FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2879665038> ?p ?o ?g. }

• W2879665038 abstract "Foot-and-mouth disease (FMD), caused by FMD virus (FMDV; Aphthovirus, Picornaviridae), is a highly contagious and economically important disease of cloven-hoofed domestic livestock and wildlife species worldwide. Subsequent to the clinical phase of FMD, a large proportion of FMDV-infected ruminants become persistently infected carriers, defined by detection of FMDV in oropharyngeal fluid (OPF) samples 28 days or more post-infection. The goal of this prospective study was to characterize the FMD carrier state in cattle subsequent to natural infection under typical husbandry practices in Vietnam. Ten persistently infected cattle on eight farms in the Long An province in southern Vietnam were monitored by monthly screening of serum and oropharyngeal fluid samples for 12 months. To assess transmission from FMDV carriers, sixteen naïve cattle were intentionally brought into direct contact with the persistently infected animals for six months, and were monitored by clinical and laboratory methods. The restricted mean duration of the FMD carrier state was 27.7 months, and the rate of decrease of the proportion of carrier animals was 0.03 per month. There was no evidence of transmission to naïve animals throughout the study period. Additionally, there was no detection of FMDV infection or seroconversion in three calves born to carrier animals during the study. The force of infection for carrier-to-contact transmission was 0 per month, with upper 95% confidence limit of 0.064 per month. Phylogenetic analysis of viral protein 1 (VP1) coding sequences obtained from carriers indicated that all viruses recovered in this study belonged to the O/ME-SA/PanAsia lineage, and grouped phylogenetically with temporally and geographically related viruses. Analysis of within-host evolution of FMDV, based upon full-length open reading frame sequences recovered from consecutive samples from one animal, indicated that most of the non-synonymous changes occurred in Lpro, VP2, and VP3 protein coding regions. This study suggests that the duration of FMDV persistent infection in cattle may be longer than previously recognized, but the risk of transmission is low. Additional novel insights are provided into within-host viral evolution under natural conditions in an endemic setting." @default.
• W2879665038 created "2018-07-19" @default.
• W2879665038 creator A5005650469 @default.
• W2879665038 creator A5010188320 @default.
• W2879665038 creator A5011805768 @default.
• W2879665038 creator A5018652250 @default.
• W2879665038 creator A5031175276 @default.
• W2879665038 creator A5031592461 @default.
• W2879665038 creator A5033774865 @default.
• W2879665038 creator A5034766329 @default.
• W2879665038 creator A5037216646 @default.
• W2879665038 creator A5040513308 @default.
• W2879665038 creator A5045825700 @default.
• W2879665038 creator A5064680888 @default.
• W2879665038 creator A5064832957 @default.
• W2879665038 creator A5065713469 @default.
• W2879665038 creator A5069908271 @default.
• W2879665038 creator A5084311137 @default.
• W2879665038 creator A5086495875 @default.
• W2879665038 date "2018-07-27" @default.
• W2879665038 modified "2023-09-26" @default.
• W2879665038 title "Lack of Transmission of Foot-and-Mouth Disease Virus From Persistently Infected Cattle to Naïve Cattle Under Field Conditions in Vietnam" @default.
• W2879665038 cites W1493610845 @default.
• W2879665038 cites W1503415480 @default.
• W2879665038 cites W1506465971 @default.
• W2879665038 cites W1513186671 @default.
• W2879665038 cites W1604386352 @default.
• W2879665038 cites W1757744415 @default.
• W2879665038 cites W1760426601 @default.
• W2879665038 cites W182479813 @default.
• W2879665038 cites W1840781779 @default.
• W2879665038 cites W1932619527 @default.
• W2879665038 cites W1966290164 @default.
• W2879665038 cites W1969789133 @default.
• W2879665038 cites W1970491106 @default.
• W2879665038 cites W1975082608 @default.
• W2879665038 cites W1981595474 @default.
• W2879665038 cites W1983549036 @default.
• W2879665038 cites W1996261922 @default.
• W2879665038 cites W1998148929 @default.
• W2879665038 cites W2004425593 @default.
• W2879665038 cites W2006687335 @default.
• W2879665038 cites W2025380368 @default.
• W2879665038 cites W2032206789 @default.
• W2879665038 cites W2034108578 @default.
• W2879665038 cites W2043484615 @default.
• W2879665038 cites W2061134362 @default.
• W2879665038 cites W2065424450 @default.
• W2879665038 cites W2067037600 @default.
• W2879665038 cites W2081400429 @default.
• W2879665038 cites W2088448340 @default.
• W2879665038 cites W2090893051 @default.
• W2879665038 cites W2094939159 @default.
• W2879665038 cites W2103738533 @default.
• W2879665038 cites W2107108193 @default.
• W2879665038 cites W2120642614 @default.
• W2879665038 cites W2125121305 @default.
• W2879665038 cites W2128151337 @default.
• W2879665038 cites W2130362098 @default.
• W2879665038 cites W2144775551 @default.
• W2879665038 cites W2146714484 @default.
• W2879665038 cites W2153432740 @default.
• W2879665038 cites W2153855413 @default.
• W2879665038 cites W2159317368 @default.
• W2879665038 cites W2164418313 @default.
• W2879665038 cites W2166552539 @default.
• W2879665038 cites W2169112867 @default.
• W2879665038 cites W2170488570 @default.
• W2879665038 cites W2184025199 @default.
• W2879665038 cites W2264675815 @default.
• W2879665038 cites W2294951422 @default.
• W2879665038 cites W2346606452 @default.
• W2879665038 cites W2399372309 @default.
• W2879665038 cites W2414484832 @default.
• W2879665038 cites W2473612325 @default.
• W2879665038 cites W2473636172 @default.
• W2879665038 cites W2478539902 @default.
• W2879665038 cites W2520019527 @default.
• W2879665038 cites W2531508693 @default.
• W2879665038 cites W2592237168 @default.
• W2879665038 cites W2605759691 @default.
• W2879665038 cites W2610305774 @default.
• W2879665038 cites W2883835166 @default.
• W2879665038 cites W3194963260 @default.
• W2879665038 cites W4231756443 @default.
• W2879665038 cites W62543144 @default.
• W2879665038 cites W2610359665 @default.
• W2879665038 doi "https://doi.org/10.3389/fvets.2018.00174" @default.
• W2879665038 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6072850" @default.
• W2879665038 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30101147" @default.
• W2879665038 hasPublicationYear "2018" @default.
• W2879665038 type Work @default.
• W2879665038 sameAs 2879665038 @default.
• W2879665038 citedByCount "35" @default.
• W2879665038 countsByYear W28796650382017 @default.
• W2879665038 countsByYear W28796650382018 @default.
• W2879665038 countsByYear W28796650382019 @default.
• W2879665038 countsByYear W28796650382020 @default.
• W2879665038 countsByYear W28796650382021 @default.
• W2879665038 countsByYear W28796650382022 @default.

• next