Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883153351> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2883153351 endingPage "25" @default.
- W2883153351 startingPage "21" @default.
- W2883153351 abstract "Background: HbA1c is a well-known and widely accepted marker for monitoring glycaemic control in patients with Diabetes Mellitus. It has also been shown to predict long term microvascular complications associated with Diabetes Mellitus. As a result the International Expert Committee has endorsed HbA1c as a diagnostic marker for Diabetes Mellitus. There are several assays available for the measurement of HbA1c and the recommended assay performance is an intralaboratory coefficient of variation of <2%. The aim of the study was to evaluate the analytical performance of the HbA1c enzymatic assay on the Abbott Architect ci8200. Method: The precision, reportable range and bias were determined by following The Clinical and Laboratory Standards Institute (CLSI) EP05, EP06 and EP15 guidelines. Bias was determined by comparison between the Abbott Architect and the Biorad Variant II analyser. Results: The total impresicion for low and high controls was 1.06% and 1.8% respectively. The assay demonstrated excellent correlation with the Biorad Variant II analyser with a slope of 0.923, intercept of 0.569 and R2 of 0.978. The Bland-Altman mean difference was 0.044 between the Abbott Architect and Biorad Variant II analysers. At the diagnostic and monitoring cut-off, the bias was found to be 1.05% and 0.43% respectively. Conclusion: The new enzymatic HbA1c assay demonstrated good precision and had the advantage of rapid analysis thus prompt results reporting. The study also demonstrated acceptable agreement of the Abbott Architect and Bio-Rad Variant II methods across the measured range. Notably, the assay met analytical goals for the diagnosis and monitoring of Diabetes Mellitus using, as the total allowable error was 1.13% and 1.03% respectively, which was well below the 3% total allowable recommended error from biological data." @default.
- W2883153351 created "2018-08-03" @default.
- W2883153351 creator A5086084664 @default.
- W2883153351 date "2018-07-25" @default.
- W2883153351 modified "2023-09-23" @default.
- W2883153351 title "HbA1c enzymatic assay evaluation at an academic laboratory" @default.
- W2883153351 doi "https://doi.org/10.4102/mtsa.v32i1.167" @default.
- W2883153351 hasPublicationYear "2018" @default.
- W2883153351 type Work @default.
- W2883153351 sameAs 2883153351 @default.
- W2883153351 citedByCount "0" @default.
- W2883153351 crossrefType "journal-article" @default.
- W2883153351 hasAuthorship W2883153351A5086084664 @default.
- W2883153351 hasConcept C126322002 @default.
- W2883153351 hasConcept C134018914 @default.
- W2883153351 hasConcept C185592680 @default.
- W2883153351 hasConcept C26834552 @default.
- W2883153351 hasConcept C3020132585 @default.
- W2883153351 hasConcept C43617362 @default.
- W2883153351 hasConcept C555293320 @default.
- W2883153351 hasConcept C71924100 @default.
- W2883153351 hasConcept C89838059 @default.
- W2883153351 hasConceptScore W2883153351C126322002 @default.
- W2883153351 hasConceptScore W2883153351C134018914 @default.
- W2883153351 hasConceptScore W2883153351C185592680 @default.
- W2883153351 hasConceptScore W2883153351C26834552 @default.
- W2883153351 hasConceptScore W2883153351C3020132585 @default.
- W2883153351 hasConceptScore W2883153351C43617362 @default.
- W2883153351 hasConceptScore W2883153351C555293320 @default.
- W2883153351 hasConceptScore W2883153351C71924100 @default.
- W2883153351 hasConceptScore W2883153351C89838059 @default.
- W2883153351 hasIssue "1" @default.
- W2883153351 hasLocation W28831533511 @default.
- W2883153351 hasOpenAccess W2883153351 @default.
- W2883153351 hasPrimaryLocation W28831533511 @default.
- W2883153351 hasRelatedWork W161350945 @default.
- W2883153351 hasRelatedWork W1860937238 @default.
- W2883153351 hasRelatedWork W1957866003 @default.
- W2883153351 hasRelatedWork W1985278698 @default.
- W2883153351 hasRelatedWork W2008033326 @default.
- W2883153351 hasRelatedWork W2015340325 @default.
- W2883153351 hasRelatedWork W2056833834 @default.
- W2883153351 hasRelatedWork W2058874332 @default.
- W2883153351 hasRelatedWork W2126028333 @default.
- W2883153351 hasRelatedWork W2314919559 @default.
- W2883153351 hasRelatedWork W2335088804 @default.
- W2883153351 hasRelatedWork W2424559897 @default.
- W2883153351 hasRelatedWork W2590221124 @default.
- W2883153351 hasRelatedWork W2617530908 @default.
- W2883153351 hasRelatedWork W2734572501 @default.
- W2883153351 hasRelatedWork W2891281853 @default.
- W2883153351 hasRelatedWork W2897748245 @default.
- W2883153351 hasRelatedWork W2948995452 @default.
- W2883153351 hasRelatedWork W2973130100 @default.
- W2883153351 hasRelatedWork W3048219163 @default.
- W2883153351 hasVolume "32" @default.
- W2883153351 isParatext "false" @default.
- W2883153351 isRetracted "false" @default.
- W2883153351 magId "2883153351" @default.
- W2883153351 workType "article" @default.