Matches in SemOpenAlex for { <https://semopenalex.org/work/W28496630> ?p ?o ?g. }
- W28496630 endingPage "176" @default.
- W28496630 startingPage "169" @default.
- W28496630 abstract "This chapter discusses developmental immunology, with an emphasis on the pulmonary system in the primates. It is well established that newborn infants have a limited ability to mount an effective immune response against microbes. As there are limited numbers of precursor or 'memory' lymphocytes within neonatal airways, it is likely that the infant is most dependent upon immune cell expansion in regional lymph nodes to respond to environmental exposure to antigens and infectious agents. The predominance of macrophages within airways of infants is likely to be representative of the first level of innate immunity established for the 'naive' lung. As the infant matures and comes in contact with environmental antigens, cells from the adaptive arm of the immune system contribute to the resident leukocyte population of the airways. Dendritic cells are the primary antigen-presenting cells of the lung and are critical for the immunosurveillance of inhaled antigens. By the 13th week of gestation, HLA-DR positive dendritic-like cells are observed in the human fetal lung. HLA-DR positive cells within the fetal lung are dispersed as single cells within the interstitium, do not stain for markers of macrophage/monocyte lineage, and increase in frequency with gestational age." @default.
- W28496630 created "2016-06-24" @default.
- W28496630 creator A5047788381 @default.
- W28496630 date "2004-01-01" @default.
- W28496630 modified "2023-10-17" @default.
- W28496630 title "Development of the Pulmonary Immune System" @default.
- W28496630 cites W1623596840 @default.
- W28496630 cites W1782315813 @default.
- W28496630 cites W1831285580 @default.
- W28496630 cites W1932276950 @default.
- W28496630 cites W1938172771 @default.
- W28496630 cites W1944543056 @default.
- W28496630 cites W1969200707 @default.
- W28496630 cites W1973299451 @default.
- W28496630 cites W1978532917 @default.
- W28496630 cites W1980119094 @default.
- W28496630 cites W1985783364 @default.
- W28496630 cites W1992100179 @default.
- W28496630 cites W1992126368 @default.
- W28496630 cites W1994616457 @default.
- W28496630 cites W2000125568 @default.
- W28496630 cites W2000602561 @default.
- W28496630 cites W2002315852 @default.
- W28496630 cites W2002604831 @default.
- W28496630 cites W2003007371 @default.
- W28496630 cites W2008955150 @default.
- W28496630 cites W2009531085 @default.
- W28496630 cites W2010662462 @default.
- W28496630 cites W2012749291 @default.
- W28496630 cites W2016839495 @default.
- W28496630 cites W2023855895 @default.
- W28496630 cites W2027442689 @default.
- W28496630 cites W2028362346 @default.
- W28496630 cites W2030885533 @default.
- W28496630 cites W2032441389 @default.
- W28496630 cites W2034389382 @default.
- W28496630 cites W2042574089 @default.
- W28496630 cites W2044851958 @default.
- W28496630 cites W2045509432 @default.
- W28496630 cites W2051459955 @default.
- W28496630 cites W2060767159 @default.
- W28496630 cites W2061134060 @default.
- W28496630 cites W2063240654 @default.
- W28496630 cites W2063399038 @default.
- W28496630 cites W2064716896 @default.
- W28496630 cites W2067842553 @default.
- W28496630 cites W2071458543 @default.
- W28496630 cites W2071561098 @default.
- W28496630 cites W2080232429 @default.
- W28496630 cites W2080664825 @default.
- W28496630 cites W2081671448 @default.
- W28496630 cites W2088421297 @default.
- W28496630 cites W2092217561 @default.
- W28496630 cites W2099353457 @default.
- W28496630 cites W2100582080 @default.
- W28496630 cites W2114055381 @default.
- W28496630 cites W2119079510 @default.
- W28496630 cites W2119884413 @default.
- W28496630 cites W2123151875 @default.
- W28496630 cites W2127563396 @default.
- W28496630 cites W2128068274 @default.
- W28496630 cites W2131199999 @default.
- W28496630 cites W2132149007 @default.
- W28496630 cites W2132351750 @default.
- W28496630 cites W2133188511 @default.
- W28496630 cites W2139659954 @default.
- W28496630 cites W2169309117 @default.
- W28496630 cites W2188088995 @default.
- W28496630 cites W2188705799 @default.
- W28496630 cites W2276328619 @default.
- W28496630 cites W4211185484 @default.
- W28496630 cites W4233728890 @default.
- W28496630 cites W4319054095 @default.
- W28496630 cites W4376453204 @default.
- W28496630 doi "https://doi.org/10.1016/b978-012324751-3/50045-0" @default.
- W28496630 hasPublicationYear "2004" @default.
- W28496630 type Work @default.
- W28496630 sameAs 28496630 @default.
- W28496630 citedByCount "4" @default.
- W28496630 countsByYear W284966302017 @default.
- W28496630 countsByYear W284966302020 @default.
- W28496630 countsByYear W284966302022 @default.
- W28496630 crossrefType "book-chapter" @default.
- W28496630 hasAuthorship W28496630A5047788381 @default.
- W28496630 hasConcept C126322002 @default.
- W28496630 hasConcept C147483822 @default.
- W28496630 hasConcept C172680121 @default.
- W28496630 hasConcept C193419808 @default.
- W28496630 hasConcept C202751555 @default.
- W28496630 hasConcept C203014093 @default.
- W28496630 hasConcept C2776090121 @default.
- W28496630 hasConcept C2776885095 @default.
- W28496630 hasConcept C2777714996 @default.
- W28496630 hasConcept C2779234561 @default.
- W28496630 hasConcept C2779244956 @default.
- W28496630 hasConcept C2908647359 @default.
- W28496630 hasConcept C54355233 @default.
- W28496630 hasConcept C55493867 @default.