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• W28306045 abstract "Publisher Summary This chapter discusses motor unit activity in motor disorders. Routine electromyographic examinations of human muscles contribute little to the understanding of motor unit activity in normal and diseased muscle. Few studies have been devoted to the examination of motor unit properties of patients with motor disorders. This situation is surprising because changes in motor unit activity in various motor disturbances hold considerable promise of providing information about their pathophysiology. Because any motor disorder must be associated with changes of motor unit activity, its examination should be diagnostically useful. Any muscle weakness not caused by damage to the contractile mechanisms must be the consequence of a disturbance of neuronal activities in the final common path. Recruitment and firing rate modulation are the two neural force-generating mechanisms. Any neurogenic paresis, whether central or peripheral in origin, must be associated with a disturbance of one or both of these mechanisms. There are two aspects to the recruitment of motor units: (1) the recruitment order and (2) the number of units recruited for a particular muscle action. The orderly recruitment of motoneurons according to size that was first described for animals has been confirmed for human motor units on the basis of correlating the threshold force of recruitment with the motor unit twitch tension or nerve conduction velocity. The examination of a number of lower and upper motoneuron disorders and myopathies has shown that the order of recruitment remains preserved under these pathologic conditions. In contrast to recruitment order, the number of motor units recruited for a particular muscle action cannot be estimated by electromyographic methods. The same is true for the assessment of firing rate modulation." @default.
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• W28306045 date "1984-01-01" @default.
• W28306045 modified "2023-09-26" @default.
• W28306045 title "Motor Unit Activity in Motor Disorders" @default.
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• W28306045 doi "https://doi.org/10.1016/b978-0-409-95144-8.50007-0" @default.
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