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• W285832136 endingPage "148" @default.
• W285832136 startingPage "89" @default.
• W285832136 abstract "Publisher Summary This chapter reveals that the generation of rhythmical heartbeats in mammals has been considered essentially myogenic, resulting from slow diastolic depolarization of pacemaker cells or from subthreshold oscillations of their membrane potentials. The role of the nervous system is often restricted to an external modulation of the inherent muscular pacemaker. This situation results from the fact that current knowledge of cardiac innervation of the mammalian heart has been derived from classical, physiological, and microanatomical observations. According to these studies, the pacemaker area of the heart receives abundant cholinergic and adrenergic postganglionics originating from the extracardiac ganglia. A majority of the ganglionic cells is concentrated in the subepicardium of the base of the heart, around the ostia of great vessels and in the coronary sulcus, where they form more or less delimitated subepicardial ganglia. Isolated ganglionic cells can also be found scattered in the meshes of the terminal nerve plexus located in the wall of the right atrium and in the interatrial septum all along the sulcus terminalis." @default.
• W285832136 created "2016-06-24" @default.
• W285832136 creator A5007394721 @default.
• W285832136 creator A5010957728 @default.
• W285832136 date "1987-01-01" @default.
• W285832136 modified "2023-09-25" @default.
• W285832136 title "Intrinsic Nerve Plexus of Mammalian Heart: Morphological Basis of Cardiac Rhythmical Activity?" @default.
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