FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2842497194> ?p ?o ?g. }

• W2842497194 abstract "Polyparasitism is the rule in all animal species, including humans, and has an important role in pathogenicity, diagnosis and control measures. Among them, co-infections by gastrointestinal helminths and protists are very prevalent under natural conditions but experimental infections are relatively scarce. Thus, despite the frequent association of visceral Leishmania infections and intestinal helminth parasitism the experimental co-infection has not been addressed. Heligmosomoides polygyrus, an intestinal nematode of mice, is related to other helminths causing important pathologies and is a model species for immunological studies. Mice are valuable experimental model for visceral leishmaniasis.BALB/c mice infected with H. polygyrus (200 third-stage larvae, L3) were subsequently infected seven days later with Leishmania infantum (107 promastigotes) with the aim of determining the effect of the overinfection on the host response to the primary infection with the helminth.Overinfection with the protist did not affect the establishment rate of the nematode but induced a higher fecal egg output. Helminth burdens in co-infected animals were significant at the end of the experiment. Early unspecific immune suppression induced by the nematode in mesenteric lymph nodes was not switched by L. infantum infection. Co-infection elicited a higher serum antibody (IgG1) response against the helminth.Visceral leishmanial overinfection aggravated the early host response against primary infections with the intestinal helminth. This effect was evidenced by an increased longevity and higher production of non-protective antibodies." @default.
• W2842497194 created "2018-07-19" @default.
• W2842497194 creator A5024799006 @default.
• W2842497194 creator A5048044197 @default.
• W2842497194 creator A5050250236 @default.
• W2842497194 date "2018-07-11" @default.
• W2842497194 modified "2023-10-02" @default.
• W2842497194 title "Superimposed visceral leishmanial infection aggravates response to Heligmosomoides polygyrus" @default.
• W2842497194 cites W1493244949 @default.
• W2842497194 cites W1523736353 @default.
• W2842497194 cites W1790529736 @default.
• W2842497194 cites W1970868994 @default.
• W2842497194 cites W1976514444 @default.
• W2842497194 cites W2010185390 @default.
• W2842497194 cites W2011671647 @default.
• W2842497194 cites W2018267078 @default.
• W2842497194 cites W2032452120 @default.
• W2842497194 cites W2047299907 @default.
• W2842497194 cites W2075704438 @default.
• W2842497194 cites W2084424946 @default.
• W2842497194 cites W2089392576 @default.
• W2842497194 cites W2091000189 @default.
• W2842497194 cites W2110178493 @default.
• W2842497194 cites W2116779385 @default.
• W2842497194 cites W2123097142 @default.
• W2842497194 cites W2125078295 @default.
• W2842497194 cites W2128635872 @default.
• W2842497194 cites W2145946881 @default.
• W2842497194 cites W2146024433 @default.
• W2842497194 cites W2170075617 @default.
• W2842497194 cites W2170323587 @default.
• W2842497194 cites W2294083761 @default.
• W2842497194 cites W2341055768 @default.
• W2842497194 cites W2737331505 @default.
• W2842497194 cites W2738153183 @default.
• W2842497194 cites W4239591814 @default.
• W2842497194 cites W4255943186 @default.
• W2842497194 cites W4293247451 @default.
• W2842497194 cites W796590349 @default.
• W2842497194 cites W83647411 @default.
• W2842497194 doi "https://doi.org/10.1186/s13071-018-2987-1" @default.
• W2842497194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6042253" @default.
• W2842497194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29996937" @default.
• W2842497194 hasPublicationYear "2018" @default.
• W2842497194 type Work @default.
• W2842497194 sameAs 2842497194 @default.
• W2842497194 citedByCount "1" @default.
• W2842497194 countsByYear W28424971942019 @default.
• W2842497194 crossrefType "journal-article" @default.
• W2842497194 hasAuthorship W2842497194A5024799006 @default.
• W2842497194 hasAuthorship W2842497194A5048044197 @default.
• W2842497194 hasAuthorship W2842497194A5050250236 @default.
• W2842497194 hasBestOaLocation W28424971941 @default.
• W2842497194 hasConcept C165901193 @default.
• W2842497194 hasConcept C18903297 @default.
• W2842497194 hasConcept C203014093 @default.
• W2842497194 hasConcept C2775952312 @default.
• W2842497194 hasConcept C2776555147 @default.
• W2842497194 hasConcept C2778689377 @default.
• W2842497194 hasConcept C2778830712 @default.
• W2842497194 hasConcept C2778885919 @default.
• W2842497194 hasConcept C2779237934 @default.
• W2842497194 hasConcept C2781257258 @default.
• W2842497194 hasConcept C2781269127 @default.
• W2842497194 hasConcept C86803240 @default.
• W2842497194 hasConcept C8891405 @default.
• W2842497194 hasConceptScore W2842497194C165901193 @default.
• W2842497194 hasConceptScore W2842497194C18903297 @default.
• W2842497194 hasConceptScore W2842497194C203014093 @default.
• W2842497194 hasConceptScore W2842497194C2775952312 @default.
• W2842497194 hasConceptScore W2842497194C2776555147 @default.
• W2842497194 hasConceptScore W2842497194C2778689377 @default.
• W2842497194 hasConceptScore W2842497194C2778830712 @default.
• W2842497194 hasConceptScore W2842497194C2778885919 @default.
• W2842497194 hasConceptScore W2842497194C2779237934 @default.
• W2842497194 hasConceptScore W2842497194C2781257258 @default.
• W2842497194 hasConceptScore W2842497194C2781269127 @default.
• W2842497194 hasConceptScore W2842497194C86803240 @default.
• W2842497194 hasConceptScore W2842497194C8891405 @default.
• W2842497194 hasFunder F4320324278 @default.
• W2842497194 hasLocation W28424971941 @default.
• W2842497194 hasLocation W28424971942 @default.
• W2842497194 hasLocation W28424971943 @default.
• W2842497194 hasLocation W28424971944 @default.
• W2842497194 hasLocation W28424971945 @default.
• W2842497194 hasOpenAccess W2842497194 @default.
• W2842497194 hasPrimaryLocation W28424971941 @default.
• W2842497194 hasRelatedWork W1995491273 @default.
• W2842497194 hasRelatedWork W1997610036 @default.
• W2842497194 hasRelatedWork W2014672666 @default.
• W2842497194 hasRelatedWork W2046002234 @default.
• W2842497194 hasRelatedWork W2063931411 @default.
• W2842497194 hasRelatedWork W2146476791 @default.
• W2842497194 hasRelatedWork W216133395 @default.
• W2842497194 hasRelatedWork W2289229009 @default.
• W2842497194 hasRelatedWork W2842497194 @default.
• W2842497194 hasRelatedWork W4282970315 @default.
• W2842497194 isParatext "false" @default.
• W2842497194 isRetracted "false" @default.
• W2842497194 magId "2842497194" @default.

• next