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- W2839219975 abstract "Abstract Objective Applying the morphological descriptors described in the MRI breast imaging and reporting data system (BIRADS) in characterizing enhancing breast lesions seen on CESM. Methods 178 breast lesions in patients with mean age 46 years in a prospective study were included. Morphological categorization of the included lesions was presented into focus, mass and non-mass forms. Furthermore classifications included (1) the margin, enhancement intensity for “focus” (2), the shape, margin and internal enhancement for “mass” and (3) the distribution and internal enhancement for “non-mass”. Each morphology descriptor was evaluated separately (irrespective of the other descriptors) by calculating its sensitivity, specificity, (PPV) and (NPV). Results This study included 104 malignant lesions versus 74 benign. Diagnostic accuracy parameters for CESM were sensitivity 98% (102/104) and specificity 76% (56/74). Irregular margin intense enhancement focus (1/8) was diagnosed malignant, (7/8) while regular margin faint enhancing foci were benign. Irregular shape, spiculated margin and heterogeneous internal enhancement descriptors of mass lesion descriptors conformed to malignancy (PPV 92.5% of the former and 88.7% of the latter, p value ≤ 0.001). Asymmetry with segmental distribution, (17/27) (70.8%) heterogeneous and clumped internal enhancement patterns were indicative for malignancy in non mass enhancement (PPV Conclusion MRI lexicon morphology descriptors can be applied (yet with few exceptions) in the characterization of enhancing breast lesions on CESM. The most sensitive descriptors for malignant lesions regarding masses are irregular, margins yet for NME the focal, ductal and segmental distribution with heterogeneous or clumped enhancing patterns. Still foci are controversial." @default.
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- W2839219975 date "2018-09-01" @default.
- W2839219975 modified "2023-10-03" @default.
- W2839219975 title "Interpretation of patterns of enhancement on contrast-enhanced spectral mammography: An approach to a standardized scheme" @default.
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- W2839219975 doi "https://doi.org/10.1016/j.ejrnm.2018.03.004" @default.
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