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- W285571808 abstract "In functional imaging with SPECT, differential uptake measurements within the tomographic plane are important. In many investigations, a distributed source or multiple sources within this plane are imaged. Backprojected noise may be significant, influencing differential uptake. Noise factors, apart from backprojection algorithms include photon scattering and collimator photon penetration. The influence of noise on differential uptake within the transverse plane was empirically evaluated for Tc-99m (140 keV), Ga-67, 993,184 keV) and I-131 (364 keV). A Picker International SPECT system, equipped with LEC and thick septa MEC and Iodine collimators (theoretical leakage for both 20 x 10/sup 6/) to minimize statistical (unstructed) noise. For given acquisition and filter parameters, the noise level for Ga-67 was approximately three times greater than the Tc-99m, the latter attributed to scatter contribution to the lower energy window. This noise was non-uniform and degraded differential uptake measurements. The noise level for I-131 was approximately twice that for Tc-99m and was more uniformmore » than Ga-67. The noise was attributed, in part, to photon penetration. Despite difference in collimation, data suggest that provided collimator sensitivity can be reduced, the limiting noise factor is photon scattering where multiple peaks are involved.« less" @default.
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- W285571808 date "1984-01-01" @default.
- W285571808 modified "2023-09-27" @default.
- W285571808 title "SPECT imaging (140-364 keV): Influence of photon scattering and penetration on backprojected noise within tomographic plane" @default.
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