FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2852235747> ?p ?o ?g. }

• W2852235747 abstract "Hemodynamic instability is one of the leading causes of intensive care unit (ICU) admission. Early stabilization of hemodynamics is associated with improved outcome. The monitoring used to guide hemodynamic support may influence the time needed to achieve stable hemodynamics. Visualization of the heart using echocardiography offers the advantage of direct measurement of cardiac volumes and ventricular function. A miniaturized monoplane transesophageal echocardiography (TEE) probe was developed, allowing for almost continuous qualitative hemodynamic TEE assessment (hTEE) after brief bedside training. The primary objective of the study is to assess whether hemodynamic monitoring using the hTEE technology shortens time to resolution of shock in ICU patients in comparison to standard monitoring using a central venous catheter, pulmonary artery catheter, or conventional echocardiography.Five hundred consecutive subjects with circulatory shock (low mean arterial blood pressure (MAP) and signs of organ hypoperfusion) at the time of ICU admission are included in the study. The subjects are randomly assigned to one of four groups using a 2 × 2 factorial design stratified by method of hemodynamic monitoring (hTEE vs standard hemodynamic monitoring) and frequency of hemodynamic assessments (minimum every 4 h vs standard of care). The primary study outcome is the time from study inclusion to resolution of circulatory shock, defined as MAP > 60 mmHg for ≥ 4 h after discontinuation of vasopressors and inotropes. The hTEE monitoring consists of the acquisition of three defined echocardiography views: Transgastric mid-esophageal short axis with measurement of fractional area change of left ventricle, mid-esophageal four-chamber view with measurement of the ratio of right to left ventricular area, and mid-esophageal ascending aortic short-axis view with measurement of the superior vena cava collapsibility index. In the control groups, monitoring modalities, including conventional TTE and TEE but not hTEE, are at the discretion of the treating physician. The interpretation of hemodynamic monitoring and the subsequent changes in patient management are recorded after each hemodynamic assessment. Differences in the primary and further secondary time-to-event outcomes will be assessed using a competing risk model accounting for the competing risk of death.The effect of using echocardiography as a monitoring modality on relevant patient outcomes has not been established so far. The study at hand may be one of the first trials to provide detailed data on effectiveness and safety of echocardiography to guide treatment in patients with circulatory shock.ClinicalTrials.gov, ID: NCT02048566. Registered on January 29, 2014." @default.
• W2852235747 created "2018-07-19" @default.
• W2852235747 creator A5008320722 @default.
• W2852235747 creator A5020552058 @default.
• W2852235747 creator A5024578688 @default.
• W2852235747 creator A5027655814 @default.
• W2852235747 creator A5039323300 @default.
• W2852235747 creator A5050049265 @default.
• W2852235747 creator A5057407885 @default.
• W2852235747 creator A5016684976 @default.
• W2852235747 date "2018-07-06" @default.
• W2852235747 modified "2023-09-22" @default.
• W2852235747 title "Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients – study protocol for a randomized controlled trial" @default.
• W2852235747 cites W1519553794 @default.
• W2852235747 cites W2003295005 @default.
• W2852235747 cites W2021667729 @default.
• W2852235747 cites W2024321464 @default.
• W2852235747 cites W2035488390 @default.
• W2852235747 cites W2038981426 @default.
• W2852235747 cites W2050128368 @default.
• W2852235747 cites W2053138665 @default.
• W2852235747 cites W2060077301 @default.
• W2852235747 cites W2067586272 @default.
• W2852235747 cites W2080824021 @default.
• W2852235747 cites W2095944485 @default.
• W2852235747 cites W2110132732 @default.
• W2852235747 cites W2113703451 @default.
• W2852235747 cites W2114932396 @default.
• W2852235747 cites W2119509742 @default.
• W2852235747 cites W2141352551 @default.
• W2852235747 cites W2143021559 @default.
• W2852235747 cites W2588544354 @default.
• W2852235747 cites W2773915045 @default.
• W2852235747 cites W4211104669 @default.
