FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2857156700> ?p ?o ?g. }

• W2857156700 abstract "Mercury is a very harmful heavy metal and it has been shown to affect the nervous system mainly, and has contributed a lot to neurodegenerative diseases and disorders. Through time, there has been an increase in the search for more knowledge on how to address the treatment of the diseases associated with Mercury Chloride exposure. Researchers have shown some protective effect of some medicinal plants, which is why this study is done to investigate Salacia reticulata for protective effects against nervous disorders. The study was aimed at evaluating the antidegenerative effects of Salacia reticulata on mercury chloride exposure on the cellular architecture and spatial learning and memory of adult male mice. Twenty-five male mice with an average weight of (14.5-26 g) were divided into five groups of five mice per group and treated as follows. Group A; control group=2 mls of Placebo, Group B (HgCl2 at 7 mg/kgbw). Group C (HgCl2 at (7 mg/kgbw with Salacia reticulata at (200 mg/kgbw), Group D (HgCl at 7 mg/kgbw) with Salacia reticulata at (250 mg/kgbw). Group E (HgCl2; 7 mg/kgbw, with 0.2 ml pu of Vitamin E. HgCl2 was administered at a single dose orally while S. reticulate was administered orally daily for 14 days. The results from the Y-maze test showed an increase in the meantime taken by the animals to make alternations in the mercury treated group compared to the normal control group and Salacia reticulata treated groups, this is suggestive of neurological toxicity of mercury chloride to learning and memory loss. Histological results showed degeneration of the pyramidal cells of the hippocampus in mercury chloride treated group, while preservation of cellular profile and neuronal cells was seen in the Salacia reticulata treated group C and D as compared to group B (HgCl2 group only) and Vitamin E treated groups. Therefore, S. reticulata ameliorated memory loss in the hippocampus caused by mercury toxicity in adult male mice and is neuroprotective as seen in the microarchitecture of Pyramidal cells, fibers and neuropil evidenced in the hippocampus of mice treated." @default.
• W2857156700 created "2018-07-19" @default.
• W2857156700 creator A5000744872 @default.
• W2857156700 creator A5006746444 @default.
• W2857156700 creator A5035700962 @default.
• W2857156700 creator A5048982730 @default.
• W2857156700 date "2018-01-01" @default.
• W2857156700 modified "2023-09-26" @default.
• W2857156700 title "Antidegenerative and Neurobehavioral Effects of Ethanolic Root Extract of Salacia reticulata on Mercury Chloride Induced Cellular Damage in the Hippocampus of Adult Male Mice" @default.
• W2857156700 cites W1966521314 @default.
• W2857156700 cites W1996586383 @default.
• W2857156700 cites W2012550963 @default.
• W2857156700 cites W2013836023 @default.
• W2857156700 cites W2032230256 @default.
• W2857156700 cites W2039920104 @default.
• W2857156700 cites W2064569222 @default.
• W2857156700 cites W2091041795 @default.
• W2857156700 cites W2140665078 @default.
• W2857156700 cites W2141992086 @default.
• W2857156700 cites W2149776295 @default.
• W2857156700 cites W2163589838 @default.
• W2857156700 cites W2168367599 @default.
• W2857156700 cites W2805608169 @default.
• W2857156700 doi "https://doi.org/10.4172/2157-7099.1000508" @default.
• W2857156700 hasPublicationYear "2018" @default.
• W2857156700 type Work @default.
• W2857156700 sameAs 2857156700 @default.
• W2857156700 citedByCount "1" @default.
• W2857156700 countsByYear W28571567002020 @default.
• W2857156700 crossrefType "journal-article" @default.
• W2857156700 hasAuthorship W2857156700A5000744872 @default.
• W2857156700 hasAuthorship W2857156700A5006746444 @default.
• W2857156700 hasAuthorship W2857156700A5035700962 @default.
• W2857156700 hasAuthorship W2857156700A5048982730 @default.
• W2857156700 hasBestOaLocation W28571567001 @default.
• W2857156700 hasConcept C134018914 @default.
• W2857156700 hasConcept C169760540 @default.
• W2857156700 hasConcept C199360897 @default.
• W2857156700 hasConcept C2777777548 @default.
• W2857156700 hasConcept C2781161787 @default.
• W2857156700 hasConcept C2992926266 @default.
• W2857156700 hasConcept C33070731 @default.
• W2857156700 hasConcept C41008148 @default.
• W2857156700 hasConcept C556039675 @default.
• W2857156700 hasConcept C71924100 @default.
• W2857156700 hasConcept C86803240 @default.
• W2857156700 hasConceptScore W2857156700C134018914 @default.
• W2857156700 hasConceptScore W2857156700C169760540 @default.
• W2857156700 hasConceptScore W2857156700C199360897 @default.
• W2857156700 hasConceptScore W2857156700C2777777548 @default.
• W2857156700 hasConceptScore W2857156700C2781161787 @default.
• W2857156700 hasConceptScore W2857156700C2992926266 @default.
• W2857156700 hasConceptScore W2857156700C33070731 @default.
• W2857156700 hasConceptScore W2857156700C41008148 @default.
• W2857156700 hasConceptScore W2857156700C556039675 @default.
• W2857156700 hasConceptScore W2857156700C71924100 @default.
• W2857156700 hasConceptScore W2857156700C86803240 @default.
• W2857156700 hasIssue "03" @default.
• W2857156700 hasLocation W28571567001 @default.
• W2857156700 hasOpenAccess W2857156700 @default.
• W2857156700 hasPrimaryLocation W28571567001 @default.
• W2857156700 hasRelatedWork W15596799 @default.
• W2857156700 hasRelatedWork W2046968049 @default.
• W2857156700 hasRelatedWork W2092098622 @default.
• W2857156700 hasRelatedWork W2403081093 @default.
• W2857156700 hasRelatedWork W2766811916 @default.
• W2857156700 hasRelatedWork W2975173834 @default.
• W2857156700 hasRelatedWork W2985225563 @default.
• W2857156700 hasRelatedWork W3022483608 @default.
• W2857156700 hasRelatedWork W3036223255 @default.
• W2857156700 hasRelatedWork W3137120495 @default.
• W2857156700 hasVolume "09" @default.
• W2857156700 isParatext "false" @default.
• W2857156700 isRetracted "false" @default.
• W2857156700 magId "2857156700" @default.
• W2857156700 workType "article" @default.