Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883250470> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2883250470 endingPage "270" @default.
- W2883250470 startingPage "239" @default.
- W2883250470 abstract "Delivery of a cancer therapeutic to its intended extracellular or intracellular target, which is required for achieving therapeutic efficacy, involves multiple kinetic processes. This chapter outlines the complex and dynamic biological properties of solid tumors that may limit the therapeutic from reaching its target, and describes the application of chemical engineering tools (e.g., multiscale modeling and computational fluid dynamics) in quantitative systems pharmacology research. The discussions include both conventional small-molecule drugs and nanotherapeutics as the latter represents a new promising therapeutic strategy in translational cancer research. Examples of our earlier work demonstrate the successful use of computational modeling to predict drug delivery in solid tumors as functions of time and intratumoral location and to use such predictions for therapy development in cancer patients." @default.
- W2883250470 created "2018-08-03" @default.
- W2883250470 creator A5014759207 @default.
- W2883250470 creator A5085031128 @default.
- W2883250470 date "2018-01-01" @default.
- W2883250470 modified "2023-10-17" @default.
- W2883250470 title "Quantitative systems pharmacology on cancer drug delivery to target sites: Application of chemical engineering tools" @default.
- W2883250470 cites W1593844282 @default.
- W2883250470 cites W1964532468 @default.
- W2883250470 cites W1967389270 @default.
- W2883250470 cites W1967513395 @default.
- W2883250470 cites W1996376324 @default.
- W2883250470 cites W2014259987 @default.
- W2883250470 cites W2014630203 @default.
- W2883250470 cites W2024392622 @default.
- W2883250470 cites W2041733648 @default.
- W2883250470 cites W2041826024 @default.
- W2883250470 cites W2042365192 @default.
- W2883250470 cites W2044526272 @default.
- W2883250470 cites W2047209914 @default.
- W2883250470 cites W2052067026 @default.
- W2883250470 cites W2068942685 @default.
- W2883250470 cites W2071176926 @default.
- W2883250470 cites W2081054963 @default.
- W2883250470 cites W2083093086 @default.
- W2883250470 cites W2086796015 @default.
- W2883250470 cites W2095199024 @default.
- W2883250470 cites W2098447374 @default.
- W2883250470 cites W2098934895 @default.
- W2883250470 cites W2135026122 @default.
- W2883250470 cites W2136778199 @default.
- W2883250470 cites W2193100265 @default.
- W2883250470 cites W2413795989 @default.
- W2883250470 cites W2418110730 @default.
- W2883250470 cites W2425352883 @default.
- W2883250470 cites W2613872696 @default.
- W2883250470 cites W3022047930 @default.
- W2883250470 cites W656093389 @default.
- W2883250470 cites W69052102 @default.
- W2883250470 doi "https://doi.org/10.1016/b978-0-444-63964-6.00008-8" @default.
- W2883250470 hasPublicationYear "2018" @default.
- W2883250470 type Work @default.
- W2883250470 sameAs 2883250470 @default.
- W2883250470 citedByCount "3" @default.
- W2883250470 countsByYear W28832504702019 @default.
- W2883250470 countsByYear W28832504702023 @default.
- W2883250470 crossrefType "book-chapter" @default.
- W2883250470 hasAuthorship W2883250470A5014759207 @default.
- W2883250470 hasAuthorship W2883250470A5085031128 @default.
- W2883250470 hasConcept C121608353 @default.
- W2883250470 hasConcept C126322002 @default.
- W2883250470 hasConcept C171250308 @default.
- W2883250470 hasConcept C192562407 @default.
- W2883250470 hasConcept C2779820397 @default.
- W2883250470 hasConcept C2780035454 @default.
- W2883250470 hasConcept C2983331546 @default.
- W2883250470 hasConcept C41008148 @default.
- W2883250470 hasConcept C70721500 @default.
- W2883250470 hasConcept C71924100 @default.
- W2883250470 hasConcept C86803240 @default.
- W2883250470 hasConcept C98274493 @default.
- W2883250470 hasConceptScore W2883250470C121608353 @default.
- W2883250470 hasConceptScore W2883250470C126322002 @default.
- W2883250470 hasConceptScore W2883250470C171250308 @default.
- W2883250470 hasConceptScore W2883250470C192562407 @default.
- W2883250470 hasConceptScore W2883250470C2779820397 @default.
- W2883250470 hasConceptScore W2883250470C2780035454 @default.
- W2883250470 hasConceptScore W2883250470C2983331546 @default.
- W2883250470 hasConceptScore W2883250470C41008148 @default.
- W2883250470 hasConceptScore W2883250470C70721500 @default.
- W2883250470 hasConceptScore W2883250470C71924100 @default.
- W2883250470 hasConceptScore W2883250470C86803240 @default.
- W2883250470 hasConceptScore W2883250470C98274493 @default.
- W2883250470 hasLocation W28832504701 @default.
- W2883250470 hasOpenAccess W2883250470 @default.
- W2883250470 hasPrimaryLocation W28832504701 @default.
- W2883250470 hasRelatedWork W2002675502 @default.
- W2883250470 hasRelatedWork W2061955697 @default.
- W2883250470 hasRelatedWork W2130337453 @default.
- W2883250470 hasRelatedWork W2337597952 @default.
- W2883250470 hasRelatedWork W2408703666 @default.
- W2883250470 hasRelatedWork W2538854790 @default.
- W2883250470 hasRelatedWork W2604084092 @default.
- W2883250470 hasRelatedWork W3023582450 @default.
- W2883250470 hasRelatedWork W3209045103 @default.
- W2883250470 hasRelatedWork W4205976727 @default.
- W2883250470 isParatext "false" @default.
- W2883250470 isRetracted "false" @default.
- W2883250470 magId "2883250470" @default.
- W2883250470 workType "book-chapter" @default.