Matches in SemOpenAlex for { <https://semopenalex.org/work/W2865859501> ?p ?o ?g. }
- W2865859501 endingPage "757" @default.
- W2865859501 startingPage "751" @default.
- W2865859501 abstract "Marine shellfish provides a series of biofunctionality account of its high-protein level. In this study, the osteogenic effect of a novel peptide, YRGDVVPK, from Crassostrea gigas protein hydrolysates on preosteoblast MC3T3-E1 proliferation was examined. Synthetic peptide with 100 nM significantly promoted the proliferation of MC3T3-E1 cells for a treatment of 72 h assayed by MTT method, and which was confirmed by the increase of alkaline phosphatase (ALP) activity. The peptide, YRGDVVPK, was docked with integrin α5β1 (PDB ID: 3VI4), which is a surface receptor of MC3T3-E1. The interaction of the peptide with integrin α5β1 (PDB ID: 3VI4) was analyzed by the molecular modeling algorithm of CDOCKER, which showed a more stable combination than the original ligand. The results suggested the novel peptide could promote the preosteoblast MC3T3-E1 proliferation probably by activating the signaling pathway of MAPK, which is induced through binding with peptide YRGDVVPK." @default.
- W2865859501 created "2018-07-19" @default.
- W2865859501 creator A5009168601 @default.
- W2865859501 creator A5011090841 @default.
- W2865859501 creator A5017777141 @default.
- W2865859501 creator A5030825527 @default.
- W2865859501 creator A5058643741 @default.
- W2865859501 creator A5059651600 @default.
- W2865859501 creator A5078580577 @default.
- W2865859501 date "2019-01-01" @default.
- W2865859501 modified "2023-10-03" @default.
- W2865859501 title "Identification and mechanism evaluation of a novel osteogenesis promoting peptide from Tubulin Alpha-1C chain in Crassostrea gigas" @default.
- W2865859501 cites W126207357 @default.
- W2865859501 cites W1860209526 @default.
- W2865859501 cites W1864016981 @default.
- W2865859501 cites W1963826675 @default.
- W2865859501 cites W1984148608 @default.
- W2865859501 cites W1991343378 @default.
- W2865859501 cites W2002121674 @default.
- W2865859501 cites W2015839100 @default.
- W2865859501 cites W2017326100 @default.
- W2865859501 cites W2026345779 @default.
- W2865859501 cites W2036908471 @default.
- W2865859501 cites W2046723789 @default.
- W2865859501 cites W2063859419 @default.
- W2865859501 cites W2071068562 @default.
- W2865859501 cites W2076064293 @default.
- W2865859501 cites W2079662419 @default.
- W2865859501 cites W2085076969 @default.
- W2865859501 cites W2093974041 @default.
- W2865859501 cites W2094469836 @default.
- W2865859501 cites W2106917100 @default.
- W2865859501 cites W2113550007 @default.
- W2865859501 cites W2131304737 @default.
- W2865859501 cites W2153724762 @default.
- W2865859501 cites W2156053468 @default.
- W2865859501 cites W2335178464 @default.
- W2865859501 cites W2444283900 @default.
- W2865859501 cites W2524209852 @default.
- W2865859501 cites W2556534571 @default.
- W2865859501 cites W2595298045 @default.
- W2865859501 cites W2605018009 @default.
- W2865859501 cites W2609365942 @default.
- W2865859501 cites W2617969304 @default.
- W2865859501 cites W2729013931 @default.
- W2865859501 cites W2756087218 @default.
- W2865859501 cites W2756261377 @default.
- W2865859501 cites W2758856411 @default.
- W2865859501 cites W2778176500 @default.
- W2865859501 doi "https://doi.org/10.1016/j.foodchem.2018.07.063" @default.
- W2865859501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30309606" @default.
- W2865859501 hasPublicationYear "2019" @default.
- W2865859501 type Work @default.
- W2865859501 sameAs 2865859501 @default.
- W2865859501 citedByCount "29" @default.
- W2865859501 countsByYear W28658595012019 @default.
- W2865859501 countsByYear W28658595012020 @default.
- W2865859501 countsByYear W28658595012021 @default.
- W2865859501 countsByYear W28658595012022 @default.
- W2865859501 countsByYear W28658595012023 @default.
- W2865859501 crossrefType "journal-article" @default.
- W2865859501 hasAuthorship W2865859501A5009168601 @default.
- W2865859501 hasAuthorship W2865859501A5011090841 @default.
- W2865859501 hasAuthorship W2865859501A5017777141 @default.
- W2865859501 hasAuthorship W2865859501A5030825527 @default.
- W2865859501 hasAuthorship W2865859501A5058643741 @default.
- W2865859501 hasAuthorship W2865859501A5059651600 @default.
- W2865859501 hasAuthorship W2865859501A5078580577 @default.
- W2865859501 hasConcept C104317684 @default.
- W2865859501 hasConcept C10858879 @default.
- W2865859501 hasConcept C153911025 @default.
- W2865859501 hasConcept C160160445 @default.
- W2865859501 hasConcept C167625842 @default.
- W2865859501 hasConcept C181199279 @default.
- W2865859501 hasConcept C185592680 @default.
- W2865859501 hasConcept C2779281246 @default.
- W2865859501 hasConcept C55493867 @default.
- W2865859501 hasConcept C65556437 @default.
- W2865859501 hasConcept C86803240 @default.
- W2865859501 hasConcept C95444343 @default.
- W2865859501 hasConceptScore W2865859501C104317684 @default.
- W2865859501 hasConceptScore W2865859501C10858879 @default.
- W2865859501 hasConceptScore W2865859501C153911025 @default.
- W2865859501 hasConceptScore W2865859501C160160445 @default.
- W2865859501 hasConceptScore W2865859501C167625842 @default.
- W2865859501 hasConceptScore W2865859501C181199279 @default.
- W2865859501 hasConceptScore W2865859501C185592680 @default.
- W2865859501 hasConceptScore W2865859501C2779281246 @default.
- W2865859501 hasConceptScore W2865859501C55493867 @default.
- W2865859501 hasConceptScore W2865859501C65556437 @default.
- W2865859501 hasConceptScore W2865859501C86803240 @default.
- W2865859501 hasConceptScore W2865859501C95444343 @default.
- W2865859501 hasFunder F4320321001 @default.
- W2865859501 hasLocation W28658595011 @default.
- W2865859501 hasLocation W28658595012 @default.
- W2865859501 hasOpenAccess W2865859501 @default.
- W2865859501 hasPrimaryLocation W28658595011 @default.
- W2865859501 hasRelatedWork W1917535562 @default.