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- W2839431337 abstract "We synthesized polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en analogues on the polyglutamic acid back bone, via a spacer of alkyl ether at the C-7 position. These multivalent conjugates 9 and 10 showed enhancement of antiviral activity against infuenza A virus and more potent efficacy in vivo relative to a monomeric sialidase inhibitor." @default.
- W2839431337 created "2018-07-19" @default.
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- W2839431337 date "2002-08-01" @default.
- W2839431337 modified "2023-10-03" @default.
- W2839431337 title "Synthesis and anti-Influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives" @default.
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- W2839431337 doi "https://doi.org/10.1016/s0960-894x(02)00330-x" @default.
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