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• W2836729867 abstract "Awareness of the basic pathogenetic mechanisms of thrombocytopenia occurence is a prerequisite to adequate treatment of complex cardiac patients. Introducing percutaneous coronary interventions along with both standard and novel antithrombotic drugs has significantly improved an acute coronary syndrome patients' prognosis, though it has also additionaly increased the risk for developing new types of thrombocytopenia, etiologically completely divergent but with the common denominator of substantially affecting new complication development and a rise in mortality. The most common thrombocytopenias occuring in consequence of percutaneous coronary interventions are induced mostly by heparin, GP IIb/IIIa inhibitors and iodinated contrast. Besides a well-known fact that a number of thrombocytopenias potentially lead to haemorrhagic syndrome, physicians must be fully conscious that there is a group of diseases manifested by thrombocytopenia also representing a primarily thrombotic risk factor, with the specific clinical significance being attached to antiphospholipid syndrome, heparin-induced thrombocytopenia type II as well as thrombotic thrombocytopenic purpura. Due to the possiblity of fast development of complications, a physician is obliged to detect this disease in a timely manner using adequate laboratory monitoring, define its cause and take appropriate measures, with particular stress placed on therapeutic treatment individualisation considering the great clinical complexity of these patients." @default.
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• W2836729867 date "2012-01-01" @default.
• W2836729867 modified "2023-10-17" @default.
• W2836729867 title "Adequate evaluation of thrombocytopenias as a prerequisite to effective cardiac patient treatment" @default.
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• W2836729867 doi "https://doi.org/10.5937/siks1204275a" @default.
• W2836729867 hasPublicationYear "2012" @default.
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