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• W2830994668 abstract "Nine new polyoxypregnane glycosides, obcordatas A-I (1–9), were isolated from Aspidopterys obcordata Hemsl vines. Their structures were elucidated by extensive spectroscopic methods. Separated compounds were evaluated for antitumor activities against the human cancer cell lines AGS, SW480, HuH-7 and MCF-7, and compounds 1–6 and 9 showed selective cytotoxicity against HuH-7 cells with IC50 values of 8.7, 10.2, 7.5, 12.1, 16.5, 14.3, and 17.4 μM, respectively. Flow cytometry experiments showed that the effects of compound 1 on the cell cycle were attributable to cell cycle arrest at G1/S phase." @default.
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• W2830994668 date "2018-09-01" @default.
• W2830994668 modified "2023-10-11" @default.
• W2830994668 title "New polyoxypregnane glycosides from Aspidopterys obcordata vines with antitumor activity" @default.
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• W2830994668 doi "https://doi.org/10.1016/j.fitote.2018.07.003" @default.
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