FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2876322013> ?p ?o ?g. }

• W2876322013 endingPage "1305" @default.
• W2876322013 startingPage "1300" @default.
• W2876322013 abstract "A number of pathogenic bacteria reproduce inside mammalian cells and are thus inaccessible to many antimicrobial drugs. Herein, we present a facile method to a focused library of antibacterial agents known as cationic amphiphilic polyproline helices (CAPHs). We identified three CAPHs from the library with superior cell penetration within macrophages and excellent antibacterial action against both Gram-positive and Gram-negative bacteria. These cell-penetrating antibacterial CAPHs have specific subcellular localizations that allow for targeting of pathogenic bacteria at their intracellular niches, a unique feature that promotes the successful clearance of intracellular pathogens (Salmonella, Shigella, and Listeria) residing within macrophages. Furthermore, the selected CAPHs also significantly reduced bacterial infections in an in vivo model of Caenorhabditis elegans, with minimal in vivo toxicity." @default.
• W2876322013 created "2018-07-19" @default.
• W2876322013 creator A5001785092 @default.
• W2876322013 creator A5018239576 @default.
• W2876322013 creator A5026553668 @default.
• W2876322013 creator A5039949898 @default.
• W2876322013 creator A5051420549 @default.
• W2876322013 creator A5080452920 @default.
• W2876322013 creator A5082535868 @default.
• W2876322013 date "2018-07-06" @default.
• W2876322013 modified "2023-10-17" @default.
• W2876322013 title "A Library Approach to Cationic Amphiphilic Polyproline Helices that Target Intracellular Pathogenic Bacteria" @default.
• W2876322013 cites W1915856409 @default.
• W2876322013 cites W1983843529 @default.
• W2876322013 cites W2002047195 @default.
• W2876322013 cites W2005349464 @default.
• W2876322013 cites W2014644290 @default.
• W2876322013 cites W2021024902 @default.
• W2876322013 cites W2021702515 @default.
• W2876322013 cites W2039808886 @default.
• W2876322013 cites W2055411163 @default.
• W2876322013 cites W2064809559 @default.
• W2876322013 cites W2078006689 @default.
• W2876322013 cites W2083651925 @default.
• W2876322013 cites W2086506975 @default.
• W2876322013 cites W2090484064 @default.
• W2876322013 cites W2091800702 @default.
• W2876322013 cites W2097006899 @default.
• W2876322013 cites W2100266303 @default.
• W2876322013 cites W2101997581 @default.
• W2876322013 cites W2122627499 @default.
• W2876322013 cites W2156322493 @default.
• W2876322013 cites W2162573988 @default.
• W2876322013 cites W2293153195 @default.
• W2876322013 cites W2412131977 @default.
• W2876322013 cites W2476482095 @default.
• W2876322013 cites W2490801896 @default.
• W2876322013 cites W2514833799 @default.
• W2876322013 doi "https://doi.org/10.1021/acsinfecdis.8b00124" @default.
• W2876322013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29979033" @default.
• W2876322013 hasPublicationYear "2018" @default.
• W2876322013 type Work @default.
• W2876322013 sameAs 2876322013 @default.
• W2876322013 citedByCount "8" @default.
• W2876322013 countsByYear W28763220132019 @default.
• W2876322013 countsByYear W28763220132020 @default.
• W2876322013 countsByYear W28763220132021 @default.
• W2876322013 countsByYear W28763220132022 @default.
• W2876322013 crossrefType "journal-article" @default.
• W2876322013 hasAuthorship W2876322013A5001785092 @default.
• W2876322013 hasAuthorship W2876322013A5018239576 @default.
• W2876322013 hasAuthorship W2876322013A5026553668 @default.
• W2876322013 hasAuthorship W2876322013A5039949898 @default.
• W2876322013 hasAuthorship W2876322013A5051420549 @default.
• W2876322013 hasAuthorship W2876322013A5080452920 @default.
• W2876322013 hasAuthorship W2876322013A5082535868 @default.
• W2876322013 hasConcept C104317684 @default.
• W2876322013 hasConcept C109300003 @default.
• W2876322013 hasConcept C150903083 @default.
• W2876322013 hasConcept C153726182 @default.
• W2876322013 hasConcept C185592680 @default.
• W2876322013 hasConcept C19655278 @default.
• W2876322013 hasConcept C207001950 @default.
• W2876322013 hasConcept C2778883795 @default.
• W2876322013 hasConcept C2779281246 @default.
• W2876322013 hasConcept C2780104969 @default.
• W2876322013 hasConcept C2781217973 @default.
• W2876322013 hasConcept C4937899 @default.
• W2876322013 hasConcept C523546767 @default.
• W2876322013 hasConcept C540938839 @default.
• W2876322013 hasConcept C54355233 @default.
• W2876322013 hasConcept C547475151 @default.
• W2876322013 hasConcept C55493867 @default.
• W2876322013 hasConcept C79879829 @default.
• W2876322013 hasConcept C86803240 @default.
• W2876322013 hasConcept C89423630 @default.
• W2876322013 hasConcept C95444343 @default.
• W2876322013 hasConceptScore W2876322013C104317684 @default.
• W2876322013 hasConceptScore W2876322013C109300003 @default.
• W2876322013 hasConceptScore W2876322013C150903083 @default.
• W2876322013 hasConceptScore W2876322013C153726182 @default.
• W2876322013 hasConceptScore W2876322013C185592680 @default.
• W2876322013 hasConceptScore W2876322013C19655278 @default.
• W2876322013 hasConceptScore W2876322013C207001950 @default.
• W2876322013 hasConceptScore W2876322013C2778883795 @default.
• W2876322013 hasConceptScore W2876322013C2779281246 @default.
• W2876322013 hasConceptScore W2876322013C2780104969 @default.
• W2876322013 hasConceptScore W2876322013C2781217973 @default.
• W2876322013 hasConceptScore W2876322013C4937899 @default.
• W2876322013 hasConceptScore W2876322013C523546767 @default.
• W2876322013 hasConceptScore W2876322013C540938839 @default.
• W2876322013 hasConceptScore W2876322013C54355233 @default.
• W2876322013 hasConceptScore W2876322013C547475151 @default.
• W2876322013 hasConceptScore W2876322013C55493867 @default.
• W2876322013 hasConceptScore W2876322013C79879829 @default.
• W2876322013 hasConceptScore W2876322013C86803240 @default.
• W2876322013 hasConceptScore W2876322013C89423630 @default.
• W2876322013 hasConceptScore W2876322013C95444343 @default.

• next