• W2852235747 cites W4233195373 @default.
• W2852235747 cites W4233301778 @default.
• W2852235747 cites W4292856638 @default.
• W2852235747 cites W7921539 @default.
• W2852235747 doi "https://doi.org/10.1186/s13063-018-2714-4" @default.
• W2852235747 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6205795" @default.
• W2852235747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30373639" @default.
• W2852235747 hasPublicationYear "2018" @default.
• W2852235747 type Work @default.
• W2852235747 sameAs 2852235747 @default.
• W2852235747 citedByCount "8" @default.
• W2852235747 countsByYear W28522357472018 @default.
• W2852235747 countsByYear W28522357472019 @default.
• W2852235747 countsByYear W28522357472020 @default.
• W2852235747 countsByYear W28522357472021 @default.
• W2852235747 crossrefType "journal-article" @default.
• W2852235747 hasAuthorship W2852235747A5008320722 @default.
• W2852235747 hasAuthorship W2852235747A5016684976 @default.
• W2852235747 hasAuthorship W2852235747A5020552058 @default.
• W2852235747 hasAuthorship W2852235747A5024578688 @default.
• W2852235747 hasAuthorship W2852235747A5027655814 @default.
• W2852235747 hasAuthorship W2852235747A5039323300 @default.
• W2852235747 hasAuthorship W2852235747A5050049265 @default.
• W2852235747 hasAuthorship W2852235747A5057407885 @default.
• W2852235747 hasBestOaLocation W28522357471 @default.
• W2852235747 hasConcept C126322002 @default.
• W2852235747 hasConcept C139940330 @default.
• W2852235747 hasConcept C164705383 @default.
• W2852235747 hasConcept C177713679 @default.
• W2852235747 hasConcept C178853913 @default.
• W2852235747 hasConcept C2776376669 @default.
• W2852235747 hasConcept C2777953023 @default.
• W2852235747 hasConcept C2779892169 @default.
• W2852235747 hasConcept C2781300812 @default.
• W2852235747 hasConcept C2987404301 @default.
• W2852235747 hasConcept C35207712 @default.
• W2852235747 hasConcept C42219234 @default.
• W2852235747 hasConcept C71924100 @default.
• W2852235747 hasConcept C84393581 @default.
• W2852235747 hasConceptScore W2852235747C126322002 @default.
• W2852235747 hasConceptScore W2852235747C139940330 @default.
• W2852235747 hasConceptScore W2852235747C164705383 @default.
• W2852235747 hasConceptScore W2852235747C177713679 @default.
• W2852235747 hasConceptScore W2852235747C178853913 @default.
• W2852235747 hasConceptScore W2852235747C2776376669 @default.
• W2852235747 hasConceptScore W2852235747C2777953023 @default.
• W2852235747 hasConceptScore W2852235747C2779892169 @default.
• W2852235747 hasConceptScore W2852235747C2781300812 @default.
• W2852235747 hasConceptScore W2852235747C2987404301 @default.
• W2852235747 hasConceptScore W2852235747C35207712 @default.
• W2852235747 hasConceptScore W2852235747C42219234 @default.
• W2852235747 hasConceptScore W2852235747C71924100 @default.
• W2852235747 hasConceptScore W2852235747C84393581 @default.
• W2852235747 hasIssue "1" @default.
• W2852235747 hasLocation W28522357471 @default.
• W2852235747 hasLocation W28522357472 @default.
• W2852235747 hasLocation W28522357473 @default.
• W2852235747 hasLocation W28522357474 @default.
• W2852235747 hasLocation W28522357475 @default.
• W2852235747 hasOpenAccess W2852235747 @default.
• W2852235747 hasPrimaryLocation W28522357471 @default.
• W2852235747 hasRelatedWork W1824412291 @default.
• W2852235747 hasRelatedWork W2042590798 @default.
• W2852235747 hasRelatedWork W2081273260 @default.
• W2852235747 hasRelatedWork W2283135271 @default.
• W2852235747 hasRelatedWork W2330578132 @default.

• next