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- W2883152869 abstract "Using Indium-oxine as platelet label, we performed platelet kinetic studies in 30 patients with ascitic cirrhosis. Spleen size was also assessed. All results were compared to that found in 10 controls Seven patients had platelet kinetics not different from controls. Five of them were thrombopenie, and presented probably a platelet production insufficiency. Eighteen patients had a shortened platelet survival (less than 7.5 days). These patients were thrombocytopenic and presented a platelet destruction. The major site of destruction was splenic in ten out of these 18 patients. Only five patients had a normal platelet lifespan and an increased splenic pooling. No correlation was found between the following parameters: platelet count, platelet survival, splenic uptake of the radioactivity, spleen size. It is concluded that in patients with liver cirrhosis and portal hypertension: 1) Hypersplenism (normal platelet survival and high splenic pooling) is a rare cause of thrombopenia. 2) Thrombopenia is probably due to several mechanisms which are associated in a same patient and which are independent of the spleen size." @default.
- W2883152869 created "2018-08-03" @default.
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- W2883152869 date "1981-01-01" @default.
- W2883152869 modified "2023-10-17" @default.
- W2883152869 title "Indium Labeled Platelet Kinetics In Ascitic Cirrhosis" @default.
- W2883152869 doi "https://doi.org/10.1055/s-0038-1653282" @default.
- W2883152869 hasPublicationYear "1981" @default.
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