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• W2880696306 abstract "Abstract Background Pulmonary function testing (PFT) is essential for the clinical assessment of respiratory problems. Respiratory inductance plethysmography (RIP) is a non‐invasive method of PFT requiring minimal patient cooperation. RIP measures the volumetric change in the ribcage and abdomen, from which work of breathing (WOB) indices are derived. WOB indices include: phase angle (Ф), percent ribcage (RC%), respiratory rate (RR), and labored breathing index (LBI). Heart rate (HR) is collected separately. Aim The goal of this study was to assess the utility of a newly developed RIP system, the pneu RIP, in an outpatient clinic setting in children with neuromuscular (NM) disease. Method The pneu RIP system measures and displays the WOB indices in real‐time on an iPad display. Forty‐three subjects, 22 NM patients and 21 healthy children (ages: 5‐18 years) were enrolled. Results Patients’ means showed an increase of 119.8% for Ф, 15.7% for LBI, and 19.9% for HR compared with healthy subjects, when adjusted for age and gender. The study found significant differences between the mean values of the healthy subjects and patients in Ф ( P = 0.000), LBI ( P = 0.001), and HR ( P = 0.001). No differences were noted for RC% and RR between groups. Data for Ф in NM patients were diffusely distributed as compared with healthy subjects based on analysis of histograms. Conclusion Non‐invasive pneu RIP testing provided instantaneous PFT results. As compared to healthy subjects, NM patients showed abnormal results with increased markers of thoracoabdominal asynchrony, WOB indices, and biphasic breathing patterns likely resulting from NM weakness." @default.
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• W2880696306 date "2018-07-12" @default.
• W2880696306 modified "2023-10-18" @default.
• W2880696306 title "Measures of respiratory inductance plethysmography (RIP) in children with neuromuscular disease" @default.
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• W2880696306 doi "https://doi.org/10.1002/ppul.24134" @default.
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