FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2854342237> ?p ?o ?g. }

• W2854342237 endingPage "e11517" @default.
• W2854342237 startingPage "e11517" @default.
• W2854342237 abstract "Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS). However, alterations of Lp-PLA2 levels during ACS and its association with cardiovascular outcome are unclear. Our aim was to investigate the change in Lp-PLA2 and its association with cardiovascular outcome in patients with ACS. A total of 79 patients with ACS came from the coronary care unit (CCU) between June 1, 2015 and August 31, 2016 in this longitudinal study. Serum levels of Lp-PLA2, troponin I, and creatine kinase isoenzymes MB (CK-MB) were measured at admission, on the first morning (D1), on the second morning of hospitalization (D2), and on the last second morning before discharge (D4). The patients were followed up till November 30, 2016. The primary outcomes were cardiovascular death and cardiovascular rehospitalization. Kaplan–Meier analysis and Cox proportional hazard models were used to identify risk factors for poor outcome in patients with ACS. All patients were followed up for 10.6 ± 4.7 months. The patients were divided into 2 groups according to the median of Lp-PLA2: lower Lp-PLA2 group and higher Lp-PLA2 group. Elevated levels of Lp-PLA2 significantly decreased during the early phases of ACS in higher Lp-PLA2 group. And Lp-PLA2 level increased at first and then decreased in lower Lp-PLA2 group. Kaplan–Meier analysis showed that patients with elevated Lp-PLA2 had a lower cardiovascular event-free survival (log-rank χ2 = 4.736, P = .030) than those with lower Lp-PLA2. Cox regression analysis indicated that high Lp-PLA2 level (hazard ratio [HR] = 1.005, 95% confidence interval [CI] = 1.002–1.008, P = .003), time delay from symptom onset to admission (HR = 1.088, 95% CI = 1.038–1.139, P < .001) independently predicted cardiovascular event in patients with ACS after adjusting for potential confounders. Serum level of Lp-PLA2 altered considerably during the early phase of ACS and increased Lp-PLA2 independently predicted cardiovascular outcome in patients with ACS after adjustment for potential confounders." @default.
• W2854342237 created "2018-07-19" @default.
• W2854342237 creator A5020589827 @default.
• W2854342237 creator A5030739481 @default.
• W2854342237 creator A5033020983 @default.
• W2854342237 creator A5046866473 @default.
• W2854342237 creator A5061838242 @default.
• W2854342237 date "2018-07-01" @default.
• W2854342237 modified "2023-10-16" @default.
• W2854342237 title "Change in lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndrome" @default.
• W2854342237 cites W1496215958 @default.
• W2854342237 cites W1572528121 @default.
• W2854342237 cites W1966487341 @default.
• W2854342237 cites W1975010240 @default.
• W2854342237 cites W1980428094 @default.
• W2854342237 cites W1986337010 @default.
• W2854342237 cites W2026770496 @default.
• W2854342237 cites W2028684029 @default.
• W2854342237 cites W2039087987 @default.
• W2854342237 cites W2060845576 @default.
• W2854342237 cites W2066963386 @default.
• W2854342237 cites W2093522781 @default.
• W2854342237 cites W2109308300 @default.
• W2854342237 cites W2113187337 @default.
• W2854342237 cites W2116882603 @default.
• W2854342237 cites W2125538998 @default.
• W2854342237 cites W2135171686 @default.
• W2854342237 cites W2152068506 @default.
• W2854342237 cites W2157526825 @default.
• W2854342237 cites W2170274940 @default.
• W2854342237 cites W2173971756 @default.
• W2854342237 cites W2317790557 @default.
• W2854342237 cites W2464586391 @default.
• W2854342237 cites W2552065196 @default.
• W2854342237 cites W2577541106 @default.
• W2854342237 cites W2591466012 @default.
• W2854342237 cites W2600082108 @default.
• W2854342237 cites W2767280379 @default.
• W2854342237 doi "https://doi.org/10.1097/md.0000000000011517" @default.
• W2854342237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6076090" @default.
• W2854342237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29995820" @default.
• W2854342237 hasPublicationYear "2018" @default.
• W2854342237 type Work @default.
• W2854342237 sameAs 2854342237 @default.
• W2854342237 citedByCount "14" @default.
• W2854342237 countsByYear W28543422372018 @default.
• W2854342237 countsByYear W28543422372019 @default.
• W2854342237 countsByYear W28543422372020 @default.
• W2854342237 countsByYear W28543422372021 @default.
• W2854342237 countsByYear W28543422372022 @default.
• W2854342237 countsByYear W28543422372023 @default.
• W2854342237 crossrefType "journal-article" @default.
• W2854342237 hasAuthorship W2854342237A5020589827 @default.
• W2854342237 hasAuthorship W2854342237A5030739481 @default.
• W2854342237 hasAuthorship W2854342237A5033020983 @default.
• W2854342237 hasAuthorship W2854342237A5046866473 @default.
• W2854342237 hasAuthorship W2854342237A5061838242 @default.
• W2854342237 hasBestOaLocation W28543422371 @default.
• W2854342237 hasConcept C126322002 @default.
• W2854342237 hasConcept C164705383 @default.
• W2854342237 hasConcept C207103383 @default.
• W2854342237 hasConcept C2776104379 @default.
• W2854342237 hasConcept C2777034527 @default.
• W2854342237 hasConcept C2777698277 @default.
• W2854342237 hasConcept C2778163477 @default.
• W2854342237 hasConcept C2779519902 @default.
• W2854342237 hasConcept C2780072125 @default.
• W2854342237 hasConcept C44249647 @default.
• W2854342237 hasConcept C500558357 @default.
• W2854342237 hasConcept C50382708 @default.
• W2854342237 hasConcept C71924100 @default.
• W2854342237 hasConceptScore W2854342237C126322002 @default.
• W2854342237 hasConceptScore W2854342237C164705383 @default.
• W2854342237 hasConceptScore W2854342237C207103383 @default.
• W2854342237 hasConceptScore W2854342237C2776104379 @default.
• W2854342237 hasConceptScore W2854342237C2777034527 @default.
• W2854342237 hasConceptScore W2854342237C2777698277 @default.
• W2854342237 hasConceptScore W2854342237C2778163477 @default.
• W2854342237 hasConceptScore W2854342237C2779519902 @default.
• W2854342237 hasConceptScore W2854342237C2780072125 @default.
• W2854342237 hasConceptScore W2854342237C44249647 @default.
• W2854342237 hasConceptScore W2854342237C500558357 @default.
• W2854342237 hasConceptScore W2854342237C50382708 @default.
• W2854342237 hasConceptScore W2854342237C71924100 @default.
• W2854342237 hasIssue "28" @default.
• W2854342237 hasLocation W28543422371 @default.
• W2854342237 hasLocation W28543422372 @default.
• W2854342237 hasLocation W28543422373 @default.
• W2854342237 hasOpenAccess W2854342237 @default.
• W2854342237 hasPrimaryLocation W28543422371 @default.
• W2854342237 hasRelatedWork W1551526463 @default.
• W2854342237 hasRelatedWork W1965746743 @default.
• W2854342237 hasRelatedWork W1978747192 @default.
• W2854342237 hasRelatedWork W1987726377 @default.
• W2854342237 hasRelatedWork W2035598300 @default.
• W2854342237 hasRelatedWork W2066343714 @default.
• W2854342237 hasRelatedWork W2170549593 @default.
• W2854342237 hasRelatedWork W2184636034 @default.

• next