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• W2883179900 abstract "In this study, 19 octadecanoid derivatives-four pairs of enantiomers (1⁻8), two racemic/scalemic mixtures (9⁻10), and nine biosynthetically related analogues-were obtained from the ethanolic extract of a Chinese medicinal plant, Plantago depressa Willd. Their structures were elucidated on the basis of detailed spectroscopic analyses, with the absolute configurations of the new compounds assigned by time-dependent density functional theory (TD-DFT)-based electronic circular dichroism (ECD) calculations. Six of them (1, 3⁻6, and 9) were reported for the first time, while 2, 7, and 8 have been previously described as derivatives and are currently obtained as natural products. Our bioassays have established that selective compounds show in vitro anti-inflammatory activity by inhibiting lipopolysaccharide-induced nitric oxide (NO) production in mouse macrophage RAW 264.7 cells." @default.
• W2883179900 created "2018-08-03" @default.
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• W2883179900 date "2018-07-14" @default.
• W2883179900 modified "2023-10-14" @default.
• W2883179900 title "New Octadecanoid Enantiomers from the Whole Plants of Plantago depressa" @default.
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• W2883179900 doi "https://doi.org/10.3390/molecules23071723" @default.
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