Matches in SemOpenAlex for { <https://semopenalex.org/work/W2867137060> ?p ?o ?g. }
- W2867137060 abstract "Background: Heart failure (HF) is a severe public health problem because of its high morbidity and mortality and elevated costs, thus requiring better understanding of its course. In its complex and multifactorial pathogenesis, sympathetic hyperactivity plays a relevant role. Considering that sympathetic dysfunction is already present in the initial phases of chronic Chagas cardiomyopathy (CCC) and frequently associated with a worse prognosis, we assumed it could be more severe in CCC than in cardiomyopathies of other etiologies (non-CCC). Objectives: To assess the cardiac sympathetic dysfunction 123I-MIBG) of HF, comparing individuals with CCC to those with non-CCC, using heart transplant (HT) patients as denervated heart parameters. Methods: We assessed 76 patients with functional class II-VI HF, being 25 CCC (17 men), 25 non-CCC (14 men) and 26 HT (20 men), by use of cardiac 123I-metaiodobenzylguanidine 123I-MIBG) scintigraphy, estimating the early and late heart-to-mediastinum ratio (HMR) of 123I-MIBG uptake and cardiac washout (WO%). The 5% significance level was adopted in the statistical analysis. Results: The early and late HMR values were 1.73 ± 0.24 and 1.58 ± 0.27, respectively, in CCC, and 1.62 ± 0.21 and 1.44 ± 0.16 in non-CCC (p = NS), being, however, higher in HT patients (p < 0.001). The WO% values were 41.65 ± 21.4 (CCC), 47.37 ± 14.19% (non-CCC) and 43.29 ± 23.02 (HT), p = 0.057. The late HMR values showed a positive weak correlation with left ventricular ejection fraction (LVEF) in CCC and non-CCC (r = 0.42 and p = 0.045; and r = 0.49 and p = 0.015, respectively). Conclusion: Sympathetic hyperactivity 123I-MIBG) was evidenced in patients with class II-IV HF, LVEF < 45%, independently of the HF etiology, as compared to HT patients." @default.
- W2867137060 created "2018-07-19" @default.
- W2867137060 creator A5038066626 @default.
- W2867137060 creator A5038697856 @default.
- W2867137060 creator A5038882711 @default.
- W2867137060 creator A5042345155 @default.
- W2867137060 creator A5062413608 @default.
- W2867137060 creator A5088251642 @default.
- W2867137060 date "2018-01-01" @default.
- W2867137060 modified "2023-10-03" @default.
- W2867137060 title "Sympathetic Dysautonomia in Heart Failure by 123I-MIBG: comparison between Chagasic, non-Chagasic and heart transplant patients" @default.
- W2867137060 cites W155312217 @default.
- W2867137060 cites W1930119086 @default.
- W2867137060 cites W1970427540 @default.
- W2867137060 cites W1974276617 @default.
- W2867137060 cites W1984872916 @default.
- W2867137060 cites W1986517868 @default.
- W2867137060 cites W1987772155 @default.
- W2867137060 cites W2038706259 @default.
- W2867137060 cites W2051416889 @default.
- W2867137060 cites W2051837315 @default.
- W2867137060 cites W2056278535 @default.
- W2867137060 cites W2061693585 @default.
- W2867137060 cites W2064785587 @default.
- W2867137060 cites W2074429652 @default.
- W2867137060 cites W2088905205 @default.
- W2867137060 cites W2089821017 @default.
- W2867137060 cites W2092852829 @default.
- W2867137060 cites W2094065595 @default.
- W2867137060 cites W2094903337 @default.
- W2867137060 cites W2095642043 @default.
- W2867137060 cites W2097757382 @default.
- W2867137060 cites W2100133714 @default.
- W2867137060 cites W2111148563 @default.
- W2867137060 cites W2124624517 @default.
- W2867137060 cites W2129118390 @default.
- W2867137060 cites W2157230315 @default.
- W2867137060 cites W2168048360 @default.
- W2867137060 cites W2170304291 @default.
- W2867137060 cites W2182213677 @default.
- W2867137060 cites W2401609064 @default.
- W2867137060 cites W2470227528 @default.
- W2867137060 cites W3187107430 @default.
- W2867137060 cites W3771626 @default.
- W2867137060 cites W4249896096 @default.
- W2867137060 doi "https://doi.org/10.5935/abc.20180124" @default.
- W2867137060 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6122917" @default.
- W2867137060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30088556" @default.
- W2867137060 hasPublicationYear "2018" @default.
- W2867137060 type Work @default.
- W2867137060 sameAs 2867137060 @default.
- W2867137060 citedByCount "3" @default.
- W2867137060 countsByYear W28671370602021 @default.
- W2867137060 crossrefType "journal-article" @default.
- W2867137060 hasAuthorship W2867137060A5038066626 @default.
- W2867137060 hasAuthorship W2867137060A5038697856 @default.
- W2867137060 hasAuthorship W2867137060A5038882711 @default.
- W2867137060 hasAuthorship W2867137060A5042345155 @default.
- W2867137060 hasAuthorship W2867137060A5062413608 @default.
- W2867137060 hasAuthorship W2867137060A5088251642 @default.
- W2867137060 hasBestOaLocation W28671370601 @default.
- W2867137060 hasConcept C112418997 @default.
- W2867137060 hasConcept C126322002 @default.
- W2867137060 hasConcept C137627325 @default.
- W2867137060 hasConcept C142724271 @default.
- W2867137060 hasConcept C164705383 @default.
- W2867137060 hasConcept C2778198053 @default.
- W2867137060 hasConcept C2778797674 @default.
- W2867137060 hasConcept C2778849806 @default.
- W2867137060 hasConcept C2779902710 @default.
- W2867137060 hasConcept C71924100 @default.
- W2867137060 hasConcept C78085059 @default.
- W2867137060 hasConceptScore W2867137060C112418997 @default.
- W2867137060 hasConceptScore W2867137060C126322002 @default.
- W2867137060 hasConceptScore W2867137060C137627325 @default.
- W2867137060 hasConceptScore W2867137060C142724271 @default.
- W2867137060 hasConceptScore W2867137060C164705383 @default.
- W2867137060 hasConceptScore W2867137060C2778198053 @default.
- W2867137060 hasConceptScore W2867137060C2778797674 @default.
- W2867137060 hasConceptScore W2867137060C2778849806 @default.
- W2867137060 hasConceptScore W2867137060C2779902710 @default.
- W2867137060 hasConceptScore W2867137060C71924100 @default.
- W2867137060 hasConceptScore W2867137060C78085059 @default.
- W2867137060 hasLocation W28671370601 @default.
- W2867137060 hasLocation W28671370602 @default.
- W2867137060 hasLocation W28671370603 @default.
- W2867137060 hasLocation W28671370604 @default.
- W2867137060 hasLocation W28671370605 @default.
- W2867137060 hasOpenAccess W2867137060 @default.
- W2867137060 hasPrimaryLocation W28671370601 @default.
- W2867137060 hasRelatedWork W2051712573 @default.
- W2867137060 hasRelatedWork W2077083067 @default.
- W2867137060 hasRelatedWork W2091139515 @default.
- W2867137060 hasRelatedWork W2167036398 @default.
- W2867137060 hasRelatedWork W2355594703 @default.
- W2867137060 hasRelatedWork W2361407492 @default.
- W2867137060 hasRelatedWork W2538662566 @default.
- W2867137060 hasRelatedWork W2965474825 @default.
- W2867137060 hasRelatedWork W3033076790 @default.
- W2867137060 hasRelatedWork W4382048704 @default.