Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883010456> ?p ?o ?g. }
- W2883010456 abstract "Abstract In water, amphiphilic block copolymers (BCPs) can self-assemble into various micelle structures depicting curved liquid/liquid interface. Crystallization, which is incommensurate with this curved space, often leads to defect accumulation and renders the structures leaky, undermining their potential biomedical applications. Herein we report using an emulsion-solution crystallization method to control the crystallization of an amphiphilic BCP, poly ( l -lactide acid)- b -poly (ethylene glycol) (PLLA- b -PEG), at curved liquid/liquid interface. The resultant BCP crystalsomes (BCCs) structurally mimic the classical polymersomes and liposomes yet mechanically are more robust thanks to the single crystal-like crystalline PLLA shell. In blood circulation and biodistribution experiments, fluorophore-loaded BCCs show a 24 h circulation half-life and a 8% particle retention in the blood even at 96 h post injection. We further demonstrate that this good performance can be attributed to controlled polymer crystallization and the unique BCC nanostructure." @default.
- W2883010456 created "2018-08-03" @default.
- W2883010456 creator A5013712700 @default.
- W2883010456 creator A5020700381 @default.
- W2883010456 creator A5023527761 @default.
- W2883010456 creator A5029970494 @default.
- W2883010456 creator A5040677507 @default.
- W2883010456 creator A5041486786 @default.
- W2883010456 creator A5047076761 @default.
- W2883010456 creator A5058149224 @default.
- W2883010456 creator A5062074869 @default.
- W2883010456 creator A5062296756 @default.
- W2883010456 creator A5066243130 @default.
- W2883010456 creator A5068653970 @default.
- W2883010456 creator A5070581944 @default.
- W2883010456 creator A5080751811 @default.
- W2883010456 date "2018-08-01" @default.
- W2883010456 modified "2023-10-16" @default.
- W2883010456 title "Block copolymer crystalsomes with an ultrathin shell to extend blood circulation time" @default.
- W2883010456 cites W1835280798 @default.
- W2883010456 cites W1969535658 @default.
- W2883010456 cites W1976673996 @default.
- W2883010456 cites W1978852307 @default.
- W2883010456 cites W1980241490 @default.
- W2883010456 cites W1982231860 @default.
- W2883010456 cites W1985028236 @default.
- W2883010456 cites W1986594185 @default.
- W2883010456 cites W1987769702 @default.
- W2883010456 cites W1989126860 @default.
- W2883010456 cites W1992274284 @default.
- W2883010456 cites W1993420475 @default.
- W2883010456 cites W1996343692 @default.
- W2883010456 cites W2003836812 @default.
- W2883010456 cites W2015729243 @default.
- W2883010456 cites W2032654453 @default.
- W2883010456 cites W2038040314 @default.
- W2883010456 cites W2038216500 @default.
- W2883010456 cites W2038788919 @default.
- W2883010456 cites W2039201937 @default.
- W2883010456 cites W2041201009 @default.
- W2883010456 cites W2044275524 @default.
- W2883010456 cites W2045678504 @default.
- W2883010456 cites W2046926512 @default.
- W2883010456 cites W2047787027 @default.
- W2883010456 cites W2054745605 @default.
- W2883010456 cites W2060830106 @default.
- W2883010456 cites W2060933310 @default.
- W2883010456 cites W2063909696 @default.
- W2883010456 cites W2078926393 @default.
- W2883010456 cites W2086272714 @default.
- W2883010456 cites W2087864086 @default.
- W2883010456 cites W2089776083 @default.
- W2883010456 cites W2094121768 @default.
- W2883010456 cites W2118493266 @default.
- W2883010456 cites W2122887982 @default.
- W2883010456 cites W2130093942 @default.
- W2883010456 cites W2135486162 @default.
- W2883010456 cites W2143463421 @default.
- W2883010456 cites W2145479354 @default.
- W2883010456 cites W2150812319 @default.
- W2883010456 cites W2157614453 @default.
- W2883010456 cites W2161015691 @default.
- W2883010456 cites W2169515956 @default.
- W2883010456 cites W2204817027 @default.
- W2883010456 cites W2219203861 @default.
- W2883010456 cites W2300326943 @default.
- W2883010456 cites W2303426450 @default.
- W2883010456 cites W2314963796 @default.
- W2883010456 cites W2326188833 @default.
- W2883010456 cites W2334919406 @default.
- W2883010456 cites W2409322723 @default.
- W2883010456 cites W2515394036 @default.
- W2883010456 cites W2800316873 @default.
- W2883010456 cites W298125099 @default.
- W2883010456 cites W4211037153 @default.
- W2883010456 cites W4211167067 @default.
- W2883010456 cites W4212814362 @default.
- W2883010456 cites W4255325196 @default.
- W2883010456 doi "https://doi.org/10.1038/s41467-018-05396-x" @default.
- W2883010456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6070537" @default.
- W2883010456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30068976" @default.
- W2883010456 hasPublicationYear "2018" @default.
- W2883010456 type Work @default.
- W2883010456 sameAs 2883010456 @default.
- W2883010456 citedByCount "55" @default.
- W2883010456 countsByYear W28830104562018 @default.
- W2883010456 countsByYear W28830104562019 @default.
- W2883010456 countsByYear W28830104562020 @default.
- W2883010456 countsByYear W28830104562021 @default.
- W2883010456 countsByYear W28830104562022 @default.
- W2883010456 countsByYear W28830104562023 @default.
- W2883010456 crossrefType "journal-article" @default.
- W2883010456 hasAuthorship W2883010456A5013712700 @default.
- W2883010456 hasAuthorship W2883010456A5020700381 @default.
- W2883010456 hasAuthorship W2883010456A5023527761 @default.
- W2883010456 hasAuthorship W2883010456A5029970494 @default.
- W2883010456 hasAuthorship W2883010456A5040677507 @default.
- W2883010456 hasAuthorship W2883010456A5041486786 @default.
- W2883010456 hasAuthorship W2883010456A5047076761 @default.
- W2883010456 hasAuthorship W2883010456A5058149224 @default.