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- W286443742 abstract "Endocrine disorders can influence the haemosta- tic balance. Abnormal coagulation test results have been observed in patients with abnormal hormone levels. Also unprovoked bleeding or thrombotic events have been asso- ciated with endocrine disease. The aim of the present review is to summarise the available evidence on the influ- ence of common endocrine disorders on the coagulation system, and their possible clinical implications. We focus on thyroid dysfunction, hyper- and hypocortisolism and growth hormone disturbances, while other endocrine dis- orders are only briefly discussed. In the published litera- ture a clear bleeding diathesis has only been associated with overt hypothyroidism, mainly mediated by an acquired von Willebrand syndrome. A clinically relevant hypercoagulable state may be present in patients with hyperthyroidism, hypercortisolism or abnormal growth hormone levels, but adequate prospective clinical studies are lacking. Also effects of pheochromocytoma, hyperpro- lactinaemia and hyperaldosteronism on the coagulation" @default.
- W286443742 created "2016-06-24" @default.
- W286443742 creator A5014107975 @default.
- W286443742 creator A5084997106 @default.
- W286443742 date "2007-01-01" @default.
- W286443742 modified "2023-09-27" @default.
- W286443742 title "A. SquizzatoV.E.A. GerdesW. AgenoH.R. Büller The coagulation system in endocrine disorders: a narrative review" @default.
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