FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883103417> ?p ?o ?g. }

• W2883103417 abstract "Abstract In eukaryotic translation the 60S ribosome subunit has not been proposed to interact with mRNA or closed-loop factors eIF4E, eIF4G, and PAB1. Using analytical ultracentrifugation with fluorescent detection system, we have identified a 57S translation complex that contains the 60S ribosome, mRNA, and the closed-loop factors. Previously published data by others also indicate the presence of a 50S-60S translation complex containing these same components. We have found that the abundance of this complex increased upon translational cessation, implying formation after ribosomal dissociation. Stoichiometric analyses of the abundances of the closed-loop components in the 57S complex indicate this complex is most similar to polysomal and monosomal translation complexes at the end of translation rather than at the beginning or middle of translation. In contrast, a 39S complex containing the 40S ribosome bound to mRNA and closed-loop factors was also identified with stoichiometries most similar to polysomal complexes engaged in translation, suggesting that the 39S complex is the previously studied 48S translation initiation complex. These results indicate that the 60S ribosome can associate with the closed-loop mRNA structure and plays a previously undetected role in the translation process." @default.
• W2883103417 created "2018-08-03" @default.
• W2883103417 creator A5006822602 @default.
• W2883103417 creator A5048915972 @default.
• W2883103417 creator A5052956560 @default.
• W2883103417 date "2018-07-31" @default.
• W2883103417 modified "2023-10-12" @default.
• W2883103417 title "Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit" @default.
• W2883103417 cites W1565619177 @default.
• W2883103417 cites W1758820812 @default.
• W2883103417 cites W1924846174 @default.
• W2883103417 cites W1967771842 @default.
• W2883103417 cites W1969264016 @default.
• W2883103417 cites W1976367392 @default.
• W2883103417 cites W1976837580 @default.
• W2883103417 cites W1981247632 @default.
• W2883103417 cites W1983432834 @default.
• W2883103417 cites W1990937411 @default.
• W2883103417 cites W1994952886 @default.
• W2883103417 cites W2000789682 @default.
• W2883103417 cites W2003084616 @default.
• W2883103417 cites W2012538868 @default.
• W2883103417 cites W2013126209 @default.
• W2883103417 cites W2034774838 @default.
• W2883103417 cites W2037313242 @default.
• W2883103417 cites W2047430852 @default.
• W2883103417 cites W2049477020 @default.
• W2883103417 cites W2070085869 @default.
• W2883103417 cites W2071060257 @default.
• W2883103417 cites W2077829198 @default.
• W2883103417 cites W2090833743 @default.
• W2883103417 cites W2095848833 @default.
• W2883103417 cites W2104825395 @default.
• W2883103417 cites W2108655462 @default.
• W2883103417 cites W2108931507 @default.
• W2883103417 cites W2109535551 @default.
• W2883103417 cites W2117291177 @default.
• W2883103417 cites W2119846936 @default.
• W2883103417 cites W2123716335 @default.
• W2883103417 cites W2123742352 @default.
• W2883103417 cites W2123827414 @default.
• W2883103417 cites W2128634298 @default.
• W2883103417 cites W2129448413 @default.
• W2883103417 cites W2130256267 @default.
• W2883103417 cites W2131514494 @default.
• W2883103417 cites W2136433399 @default.
• W2883103417 cites W2137649514 @default.
• W2883103417 cites W2139987194 @default.
• W2883103417 cites W2141325721 @default.
• W2883103417 cites W2160516095 @default.
• W2883103417 cites W2166745847 @default.
• W2883103417 cites W2167065999 @default.
• W2883103417 cites W2168383988 @default.
• W2883103417 cites W2169805130 @default.
• W2883103417 cites W2261626656 @default.
• W2883103417 cites W2300213271 @default.
• W2883103417 cites W2414382575 @default.
• W2883103417 cites W2530329951 @default.
• W2883103417 cites W2740852495 @default.
• W2883103417 cites W2768613443 @default.
• W2883103417 cites W65711592 @default.
• W2883103417 doi "https://doi.org/10.1038/s41598-018-29832-6" @default.
• W2883103417 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6068138" @default.
• W2883103417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30065356" @default.
• W2883103417 hasPublicationYear "2018" @default.
• W2883103417 type Work @default.
• W2883103417 sameAs 2883103417 @default.
• W2883103417 citedByCount "2" @default.
• W2883103417 countsByYear W28831034172020 @default.
• W2883103417 countsByYear W28831034172021 @default.
• W2883103417 crossrefType "journal-article" @default.
• W2883103417 hasAuthorship W2883103417A5006822602 @default.
• W2883103417 hasAuthorship W2883103417A5048915972 @default.
• W2883103417 hasAuthorship W2883103417A5052956560 @default.
• W2883103417 hasBestOaLocation W28831034171 @default.
• W2883103417 hasConcept C104317684 @default.
• W2883103417 hasConcept C105580179 @default.
• W2883103417 hasConcept C129194359 @default.
• W2883103417 hasConcept C149364088 @default.
• W2883103417 hasConcept C161295673 @default.
• W2883103417 hasConcept C182325514 @default.
• W2883103417 hasConcept C185592680 @default.
• W2883103417 hasConcept C2776054693 @default.
• W2883103417 hasConcept C301363 @default.
• W2883103417 hasConcept C4718897 @default.
• W2883103417 hasConcept C54355233 @default.
• W2883103417 hasConcept C62493599 @default.
• W2883103417 hasConcept C67705224 @default.
• W2883103417 hasConcept C77430603 @default.
• W2883103417 hasConcept C86803240 @default.
• W2883103417 hasConcept C88478588 @default.
• W2883103417 hasConcept C95444343 @default.
• W2883103417 hasConceptScore W2883103417C104317684 @default.
• W2883103417 hasConceptScore W2883103417C105580179 @default.
• W2883103417 hasConceptScore W2883103417C129194359 @default.
• W2883103417 hasConceptScore W2883103417C149364088 @default.
• W2883103417 hasConceptScore W2883103417C161295673 @default.
• W2883103417 hasConceptScore W2883103417C182325514 @default.
• W2883103417 hasConceptScore W2883103417C185592680 @default.
• W2883103417 hasConceptScore W2883103417C2776054693 @default.

• next