FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2833146385> ?p ?o ?g. }

• W2833146385 endingPage "21" @default.
• W2833146385 startingPage "8" @default.
• W2833146385 abstract "Metabolic syndrome (MetS) is associated with osteoporosis due to the underlying inflammatory and hormonal changes. Annatto tocotrienol has been shown to improve medical complications associated with MetS or bone loss in animal studies. This study aimed to investigate the effects of annatto tocotrienol as a single treatment for MetS and osteoporosis in high-carbohydrate high-fat (HCHF) diet-induced MetS animals. Three-month-old male Wistar rats were randomly divided into five groups. The baseline group was euthanized at the onset of the study. The normal group received standard rat chow and tap water. The remaining groups received HCHF diet and treated with three different regimens orally daily: (a) tocopherol-stripped corn oil (the vehicle of tocotrienol), (b) 60 mg/kg annatto tocotrienol, and (c) 100 mg/kg annatto tocotrienol. At the end of the study, measurements of MetS parameters, body compositions, and bone mineral density were performed in animals before sacrifice. Upon euthanasia, blood and femur of the rats were harvested for the evaluations of bone microstructure, biomechanical strength, remodelling activities, hormonal changes, and inflammatory response. Treatment with annatto tocotrienol improved all MetS parameters (except abdominal obesity), trabecular bone microstructure, bone strength, increased osteoclast number, normalized hormonal changes and inflammatory response in the HCHF animals. In conclusion, annatto tocotrienol is a potential agent for managing MetS and osteoporosis concurrently. The beneficial effects of annatto tocotrienol may be attributed to its ability to prevent the hormonal changes and pro-inflammatory state in animals with MetS." @default.
• W2833146385 created "2018-07-19" @default.
• W2833146385 creator A5004770379 @default.
• W2833146385 creator A5034217467 @default.
• W2833146385 creator A5042383355 @default.
• W2833146385 creator A5060302747 @default.
• W2833146385 creator A5080542506 @default.
• W2833146385 date "2018-11-01" @default.
• W2833146385 modified "2023-10-15" @default.
• W2833146385 title "Exploring the potential of tocotrienol from Bixa orellana as a single agent targeting metabolic syndrome and bone loss" @default.
• W2833146385 cites W1577363347 @default.
• W2833146385 cites W1963690512 @default.
• W2833146385 cites W1965172675 @default.
• W2833146385 cites W1965774172 @default.
• W2833146385 cites W1966215425 @default.
• W2833146385 cites W1968290606 @default.
• W2833146385 cites W1968571694 @default.
• W2833146385 cites W1971400919 @default.
• W2833146385 cites W1978804351 @default.
• W2833146385 cites W1980064638 @default.
• W2833146385 cites W1984317788 @default.
• W2833146385 cites W1986665655 @default.
• W2833146385 cites W1991454458 @default.
• W2833146385 cites W1996022176 @default.
• W2833146385 cites W2003298815 @default.
• W2833146385 cites W2017206122 @default.
• W2833146385 cites W2020673982 @default.
• W2833146385 cites W2021584281 @default.
• W2833146385 cites W2023661484 @default.
• W2833146385 cites W2030791079 @default.
• W2833146385 cites W2036139926 @default.
• W2833146385 cites W2039538197 @default.
• W2833146385 cites W2040600867 @default.
• W2833146385 cites W2045182556 @default.
• W2833146385 cites W2046882967 @default.
• W2833146385 cites W2049965571 @default.
• W2833146385 cites W2051043424 @default.
• W2833146385 cites W2053740873 @default.
• W2833146385 cites W2057071464 @default.
• W2833146385 cites W2061735297 @default.
• W2833146385 cites W2064526045 @default.
• W2833146385 cites W2067875627 @default.
• W2833146385 cites W2068560722 @default.
• W2833146385 cites W2072973376 @default.
• W2833146385 cites W2072992683 @default.
• W2833146385 cites W2076519644 @default.
• W2833146385 cites W2077689041 @default.
• W2833146385 cites W2086358274 @default.
• W2833146385 cites W2088284150 @default.
• W2833146385 cites W2088704959 @default.
• W2833146385 cites W2090050473 @default.
• W2833146385 cites W2095238078 @default.
• W2833146385 cites W2113805413 @default.
• W2833146385 cites W2117526766 @default.
• W2833146385 cites W2120293565 @default.
• W2833146385 cites W2122587719 @default.
• W2833146385 cites W2132572939 @default.
• W2833146385 cites W2132681327 @default.
• W2833146385 cites W2133514604 @default.
• W2833146385 cites W2143104968 @default.
• W2833146385 cites W2144446462 @default.
• W2833146385 cites W2152099215 @default.
• W2833146385 cites W2159169229 @default.
• W2833146385 cites W2166375385 @default.
• W2833146385 cites W2230725582 @default.
• W2833146385 cites W2280278065 @default.
• W2833146385 cites W2337535033 @default.
• W2833146385 cites W2411552435 @default.
• W2833146385 cites W2655359989 @default.
• W2833146385 cites W2752448460 @default.
• W2833146385 cites W2759201606 @default.
• W2833146385 cites W2779484206 @default.
• W2833146385 cites W2790385118 @default.
• W2833146385 cites W2794347700 @default.
• W2833146385 cites W758578431 @default.
• W2833146385 doi "https://doi.org/10.1016/j.bone.2018.07.003" @default.
• W2833146385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29990585" @default.
• W2833146385 hasPublicationYear "2018" @default.
• W2833146385 type Work @default.
• W2833146385 sameAs 2833146385 @default.
• W2833146385 citedByCount "32" @default.
• W2833146385 countsByYear W28331463852018 @default.
• W2833146385 countsByYear W28331463852019 @default.
• W2833146385 countsByYear W28331463852020 @default.
• W2833146385 countsByYear W28331463852021 @default.
• W2833146385 countsByYear W28331463852022 @default.
• W2833146385 countsByYear W28331463852023 @default.
• W2833146385 crossrefType "journal-article" @default.
• W2833146385 hasAuthorship W2833146385A5004770379 @default.
• W2833146385 hasAuthorship W2833146385A5034217467 @default.
• W2833146385 hasAuthorship W2833146385A5042383355 @default.
• W2833146385 hasAuthorship W2833146385A5060302747 @default.
• W2833146385 hasAuthorship W2833146385A5080542506 @default.
• W2833146385 hasConcept C126322002 @default.
• W2833146385 hasConcept C134018914 @default.
• W2833146385 hasConcept C170493617 @default.
• W2833146385 hasConcept C2776033226 @default.
• W2833146385 hasConcept C2776541429 @default.

• next