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• W2854051729 abstract "Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA), is a life saving intervention employed during heavy internal bleeding in the pelvis and abdomen. A balloon is inserted into the aorta to prevent distal blood flow. Aim: To develop a system using soft-technologies that permits adaptive interactions in an unpredictable biological environment. A system that acts as a diameter sensor and flow modulation device for catheter based application that can safely interact with humans. Methods: We hypothesized that the internal pressure of the balloon would rise as it presses against the aortic lumen, thus providing a surrogate marker for diameter. The device constructed measures balloon pressure via a tee junction at the syringe catheter interface. Repeat measurements (ten) for tubes of diameters, 10, 8, 7, 6 and 5 mm were obtained giving 50 sets of data. A neural network was created and trained. Unseen data was used to test the network. Blood flow modulation was achieved via a tendon deformable balloon. Deformability was achieved by gluing strings on the internal surface of the balloon. Results: The diameter sensor showed that pressure peaks were higher in smaller tubes with 7 mm showing a peak at 10.9 PSI, 8 mm showing a peak at 9.7 PSI and 10 mm showing a peak at 8 PSI. The peaks also occurred earlier at 8200, 8600, 8800 ms for 7, 8 and 10 mm respectively. The 5 and 6 mm diameter tubes had higher pressures when compared to the rest of the data for their respective times. The trained neural network made very accurate predictions of the diameter using the test sets with a RMSE of 0.022 (0.22 mm). Flow modulation was achieved using strings that pinched the balloon inwards allowing flow of fluid at that point, distal migration of the balloon was avoided. Conclusion: A portable soft robotic system that accurately measures diameter and allows blood flow modulation was successfully built. The system is simple enough to be incorporated into current catheters with little modification. The first steps towards the development of a bespoke system for haemorrhage control has been demonstrated. Future work will focus on integrating the system with a control loop and testing the system in vivo." @default.
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• W2854051729 date "2018-04-01" @default.
• W2854051729 modified "2023-09-25" @default.
• W2854051729 title "Development of an adaptable, soft robot with an aortic diameter sensor to modulate blood flow in an extreme biological environment" @default.
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• W2854051729 doi "https://doi.org/10.1109/robosoft.2018.8404943" @default.
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