Matches in SemOpenAlex for { <https://semopenalex.org/work/W2880075897> ?p ?o ?g. }
- W2880075897 abstract "Sex differences in the incidence and severity of respiratory virus infection are widely documented in humans and murine models and correlate with sex biases in numbers and/or functional responses of innate immune cells in homeostasis and lung infection. Similarly, changes in sex hormone levels upon puberty, pregnancy, and menopause/aging are associated with qualitative and quantitative differences in innate immunity. Immune cells express receptors for estrogens (ERα and ERβ), androgens (AR), and progesterone (PR), and experimental manipulation of sex hormone levels or receptors has revealed that sex hormone receptor activity often underlies sex differences in immune cell numbers and/or functional responses in the respiratory tract. While elegant studies have defined mechanistic roles for sex hormones and receptors in innate immune cells, much remains to be learned about the cellular and molecular mechanisms of action of ER, PR, and AR in myeloid cells and innate lymphocytes to promote the initiation and resolution of antiviral immunity in the lung. Here, we review the literature on sex differences and sex hormone regulation in innate immune cells in the lung in homeostasis and upon respiratory virus infection." @default.
- W2880075897 created "2018-07-19" @default.
- W2880075897 creator A5012051319 @default.
- W2880075897 creator A5068510053 @default.
- W2880075897 date "2018-07-20" @default.
- W2880075897 modified "2023-10-10" @default.
- W2880075897 title "Sex Hormones Regulate Innate Immune Cells and Promote Sex Differences in Respiratory Virus Infection" @default.
- W2880075897 cites W1128459793 @default.
- W2880075897 cites W1419695326 @default.
- W2880075897 cites W1479692645 @default.
- W2880075897 cites W1480261066 @default.
- W2880075897 cites W1509766213 @default.
- W2880075897 cites W1512751723 @default.
- W2880075897 cites W1535236030 @default.
- W2880075897 cites W155810853 @default.
- W2880075897 cites W1572727383 @default.
- W2880075897 cites W1580310389 @default.
- W2880075897 cites W1583538373 @default.
- W2880075897 cites W1602464241 @default.
- W2880075897 cites W1668732801 @default.
- W2880075897 cites W1772394217 @default.
- W2880075897 cites W1828298093 @default.
- W2880075897 cites W1874568289 @default.
- W2880075897 cites W1884520053 @default.
- W2880075897 cites W1908861496 @default.
- W2880075897 cites W1930249563 @default.
- W2880075897 cites W1939256882 @default.
- W2880075897 cites W1945859829 @default.
- W2880075897 cites W1963963818 @default.
- W2880075897 cites W1966585724 @default.
- W2880075897 cites W1968530114 @default.
- W2880075897 cites W1968967340 @default.
- W2880075897 cites W1969027216 @default.
- W2880075897 cites W1971749790 @default.
- W2880075897 cites W1971987845 @default.
- W2880075897 cites W1973040027 @default.
- W2880075897 cites W1973916547 @default.
- W2880075897 cites W1973951521 @default.
- W2880075897 cites W1976026025 @default.
- W2880075897 cites W1976173533 @default.
- W2880075897 cites W1977083682 @default.
- W2880075897 cites W1977409527 @default.
- W2880075897 cites W1978761842 @default.
- W2880075897 cites W1980279332 @default.
- W2880075897 cites W1986219680 @default.
- W2880075897 cites W1986628390 @default.
- W2880075897 cites W1987020978 @default.
- W2880075897 cites W1987021738 @default.
- W2880075897 cites W1987188858 @default.
- W2880075897 cites W1989153158 @default.
- W2880075897 cites W1991432514 @default.
- W2880075897 cites W1993679348 @default.
- W2880075897 cites W1995606588 @default.
- W2880075897 cites W1996485467 @default.
- W2880075897 cites W1996968534 @default.
- W2880075897 cites W1998267683 @default.
- W2880075897 cites W1998846885 @default.
- W2880075897 cites W2000086683 @default.
- W2880075897 cites W2000874583 @default.
- W2880075897 cites W2003749750 @default.
- W2880075897 cites W2004181696 @default.
- W2880075897 cites W2009193065 @default.
- W2880075897 cites W2010293505 @default.
- W2880075897 cites W2011987715 @default.
- W2880075897 cites W2014003387 @default.
- W2880075897 cites W2021954043 @default.
- W2880075897 cites W2024085541 @default.
- W2880075897 cites W2024090978 @default.
- W2880075897 cites W2024183493 @default.
- W2880075897 cites W2025773873 @default.
- W2880075897 cites W2026443089 @default.
- W2880075897 cites W2027798298 @default.
- W2880075897 cites W2029397924 @default.
- W2880075897 cites W2029884417 @default.
- W2880075897 cites W2031888860 @default.
- W2880075897 cites W2033340742 @default.
- W2880075897 cites W2036277270 @default.
- W2880075897 cites W2037725361 @default.
- W2880075897 cites W2039520335 @default.
- W2880075897 cites W2039795459 @default.
- W2880075897 cites W2042552774 @default.
- W2880075897 cites W2043558032 @default.
- W2880075897 cites W2044767152 @default.
- W2880075897 cites W2045688706 @default.
- W2880075897 cites W2045938109 @default.
- W2880075897 cites W2047449373 @default.
- W2880075897 cites W2049385791 @default.
- W2880075897 cites W2050838157 @default.
- W2880075897 cites W2056549743 @default.
- W2880075897 cites W2057104059 @default.
- W2880075897 cites W2058747715 @default.
- W2880075897 cites W2064390592 @default.
- W2880075897 cites W2065498595 @default.
- W2880075897 cites W2067085553 @default.
- W2880075897 cites W2069102920 @default.
- W2880075897 cites W2069692204 @default.
- W2880075897 cites W2070785989 @default.
- W2880075897 cites W2072922561 @default.
- W2880075897 cites W2074937083 @default.
- W2880075897 cites W2075101099 @default.