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- W2854405561 endingPage "1170" @default.
- W2854405561 startingPage "1157" @default.
- W2854405561 abstract "Concerns about climate change have driven research on the production of lipid-derived biofuels as an alternative and renewable liquid fuel source. Using oleaginous yeasts for lipid synthesis creates the potential for cost-effective industrial-scale operations due to their ability to reach high lipid titer, yield, and productivity resulting from their unique metabolism. Yarrowia lipolytica is the model oleaginous yeast, with the best-studied lipid metabolism, the greatest number of genetic tools, and a fully sequenced genome. In this review we highlight multiomics studies that elucidate the mechanisms allowing this yeast to achieve lipid overaccumulation and then present several major metabolic engineering efforts that enhanced the production metrics in Y. lipolytica. Recent achievements that applied novel engineering strategies are emphasized." @default.
- W2854405561 created "2018-07-19" @default.
- W2854405561 creator A5009763658 @default.
- W2854405561 creator A5036881486 @default.
- W2854405561 creator A5037633982 @default.
- W2854405561 date "2018-11-01" @default.
- W2854405561 modified "2023-10-13" @default.
- W2854405561 title "Holistic Approaches in Lipid Production by Yarrowia lipolytica" @default.
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- W2854405561 doi "https://doi.org/10.1016/j.tibtech.2018.06.007" @default.
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- W2854405561 hasPublicationYear "2018" @default.
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