W28257925C138816342 @default.
- W28257925 hasConceptScore W28257925C144133560 @default.
- W28257925 hasConceptScore W28257925C159110408 @default.
- W28257925 hasConceptScore W28257925C160735492 @default.
- W28257925 hasConceptScore W28257925C162324750 @default.
- W28257925 hasConceptScore W28257925C175444787 @default.
- W28257925 hasConceptScore W28257925C2779328685 @default.
- W28257925 hasConceptScore W28257925C29122968 @default.
- W28257925 hasConceptScore W28257925C50522688 @default.
- W28257925 hasConceptScore W28257925C59491497 @default.
- W28257925 hasConceptScore W28257925C71750763 @default.
- W28257925 hasConceptScore W28257925C71924100 @default.
- W28257925 hasIssue "1" @default.
- W28257925 hasLocation W282579251 @default.
- W28257925 hasOpenAccess W28257925 @default.
- W28257925 hasPrimaryLocation W282579251 @default.
- W28257925 hasRelatedWork W1511279008 @default.
- W28257925 hasRelatedWork W1865263653 @default.
- W28257925 hasRelatedWork W1944059771 @default.
- W28257925 hasRelatedWork W1964943585 @default.
- W28257925 hasRelatedWork W1991519241 @default.
- W28257925 hasRelatedWork W2076229192 @default.
- W28257925 hasRelatedWork W2078049731 @default.
- W28257925 hasRelatedWork W2115571387 @default.
- W28257925 hasRelatedWork W2117723353 @default.
- W28257925 hasRelatedWork W2125844096 @default.
- W28257925 hasRelatedWork W2231304743 @default.
- W28257925 hasRelatedWork W2398134517 @default.
- W28257925 hasRelatedWork W2621826230 @default.
- W28257925 hasRelatedWork W2807392443 @default.
- W28257925 hasRelatedWork W2888795242 @default.
- W28257925 hasRelatedWork W2990396983 @default.
- W28257925 hasRelatedWork W3003303397 @default.
- W28257925 hasRelatedWork W3026011203 @default.
- W28257925 hasRelatedWork W3154594893 @default.
- W28257925 hasRelatedWork W3204807569 @default.
- W28257925 hasVolume "7" @default.
- W28257925 isParatext "false" @default.
- W28257925 isRetracted "false" @default.
- W28257925 magId "28257925" @default.
- W28257925 workType "article" @default.