Matches in SemOpenAlex for { <https://semopenalex.org/work/W2875787712> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2875787712 abstract "Objective: Oral cancer is the most common forms of malignancy diagnosed in men and women and the mortality rate is very high in the developing countries. Therefore, the study was conducted to evaluate the potential role of Myristica fragrans Houtt (mace) acetone extract (MAE) on experimentally induced oral cancer in rats.Methods: Oral cancer was experimentally induced to rats by administering 4NQO (carcinogenic agent) at a concentration of 30 ppm in drinking water and treated with three different doses of mace extract (100, 250, 500mg/kg body weight) dissolved in water and given orally as a single dose and another group treated with the standard 5-fluorouracil for 14 weeks.Results: All the experimental groups had an incremental weight gain, except NQO alone induced group showed body weight loss and also showed low survival rate denoting the NQO carcinogenic toxicity in them. The exophytic tumor volume showed gradual increase and reached 30 mm3 at the 14 weeks time point. Tumor incidence and tumor multiplicity values of mace extract treatment (100, 250, 500 mg/kg body weight) showed gradual reduction in the size of tumor significantly compared with that of the standard drug. The histopathological examination of oral tumor mucosal tissue illustrated well differentiated squamous cell carcinoma in NQO induced group and also declining the risk of carcinoma changes in MAE treated groups.Conclusions: These experimental results unveil that MAE possesses effective role in curing oral cancer." @default.
- W2875787712 created "2018-07-19" @default.
- W2875787712 creator A5040236951 @default.
- W2875787712 creator A5054714549 @default.
- W2875787712 creator A5059431459 @default.
- W2875787712 creator A5081939049 @default.
- W2875787712 date "2018-07-07" @default.
- W2875787712 modified "2023-09-23" @default.
- W2875787712 title "ANTICANCER STUDY OF MYRISTICA FRAGRANS HOUTT. (MACE) EXTRACT ON 4-NITROQUINOLINE-1-OXIDE-INDUCED ORAL CANCER IN RATS" @default.
- W2875787712 doi "https://doi.org/10.22159/ajpcr.2018.v11i7.25363" @default.
- W2875787712 hasPublicationYear "2018" @default.
- W2875787712 type Work @default.
- W2875787712 sameAs 2875787712 @default.
- W2875787712 citedByCount "0" @default.
- W2875787712 crossrefType "journal-article" @default.
- W2875787712 hasAuthorship W2875787712A5040236951 @default.
- W2875787712 hasAuthorship W2875787712A5054714549 @default.
- W2875787712 hasAuthorship W2875787712A5059431459 @default.
- W2875787712 hasAuthorship W2875787712A5081939049 @default.
- W2875787712 hasBestOaLocation W28757877121 @default.
- W2875787712 hasConcept C114246631 @default.
- W2875787712 hasConcept C121608353 @default.
- W2875787712 hasConcept C126322002 @default.
- W2875787712 hasConcept C147583825 @default.
- W2875787712 hasConcept C185592680 @default.
- W2875787712 hasConcept C2776841633 @default.
- W2875787712 hasConcept C2778512257 @default.
- W2875787712 hasConcept C2780739214 @default.
- W2875787712 hasConcept C33070731 @default.
- W2875787712 hasConcept C45393284 @default.
- W2875787712 hasConcept C500558357 @default.
- W2875787712 hasConcept C501593827 @default.
- W2875787712 hasConcept C55493867 @default.
- W2875787712 hasConcept C556039675 @default.
- W2875787712 hasConcept C71924100 @default.
- W2875787712 hasConcept C86803240 @default.
- W2875787712 hasConcept C90924648 @default.
- W2875787712 hasConcept C98274493 @default.
- W2875787712 hasConceptScore W2875787712C114246631 @default.
- W2875787712 hasConceptScore W2875787712C121608353 @default.
- W2875787712 hasConceptScore W2875787712C126322002 @default.
- W2875787712 hasConceptScore W2875787712C147583825 @default.
- W2875787712 hasConceptScore W2875787712C185592680 @default.
- W2875787712 hasConceptScore W2875787712C2776841633 @default.
- W2875787712 hasConceptScore W2875787712C2778512257 @default.
- W2875787712 hasConceptScore W2875787712C2780739214 @default.
- W2875787712 hasConceptScore W2875787712C33070731 @default.
- W2875787712 hasConceptScore W2875787712C45393284 @default.
- W2875787712 hasConceptScore W2875787712C500558357 @default.
- W2875787712 hasConceptScore W2875787712C501593827 @default.
- W2875787712 hasConceptScore W2875787712C55493867 @default.
- W2875787712 hasConceptScore W2875787712C556039675 @default.
- W2875787712 hasConceptScore W2875787712C71924100 @default.
- W2875787712 hasConceptScore W2875787712C86803240 @default.
- W2875787712 hasConceptScore W2875787712C90924648 @default.
- W2875787712 hasConceptScore W2875787712C98274493 @default.
- W2875787712 hasLocation W28757877121 @default.
- W2875787712 hasOpenAccess W2875787712 @default.
- W2875787712 hasPrimaryLocation W28757877121 @default.
- W2875787712 hasRelatedWork W1967984107 @default.
- W2875787712 hasRelatedWork W1989931001 @default.
- W2875787712 hasRelatedWork W1996794421 @default.
- W2875787712 hasRelatedWork W2165105462 @default.
- W2875787712 hasRelatedWork W2316274201 @default.
- W2875787712 hasRelatedWork W2875787712 @default.
- W2875787712 hasRelatedWork W2899084033 @default.
- W2875787712 hasRelatedWork W2920328101 @default.
- W2875787712 hasRelatedWork W3014796486 @default.
- W2875787712 hasRelatedWork W3181034254 @default.
- W2875787712 isParatext "false" @default.
- W2875787712 isRetracted "false" @default.
- W2875787712 magId "2875787712" @default.
- W2875787712 workType "article" @default.