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- W2883352070 endingPage "1065" @default.
- W2883352070 startingPage "1051" @default.
- W2883352070 abstract "The introduction of prion RT-QuIC, an ultrasensitive specific assay for the in vivo detection of the abnormal prion protein, has significantly increased the potential for an early and accurate clinical diagnosis of Creutzfeldt-Jakob disease (CJD). However, in the clinical setting, the early identif ication of patients with possible CJD is often challenging. Indeed, CJD patients may present with isolated symptoms that remain the only clinical manifestation for some time, or with neurological syndromes atypical for CJD. To enhance awareness of unusual disease presentations and promote earlier diagnosis, we reviewed the entire spectrum of atypical early manifestations of CJD, mainly reported to date as case descriptions or small case series. They included sensory either visual or auditory disturbances, seizures, isolated psychiatric manifestations, atypical parkinsonian syndromes (corticobasal syndrome, progressive supranuclear palsy-like), pseudobulbar syndrome, isolated involuntary movements (dystonia, myoclonus, chorea, blepharospasm), acute or subacute onsets mimicking a stroke, isolated aphasia, and neuropathy. Since CJD is a rare disease and its clinical course rapidly progressive, an in-depth understanding and awareness of early clinical features are mandatory to enhance the overall diagnostic accuracy in its very early stages and to recruit optimal candidates for future therapeutic trials." @default.
- W2883352070 created "2018-08-03" @default.
- W2883352070 creator A5011558537 @default.
- W2883352070 creator A5023875722 @default.
- W2883352070 creator A5034396279 @default.
- W2883352070 creator A5077646545 @default.
- W2883352070 date "2018-07-24" @default.
- W2883352070 modified "2023-10-18" @default.
- W2883352070 title "Unusual Clinical Presentations Challenging the Early Clinical Diagnosis of Creutzfeldt-Jakob Disease" @default.
- W2883352070 cites W1551019054 @default.
- W2883352070 cites W1633252395 @default.
- W2883352070 cites W190478361 @default.
- W2883352070 cites W1964552624 @default.
- W2883352070 cites W1970272436 @default.
- W2883352070 cites W1970429780 @default.
- W2883352070 cites W1971168935 @default.
- W2883352070 cites W1973709650 @default.
- W2883352070 cites W1974232858 @default.
- W2883352070 cites W1975609898 @default.
- W2883352070 cites W1976112863 @default.
- W2883352070 cites W1977006687 @default.
- W2883352070 cites W1981393303 @default.
- W2883352070 cites W1984273933 @default.
- W2883352070 cites W1984717011 @default.
- W2883352070 cites W1986388560 @default.
- W2883352070 cites W1986748953 @default.
- W2883352070 cites W1995818736 @default.
- W2883352070 cites W1998119561 @default.
- W2883352070 cites W1998135451 @default.
- W2883352070 cites W1998397843 @default.
- W2883352070 cites W1999610380 @default.
- W2883352070 cites W1999844663 @default.
- W2883352070 cites W2000426464 @default.
- W2883352070 cites W2014313206 @default.
- W2883352070 cites W2018438509 @default.
- W2883352070 cites W2020295090 @default.
- W2883352070 cites W2024353597 @default.
- W2883352070 cites W2026619686 @default.
- W2883352070 cites W2027679931 @default.
- W2883352070 cites W2028774611 @default.
- W2883352070 cites W2028846899 @default.
- W2883352070 cites W2031063093 @default.
- W2883352070 cites W2032411456 @default.
- W2883352070 cites W2033196701 @default.
- W2883352070 cites W2034630834 @default.
- W2883352070 cites W2034771142 @default.
- W2883352070 cites W2041811192 @default.
- W2883352070 cites W2046440748 @default.
- W2883352070 cites W2048354803 @default.
- W2883352070 cites W2048804934 @default.
- W2883352070 cites W2050107479 @default.
- W2883352070 cites W2052243360 @default.
- W2883352070 cites W2052931950 @default.
- W2883352070 cites W2053039379 @default.
- W2883352070 cites W2053606444 @default.
- W2883352070 cites W2053645625 @default.
- W2883352070 cites W2053849276 @default.
- W2883352070 cites W2054031692 @default.
- W2883352070 cites W2056151116 @default.
- W2883352070 cites W2056959753 @default.
- W2883352070 cites W2058042264 @default.
- W2883352070 cites W2060849620 @default.
- W2883352070 cites W2063970029 @default.
- W2883352070 cites W2066051725 @default.
- W2883352070 cites W2067500690 @default.
- W2883352070 cites W2071218976 @default.
- W2883352070 cites W2074173136 @default.
- W2883352070 cites W2075965750 @default.
- W2883352070 cites W2076056216 @default.
- W2883352070 cites W2077081993 @default.
- W2883352070 cites W2078549130 @default.
- W2883352070 cites W2079038281 @default.
- W2883352070 cites W2079283960 @default.
- W2883352070 cites W2079304641 @default.
- W2883352070 cites W2079369497 @default.
- W2883352070 cites W2081741270 @default.
- W2883352070 cites W2082659503 @default.
- W2883352070 cites W2083851817 @default.
- W2883352070 cites W2084141041 @default.
- W2883352070 cites W2084346405 @default.
- W2883352070 cites W2086588262 @default.
- W2883352070 cites W2088175299 @default.
- W2883352070 cites W2090843282 @default.
- W2883352070 cites W2092556927 @default.
- W2883352070 cites W2092622586 @default.
- W2883352070 cites W2093581573 @default.
- W2883352070 cites W2096206310 @default.
- W2883352070 cites W2098479349 @default.
- W2883352070 cites W2099553290 @default.
- W2883352070 cites W2108360977 @default.
- W2883352070 cites W2116240168 @default.
- W2883352070 cites W2116429998 @default.
- W2883352070 cites W2117848707 @default.
- W2883352070 cites W2122784925 @default.
- W2883352070 cites W2122820088 @default.
- W2883352070 cites W2132033857 @default.
- W2883352070 cites W2133112490 @default.
- W2883352070 cites W2138007061 @default.