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- W28637760 abstract "Publisher Summary This chapter describes the cell line of Hodgkin's disease. The cell of origin in Hodgkin's disease is most likely lymphoid—either an early T or B cell or a common precursor. All of the established Hodgkin's cell lines and a considerable percentage of primary tumor cells have incomplete immunoglobulin or T cell receptor rearrangements. The immunophenotype of in vivo and in vitro Hodgkin's cells, although representing a more differentiated lymphoid state, is well in line with this hypothesis. The heterogeneity of results from histology, immunophenotype, genotype, oncogene expression, and viral infection studies suggests that there may be more than one cell of origin. Hodgkin's disease may be a group of biologically closely related diseases linked by symptoms and histology that derive from more than one nonmalignant cell type." @default.
- W28637760 created "2016-06-24" @default.
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- W28637760 date "1992-01-01" @default.
- W28637760 modified "2023-10-10" @default.
- W28637760 title "Hodgkin's Disease: Analysis of Cell Line Data" @default.
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- W28637760 doi "https://doi.org/10.1016/b978-0-12-364933-1.50013-8" @default.
- W28637760 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1310296" @default.
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