FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2857891436> ?p ?o ?g. }

• W2857891436 endingPage "7247" @default.
• W2857891436 startingPage "7237" @default.
• W2857891436 abstract "Afferent input from the periphery to the cortex contributes to the control of grasping. How sensory input is gated along the ascending sensory pathway and its functional role during gross and fine grasping in humans remain largely unknown. To address this question, we assessed somatosensory-evoked potential components reflecting activation at subcortical and cortical levels and psychophysical tests at rest, during index finger abduction, precision, and power grip. We found that sensory gating at subcortical level and in the primary somatosensory cortex (S1), as well as intracortical inhibition in the S1, increased during power grip compared with the other tasks. To probe the functional relevance of gating in the S1, we examined somatosensory temporal discrimination threshold by measuring the shortest time interval to perceive a pair of electrical stimuli. Somatosensory temporal discrimination threshold increased during power grip, and higher threshold was associated with increased intracortical inhibition in the S1. These novel findings indicate that humans gate sensory input at subcortical level and in the S1 largely during gross compared with fine grasping. Inhibitory processes in the S1 may increase discrimination threshold to allow better performance during power grip.SIGNIFICANCE STATEMENT Most of our daily life actions involve grasping. Here, we demonstrate that gating of afferent input increases at subcortical level and in the primary somatosensory cortex (S1) during gross compared with fine grasping in intact humans. The precise timing of sensory information is critical for human perception and behavior. Notably, we found that the ability to perceive a pair of electrical stimuli, as measured by the somatosensory temporal discrimination threshold, increased during power grip compared with the other tasks. We propose that reduced afferent input to the S1 during gross grasping behaviors diminishes temporal discrimination of sensory processes related, at least in part, to increased inhibitory processes within the S1." @default.
• W2857891436 created "2018-07-19" @default.
• W2857891436 creator A5033942784 @default.
• W2857891436 creator A5053964666 @default.
• W2857891436 creator A5055056053 @default.
• W2857891436 date "2018-07-05" @default.
• W2857891436 modified "2023-10-13" @default.
• W2857891436 title "Gating of Sensory Input at Subcortical and Cortical Levels during Grasping in Humans" @default.
• W2857891436 cites W13011937 @default.
• W2857891436 cites W1837834442 @default.
• W2857891436 cites W1854011899 @default.
• W2857891436 cites W1854713433 @default.
• W2857891436 cites W1924066324 @default.
• W2857891436 cites W1969701888 @default.
• W2857891436 cites W1970817294 @default.
• W2857891436 cites W1976072557 @default.
• W2857891436 cites W1980412874 @default.
• W2857891436 cites W1983163812 @default.
• W2857891436 cites W1989150275 @default.
• W2857891436 cites W1990177704 @default.
• W2857891436 cites W1996934033 @default.
• W2857891436 cites W2003726161 @default.
• W2857891436 cites W2015577300 @default.
• W2857891436 cites W2019109017 @default.
• W2857891436 cites W2020264699 @default.
• W2857891436 cites W2024614767 @default.
• W2857891436 cites W2026920237 @default.
• W2857891436 cites W2027655712 @default.
• W2857891436 cites W2028244793 @default.
• W2857891436 cites W2028899450 @default.
• W2857891436 cites W2034267992 @default.
• W2857891436 cites W2037844204 @default.
• W2857891436 cites W2046034124 @default.
• W2857891436 cites W2049104523 @default.
• W2857891436 cites W2053972133 @default.
• W2857891436 cites W2054093267 @default.
• W2857891436 cites W2054549571 @default.
• W2857891436 cites W2054850359 @default.
• W2857891436 cites W2056418007 @default.
• W2857891436 cites W2058131086 @default.
• W2857891436 cites W2060894684 @default.
• W2857891436 cites W2062952821 @default.
• W2857891436 cites W2065807936 @default.
• W2857891436 cites W2069011998 @default.
• W2857891436 cites W2070726726 @default.
• W2857891436 cites W2074936002 @default.
• W2857891436 cites W2079608001 @default.
• W2857891436 cites W2080025475 @default.
• W2857891436 cites W2081435495 @default.
• W2857891436 cites W2081435868 @default.
• W2857891436 cites W2082652978 @default.
• W2857891436 cites W2082769632 @default.
• W2857891436 cites W2083355748 @default.
• W2857891436 cites W2085869998 @default.
• W2857891436 cites W2086358447 @default.
• W2857891436 cites W2091611659 @default.
• W2857891436 cites W2092977508 @default.
• W2857891436 cites W2093587943 @default.
• W2857891436 cites W2103395240 @default.
• W2857891436 cites W2112163839 @default.
• W2857891436 cites W2116816846 @default.
• W2857891436 cites W2119454234 @default.
• W2857891436 cites W2125050249 @default.
• W2857891436 cites W2125682019 @default.
• W2857891436 cites W2128105061 @default.
• W2857891436 cites W2135723226 @default.
• W2857891436 cites W2154099646 @default.
• W2857891436 cites W2158612829 @default.
• W2857891436 cites W2161563874 @default.
• W2857891436 cites W2168880991 @default.
• W2857891436 cites W2173921689 @default.
• W2857891436 cites W2211217408 @default.
• W2857891436 cites W2230182184 @default.
• W2857891436 cites W2270913536 @default.
• W2857891436 cites W2292860807 @default.
• W2857891436 cites W2315996519 @default.
• W2857891436 cites W2319240715 @default.
• W2857891436 cites W2479114389 @default.
• W2857891436 cites W2491099585 @default.
• W2857891436 cites W2511722746 @default.
• W2857891436 cites W2521173581 @default.
• W2857891436 cites W2528749980 @default.
• W2857891436 cites W2534943943 @default.
• W2857891436 cites W2557931062 @default.
• W2857891436 cites W2562531072 @default.
• W2857891436 cites W2615232154 @default.
• W2857891436 cites W2622983518 @default.
• W2857891436 cites W2752777408 @default.
• W2857891436 cites W783001870 @default.
• W2857891436 doi "https://doi.org/10.1523/jneurosci.0545-18.2018" @default.
• W2857891436 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6096046" @default.
• W2857891436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29976624" @default.
• W2857891436 hasPublicationYear "2018" @default.
• W2857891436 type Work @default.
• W2857891436 sameAs 2857891436 @default.
• W2857891436 citedByCount "28" @default.
• W2857891436 countsByYear W28578914362019 @default.
• W2857891436 countsByYear W28578914362020 @default.

• next